Blood Res.  2020 Jun;55(2):120-123. 10.5045/br.2020.2020052.

Large granular lymphocytes (LGL) in primary Sjögren syndrome (pSS): immunophenotype and review on the pathological role of T cells in pSS

Affiliations
  • 1Department of Clinical and Experimental Medicine, Section of Haematology, University of Pisa, Pisa, Italy


Figure

  • Fig. 1 (A) Immunophenotyping of circulating lymphocytes at the last observation (above) compared with immunophenotyping of circulating lymphocytes in a healthy donor (below). (B) TCR β and δ receptor rearrangements. TCR β (above) shows a monoclonal rearrangement, while TCR δ (below) is polyclonal.Abbreviations: CM, central memory T CD8+ cells; EM, effector memory T CD8+ cells; naïve, naïve T CD8+ cells; TEMRA, terminal effector memory T CD8+ cells.

  • Fig. 2 Graph detailing variations in lymphocyte numbers during observation.


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