J Korean Diabetes.  2018 Dec;19(4):208-213. 10.4093/jkd.2018.19.4.208.

Effective Management of Diabetic Ketoacidosis

Affiliations
  • 1Division of Endocrinology and Metabolism, Department of Internal Medicine, Chonnam National University Hospital, Chonnam National University Medical School, Gwangju, Korea. choshua@chol.com

Abstract

Diabetic ketoacidosis (DKA) is serious complication of diabetes mellitus that requires prompt recognition, diagnosis and treatment. It is characterized by a triad of uncontrolled hyperglycemia, metabolic acidosis, and increased total body ketone concentration. The overall DKA mortality rate recorded among children and adults is < 1%. For patients with DKA, appropriate administration of intravenous fluids and insulin with attention to associated fluid and electrolyte disorders can effectively and rapidly resolve metabolic dysregulation. Following acute management and restoration of physiological glucose levels, DKA requires identification of the precipitating cause to prevent recurrence of potentially life-threatening diabetic complications.

Keyword

Diabetes mellitus; Diabetic ketoacidosis; Hyperglycemia; Ketonemia

MeSH Terms

Acidosis
Adult
Child
Diabetes Complications
Diabetes Mellitus
Diabetic Ketoacidosis*
Diagnosis
Glucose
Humans
Hyperglycemia
Insulin
Ketosis
Mortality
Recurrence
Glucose
Insulin

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