J Rhinol.
2001 May;8(1, 2):58-62.
The Effect of Capsaicin Spray in Nasal Hyperreactivity
- Affiliations
-
- 1Department of Otorhinolaryngology, College of Medicine, InHa University, Incheon, Korea. JangTY@inha.ac.kr
- 2Department of Otolaryngology, Incheon Christian Hospital, Incheon, Korea.
Abstract
- Capsaicin, a nonenamide derived from Capsicum plants, has proven to be useful in patients with vasomotor rhintitis. In this study, we estimated the effects of 10-5 M capsaicin spray in patients with hypersensitive rhinitis. The drug was given 3 times per day for 3 days to each patient by means of a spray delivered to the nasal mucosa. Patient's symptom score was recorded by the same physician. We repeated this method after 1 week, 2 week, 4week, 8week, 12week, 16week and recorded their symptom score. As a result, the mean symptom score involving nasal obstruction, sneezing, rhinorrhea and itching was remarkably reduced by capsaicin spray. The present findings suggest that capsacine spray is a good therpheutic method for hypersensitive rhinitis patients.
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