Korean J Psychopharmacol.
2014 Oct;25(4):155-160. 10.0000/kjp.2014.25.4.155.
Korean Medication Algorithm for Bipolar Disorder 2014: Medical Comorbidity
- Affiliations
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- 1Department of Psychiatry, Jeju National University Hospital, Jeju, Korea.
- 2Department of Psychiatry, Haeundae Paik Hospital and Paik Institute for Clinical Research, College of Medicine, Inje University, Department of Health Science and Technology, Graduate of School of Inje University, Busan, Korea.
- 3Department of Psychiatry, Naju National Hospital, Naju, Korea.
- 4Department of Psychiatry, St. Vincent's Hospital, College of Medicine, The Catholic University of Korea, Suwon, Korea.
- 5Department of Psychiatry, Keyo Hospital, Keyo Medical Foundation, Uiwang, Korea.
- 6Department of Psychiatry, Soonchunhyang University Cheonan Hospital, College of Medicine, Soonchunhyang University, Cheonan, Korea.
- 7Department of Psychiatry, Yeouido St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Korea. wmbahk@catholic.ac.kr
- 8Department of Psychiatry, Hallym University Sacred Heart Hospital, College of Medicine, Hallym University, Anyang, Korea.
- 9Department of Psychiatry, Konkuk University Chungju Hospital, School of Medicine, Konkuk University, Chungju, Korea.
- 10Department of Psychiatry, Kangbuk Samsung Hospital, School of Medicine, Sungkyunkwan University, Seoul, Korea.
- 11Department of Psychiatry, College of Medicine, Chung-Ang University, Seoul, Korea. kjoonmin@gmail.com
- KMID: 2287762
- DOI: http://doi.org/10.0000/kjp.2014.25.4.155
Abstract
OBJECTIVE
The third revision of Korean Medication Algorithm Project for Bipolar Disorder was performed in 2014 in order to provide more proper guideline for clinicians. In this study, we undertook a survey of expert opinion to help clinical decisions in medical comorbidities.
METHODS
The questionnaire to survey the expert opinion of medication for bipolar disorder was completed by the review committee consisting of 64 experienced psychiatrists. This survey was composed of 56 main questionnaires of which the contents covered from overall treatment strategies to treatment strategies under the specific situations. The executive committee analyzed the results and discussed the final production of algorithm.
RESULTS
In bipolar patients with cardiovascular, diabetic, or hepatic comorbidities, aripiprazole was first-line treatment strategy. In case of renal comorbidity accompanying bipolar disorder, aripiprazole, valproate, and quetiapine were preferred. Valproate was recommended as the first-line strategy in case of bipolar disorder with cerebrovascular diseases.
CONCLUSION
This study provided information about the consensus among experts in regard to treatment strategies for bipolar disorder in the medically ill.
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