Korean J Dermatol.  2012 May;50(5):468-471.

Primary Cutaneous Nocardiosis with Sporotrichoid Pattern by N. brasiliensis in Lung Cancer Patient

Affiliations
  • 1Department of Dermatology, School of Medicine, Keimyung University, Daegu, Korea. janylove99@dsmc.or.kr
  • 2Department of Laboratory Medicine, School of Medicine, Keimyung University, Daegu, Korea.

Abstract

Nocardia is aerobic gram positive bacteria, which is found in the soil. Cutaneous nocardiosis is divided into the primary skin infection and secondary infection due to systemic dissemination from the internal organ. Its clinical manifestations are mycetoma, lymphocutaneous infection and superficial infection, such as abscess or granuloma. In lymphocutaneous infection, it is important to make differential diagnosis with other diseases with sporotrichoid pattern, such as sporotrichosis, leishmaniasis and mycobacterial infection. In our case, 58 year old male who had history of chemotherapy due to lung cancer visited with granulomatous nodule on the left wrist, and following lymphangitis along the forearm for 2 months. Through a skin biopsy, culture, AFB stain and 16S rRNA gene sequencing, cutaneous nocardiosis by N. brasiliensis was diagnosed.

Keyword

Cancer; Nocardia; Sporotrichoid

MeSH Terms

Abscess
Biopsy
Coinfection
Diagnosis, Differential
Forearm
Genes, rRNA
Gram-Positive Bacteria
Granuloma
Humans
Leishmaniasis
Lung
Lung Neoplasms
Lymphangitis
Male
Mycetoma
Nocardia
Nocardia Infections
Skin
Soil
Sporotrichosis
Wrist
Nocardia Infections
Soil
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