Korean J Gastroenterol.  2000 Mar;35(3):309-318.

Role of Dynamic Magnetic Resonance Imaging in the T-Staging of Advanced Stomach Cancer

• Kang BC
• Baek SY
• Lee SW

Abstract

We evaluated the usefulness of the dynamic and delayed magnetic resonance (MR) imaging in the T staging of advanced stomach cancer.
METHODS
Authors performed the MR imaging in 42 patients with advanced gastric cancer. Two dimension-fast low-angle shot (2D-FLASH) MR images for the water-distended stomach were obtained with dynamic protocol after intravenous injection of the 0.1 mM Gd-DTPA (gadopentetate dimeglumine) /kg solution. We prospectively evaluated the depth of cancer invasion, perigastric infiltration(extraserosal invasion), perigastric organ invasion. We correlated the MR-determined T-staging with the surgicopathologic findings.
RESULTS
The mucosa (or with submucosa) invaded by stomach cancer showed early enhancement patterrn in 39 patients (93%) 30 to 90 seconds after Gd-DTPA administration. The normal gastric mucosa demonstrated delayed peak enhancement pattern in 24 patients (57%) or variable enhancement pattern in 18 patients (43%). Interrupted low signal intensity band or highly-enhanced tumorous lesion penetrating through gastric wall were observed in 17 of 19 pT3 patients (90%). Consistency between MR-determined stage and surgicopathologic staging was observed in 10 of 13 pT2 tumors (77%), 17 of 19 pT3 tumors (90%), and 8 of 10 pT4 tumors (80%). The overall accuracy was 83%.
CONCLUSIONS
Dynamic MR imaging can be useful for T-staging of advanced gastric cancer.

Keyword

Stomach; Magnetic Resonance Imaging; Neoplasm; Staging

MeSH Terms

Gadolinium DTPA
Gastric Mucosa
Humans
Injections, Intravenous
Magnetic Resonance Imaging*
Mucous Membrane
Prospective Studies
Stomach Neoplasms*
Stomach*
Gadolinium DTPA