J Rheum Dis.  2014 Feb;21(1):43-45. 10.4078/jrd.2014.21.1.43.

A Case of Descending Thoracic and Abdominal Aortic Aneurysm with Ankylosing Spondylitis

Affiliations
  • 1Division of Rheumatology, Department of Internal Medicine, Seoul St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Korea. rapark@catholic.ac.kr

Abstract

Ankylosing spondylitis (AS) is a systemic inflammatory disorder that affects the axial skeleton. It often involves the extra-articular organs. Cardiovascular involvement is one of the extra-articular manifestations, which is mostly represented by aortic root, valvular heart disease, and conduction disturbances. An aortic sclerosing inflammatory process induces aortic root thickening and rigidity. An aortic aneurysmal change is a rare complication that often leads to life threatening conditions. A few cases regarding aortic aneurysm have been reported, but there are no reported cases in Korea. We report the first case of descending thoracic and abdominal aortic aneurysm in a patient with ankylosing spondylitis.

Keyword

Ankylosing spondylitis; Extra-articular manifestation; Cardiovascular; Aortic aneurysm

MeSH Terms

Aortic Aneurysm
Aortic Aneurysm, Abdominal*
Heart Valve Diseases
Humans
Korea
Skeleton
Spondylitis, Ankylosing*

Figure

  • Figure 1. Sacroiliitis at initial presentation. (A) Subchondral sclerosis with periarticular erosions were observed at both sacroiliac joint in plain pelvic X-ray. Narrowing of the sacroiliac spaces also could be seen (arrowheads: Sacroiliitis, New York classification III). (B) Pelvic magnetic resonance imaging showed bone marrow edema and joint space narrowing in right sacroiliac joint. Also synovial enhancement and subchondral erosions were seen (arrow).

  • Figure 2. Incidentally detected aortic aneurysm. (A) Chest computed tomographic imaging of three-dimensional reconstruction shows a dilated descending aorta (yellow arrows). Aortic root and aortic arch appeared to be normal. (B) Continuing abdominal aortic aneurysm involves the suprarenal and infrarenal segment of abdominal aorta (white arrows).


Reference

References

1. Vander Cruyssen B, Ribbens C, Boonen A, Mielants H, de Vlam K, Lenaerts J, et al. The epidemiology of ankylosing spondylitis and the commencement of anti-TNF therapy in daily rheumatology practice. Ann Rheum Dis. 2007; 66:1072–7.
2. Lautermann D, Braun J. Ankylosing spondylitis–cardiac manifestations. Clin Exp Rheumatol. 2002; 20(6 Suppl 28):S11–5.
3. Roldan CA. Valvular and coronary heart disease in systemic inflammatory diseases: Systemic Disorders in heart disease. Heart. 2008; 94:1089–101.
4. Roldan CA, Chavez J, Wiest PW, Qualls CR, Crawford MH. Aortic root disease and valve disease associated with ankylosing spondylitis. J Am Coll Cardiol. 1998; 32:1397–404.
Article
5. Graham DC, Smythe HA. The carditis and aortitis of ankylosing spondylitis. Bull Rheum Dis. 1958; 9:171–4.
6. Kim TJ, Kim TH. Clinical spectrum of ankylosing spondylitis in Korea. Joint Bone Spine. 2010; 77:235–40.
Article
7. Palazzi C, D' Angelo S, Lubrano E, Olivieri I. Aortic involvement in ankylosing spondylitis. Clin Exp Rheumatol. 2008; 26(3 Suppl 49):S131–4.
8. Bulkley BH, Roberts WC. Ankylosing spondylitis and aortic regurgitation. Description of the characteristic cardiovascular lesion from study of eight necropsy patients. Circulation. 1973; 48:1014–27.
9. El Maghraoui A. Extra-articular manifestations of ankylosing spondylitis: prevalence, characteristics and therapeutic implications. Eur J Intern Med. 2011; 22:554–60.
Article
10. Yuan SM. Cardiovascular involvement of ankylosing spondylitis: report of three cases. Vascular. 2009; 17:342–54.
Article
11. Bakland G, Gran JT, Nossent JC. Increased mortality in ankylosing spondylitis is related to disease activity. Ann Rheum Dis. 2011; 70:1921–5.
Article
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