J Rheum Dis.  2016 Apr;23(2):118-121. 10.4078/jrd.2016.23.2.118.

A Case of Azygos Vein Thombosis Associated with Transient Antiphospholipid Syndrome in Urinary Tract Infection with Escherichia coli

Affiliations
  • 1Division of Nephrology, Department of Internal Medicine, Seoul Red Cross Hospital, Seoul, Korea. moeru1@naver.com
  • 2Department of Nephrology, Kyung Hee University School of Medicine, Seoul, Korea.

Abstract

A 73-year-old female with diabetes admitted for treatment of an intertrochanter fracture of the femur and a urinary tract infection (UTI) with Escherichia coli developed thrombosis in her right azygos vein, which was thought to be associated with antiphospholipid and immunoglobulin M anticardiolipin antibodies. After antibiotic therapy, antiphospholipid antibody was undetectable, and a repeat chest computed tomography showed complete resolution of the azygos vein thrombosis. A wide variety of infections can be associated with thrombotic events in patients with transient antiphospholipid syndrome (APS), and this case serves as a reminder that the possibility of transient APS should be considered in patients with venous thrombosis in the setting of a UTI.

Keyword

Antiphospholipid syndrome; Urinary tract infections; Escherichia coli

MeSH Terms

Aged
Antibodies, Anticardiolipin
Antibodies, Antiphospholipid
Antiphospholipid Syndrome*
Azygos Vein*
Escherichia coli*
Escherichia*
Female
Femur
Humans
Immunoglobulin M
Thorax
Thrombosis
Urinary Tract Infections*
Urinary Tract*
Venous Thrombosis
Antibodies, Anticardiolipin
Antibodies, Antiphospholipid
Immunoglobulin M

Figure

  • Figure 1. Contrast enhanced chest computed scan, axial image at pulmonary trunk bifurcation and coronal reformation, showed filling defects in the azygos vein (arrows).

  • Figure 2. Follow-up of chest computed tomography revealed complete resolution of the embolism in the azygos vein (arrows).


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