J Korean Ophthalmol Soc.  2007 May;48(5):731-736.

A Case of Solitary Bone Plasmacytoma Presenting with Erythematous Swelling of the Upper Eyelid

• Kim KH
• Oh DE
• Kim YD

Abstract

PURPOSE: To demonstrate a rare case of orbital solitary bone plasmacytoma that presented with erythematous swelling of the upper eyelid.
METHODS
A 64-year-old woman presented with a erythematous swelling of the right upper eyelid that persisted for 8 months prior to examination. There were 3 mm of proptosis in the right eye on ophthalmologic examination and an orbital tumor was detected on computed tomography (CT) scan, infiltrating the intracranial space and the sphenoid bone. Therefore, we performed incisional biopsy through the right upper eyelid.
RESULTS
Histopathologic examination revealed the tumor to be a plasmacytoma (lambda light chain-type) and all the systemic work-ups (serologic and urinary protein immunoelectrophoresis, bone marrow biopsy, radiologic examination) to rule out multiple myeloma were negative. Because of these factors, a diagnosis of solitary bone plasmacytoma was made. Radiation therapy (5,000 Gy/25 fractions) was performed over 5 weeks and the size of the tumor was found to have markedly decreased on a follow-up CT scan.
CONCLUSIONS
Solitary bone plasmacytoma is rare and has variable prognoses. This condition should be considered when the presenting symptom is eyelid swelling and proptosis.

Keyword

Solitary bone plasmacytoma

MeSH Terms

Biopsy
Bone Marrow
Diagnosis
Exophthalmos
Eyelids*
Female
Follow-Up Studies
Humans
Immunoelectrophoresis
Middle Aged
Multiple Myeloma
Orbit
Plasmacytoma*
Prognosis
Sphenoid Bone
Tomography, X-Ray Computed