J Korean Neurosurg Soc.  2010 Aug;48(2):173-176. 10.3340/jkns.2010.48.2.173.

Undetermined Fibrous Tumor with Calcification in the Cerebellopontine Angle

• Cheon SH
• Kang SH
• Park KJ
• Chung YG

• KMID: 2138398
• DOI: http://doi.org/10.3340/jkns.2010.48.2.173

Abstract

In this report, we introduce an undetermined fibrous tumor with calcification occurring in the cerebellopontine angle (CPA). A 51-year-old woman was admitted with a short history of dizziness. Computed tomography and magnetic resonance images revealed a 2x2x2 cm sized mass at the left CPA which was round and calcified. There was no dura or internal auditory canal involvement. At surgery, the tumor was located at the exit of 7th and 8th cranial nerve complex. It was very firm, bright yellow and well encapsulated. Histologic findings revealed that the tumor was predominantly composed of fibrous component, scant spindle cells and dystrophic calcification. Immunohistochemical staining demonstrated positive for vimentin and negative for epithelial membrane antigen (EMA), S-100 protein, CD34, factor XIIIa and smooth muscle actin. The diagnosis was not compatible with meningioma, schwannoma, metastatic brain tumors, and other fibrous tumors. Although the tumor was resected in total, long term follow-up monitoring is necessary due to the possibility of recurrence.

Keyword

Calcification; Cerebellopontine angle; Immunohistochemistry; Tumor

MeSH Terms

Actins
Brain Neoplasms
Cerebellopontine Angle
Cranial Nerves
Dizziness
Factor XIIIa
Female
Follow-Up Studies
Humans
Immunohistochemistry
Magnetic Resonance Spectroscopy
Meningioma
Middle Aged
Mucin-1
Muscle, Smooth
Neurilemmoma
Recurrence
S100 Proteins
Vimentin
Actins
Factor XIIIa
Mucin-1
S100 Proteins
Vimentin