A Case of Giant Chondroid Syringoma with Unusual Clinical Features

Shin, Min Kyung; Lew, Bark Lynn; Sim, Woo Young

Abstract

Chondroid syringoma is an uncommon, benign and adnexal tumor which is composed of a mixture of epithelial cells and mesenchymal tissue. The usual presentation is of an asymptomatic, slowly growing mass, typically located in the head and neck region. We report a case of chondroid syringoma located in the right heel of a 46-year-old male patient. The tumor grew over a 10-year period, increasing rapidly in size over the last few months. It was a skin colored, 4.5x5x4 cm-sized, hyperkeratotic hard pedunculated nodule. The diagnosis of giant chondroid syringoma was made by clinical and histopathological examination, which showed a tubular structure and solid nest composed by more than two layers of epithelial cells embedded in a myxoid-adipoid tissue. The tubular lumina contained small amounts of amorphous, eosinophilic material. Regarding previous reports, this is a quite rare case of benign chondroid syringoma due to it's unusually large size and rare location.