Korean J Obstet Gynecol.  1999 Nov;42(11):2474-2479.

Screening of high risk pregnancy using maternal serum triple markers

• Im MW
• Han SH
• Park JH
• Oh KY
• Lim YK
• Song ES
• Kho SK
• Lee BI
• Kim JW
• Lee WY

Abstract

OBJECTIVE
Our purpose was to determine whether abnormal triple marker in the second trimester may be associated with adverse pregnancy outcomes.
METHODS
Between November 1996 and April 1998, we evaluated 1,158 pregnant women undergoing second trimester triple marker screening tests who delivered at our hospital. The pregnancy outcomes of 48 women with false positive screens were compared with 1,158 screen negative controls. The pregnancy outcomes were obtained from hospital delivery records. RESULTS: Women with abnormal triple marker showed increased risks for low birth weight(p<0.01). But there was no significant differences between study and control groups with respect to preterm labor, pregnancy induced hypertension, oligohydroamnios, premature rupture of membrane, placenta previa, abruptio placenta, fetal death in utero.
CONCLUSION
Abnormal triple marker in the second trimester was associated with low birth weight.

Keyword

Abnormal triple marker; False positive screens; Adverse pregnancy outcome

MeSH Terms

Female
Fetal Death
Humans
Hypertension, Pregnancy-Induced
Infant, Low Birth Weight
Infant, Newborn
Mass Screening*
Membranes
Obstetric Labor, Premature
Parturition
Placenta
Placenta Previa
Pregnancy
Pregnancy Outcome
Pregnancy Trimester, Second
Pregnancy, High-Risk*
Pregnant Women
Rupture