J Korean Neurosurg Soc.  2008 Mar;43(3):169-171. 10.3340/jkns.2008.43.3.169.

Giant Lymph Node Hyperplasia (Castleman's Disease) as a Rare Cause of Back Pain

• Kim KH
• Kim SD
• Kim SH
• Park JY

• KMID: 2067327
• DOI: http://doi.org/10.3340/jkns.2008.43.3.169

Abstract

Giant lymph node hyperplasia (Castleman's disease) is a nonneoplastic lymphoproliferative disorder of unknown etiology that usually occurs in the chest. Its morphological recognition is based on a composition of various histological features. The mass is often asymptomatic, but it can cause nonspecific thoracic symptoms, such as regional pain. This disease can be found wherever lymph nodes are present, but two-thirds of these tumors are found in the chest, along the tracheobronchial tree in the mediastinum or lung hilus. However, we experienced an unusual case of Castleman's disease as a cause of back pain that was localized in the posterior mediastinum bordering the chest wall.

Keyword

Castleman's disease; Giant lymph node hyperplasia; Hyaline vascular type; Mediastinum; Back pain

MeSH Terms

Back Pain
Giant Lymph Node Hyperplasia
Lung
Lymph Nodes
Lymphoproliferative Disorders
Mediastinum
Thoracic Wall
Thorax