Chonnam Med J.  1998 Dec;34(2):309-318.

A Clinical Observation on Sheehan's Syndrome

Affiliations
  • 1Department of Internal Medicine, Chonnam University Medical School, Kwangju, Korea.

Abstract

Twenty four patients with Sheehan's syndrome were studied with high-resolution sella computed tomography(CT) or magnetic resonance imaging(MRI) and the se- quential pituitary stimulation test in order to correlate the radiologic findings of sella turcica with pituitary reserve functions. Radiologic imaging revealed 18 completely empty sella(CES), 5 partially empty sella (PES) and 1 normal sella. Panhypopituitarism occured in 1 patient with normal sella, 4 of 5 patient with PES and 11 of 18 patients with CES after combined pituitary stimulation. We found no correlation between the presence of pituitary tissue in sella CT or MRI evaluation and preservation of the function in the study on Sheehan's syndrome. There was no other apparent difference in clinical presentation and severity, chronological course of illness and hormonal parameters between patients having complete and partial ES.

Keyword

Sheehan's syndome; CT; MRI; Pituitary function

MeSH Terms

Humans
Hypopituitarism*
Magnetic Resonance Imaging
Sella Turcica
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