Korean J Dermatol.  2013 Jan;51(1):13-20.

Study on the Comparison between Wide Excision and Mohs Micrographic Surgery for the Management of Dermatofibrosarcoma Protuberans: A Single Institution Experience

Affiliations
  • 1Department of Dermatology, Chonbuk National University Medical School, Jeonju, Korea. dermayun@jbnu.ac.kr
  • 2Department of Plastic and Reconstructive Surgery, Chonbuk National University Medical School, Jeonju, Korea.
  • 3Research Institute of Clinical Medicine, Chonbuk National University Medical School, Jeonju, Korea.

Abstract

BACKGROUND
Dermatofibrosarcoma protuberans is a mesenchymal tumor of the skin of intermediate-grade which is a rare condition. The slow growing and aggressive invasion on local tissues are characteristic features of dermatofibrosarcoma protuberans. The treatment for dermatofibrosarcoma protuberans is mainly a surgical excision such as a wide excision and Mohs micrographic surgery.
OBJECTIVE
The aim of this study was to compare the result of wide excision and Mohs micrographic surgery for the treatment of dermatofibrosarcoma protuberans at a single institution in Korea.
METHODS
A retrospective review was done for 24 patients diagnosed with dermatofibrosarcoma protuberans and treated surgically from 1999 to 2010 at Chonbuk National University Hospital. Patient demographics, tumor features, surgical features, and recurrence during the follow-up period were evaluated.
RESULTS
13 patients were treated with wide excision, and 11 with Mohs micrographic surgery. There was no metastasis for all the cases. Mean operation time for the wide excision group was 83 minutes whereas 182 minutes for the Mohs micrographic surgery group, and it was a statistically significant difference. However, no significant difference was observed in post-operative defect size, advanced surgical repair and local recurrence in our study.
CONCLUSION
We suggest that wide excision and Mohs micrographic surgery are both successful modalities for the surgical treatment of dermatofibrosarcoma protuberans. Hence, individualized patient and tumor characteristics should be concerned when determining the surgical options for dermatofibrosarcoma protuberans.

Keyword

Dermatofibrosarcoma protuberans; Mohs micrographic surgery; Wide excision

MeSH Terms

Demography
Dermatofibrosarcoma
Follow-Up Studies
Humans
Mohs Surgery
Neoplasm Metastasis
Recurrence
Retrospective Studies
Skin
Dermatofibrosarcoma
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