Korean J Oral Maxillofac Radiol.
2000 Dec;30(4):287-292.
Dento-maxillofacial abnormalities caused by radiotherapy and chemotherapy
- Affiliations
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- 1Department of Oral and Maxillofacial Radiology, College of Dentistry, Kyung Hee University, Korea. hehan@khu.ac.kr
Abstract
- A case of dento-maxillofacial abnormality involving a 10-year-old male patient with a history of esthesioneuroblastoma is presented. This patient had been treated with 54 Gy (60)Co-gamma-radiation to the nasal cavity for 6 weeks and 6 cycles of combination chemotherapy of Cyclophosphamide, Cisplatin, Adriamycin, VM-26 (Teniposide), and DTIC (Dacarbazine) when he was 16 months of age. Five years after cessation of cancer therapy, he was disease free and transferred for extensive dental care to Kyung Hee University Dental Hospital. A clinical and radiologic follow-up over last 4 years showed root stunting, premature closure of the root apices, microdontia, developmental arrest, small crowns, and partial anodontia. Maxillofacial morphology evaluated by cephalometric analysis showed deficiency of maxillary development.
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