Korean J Vet Res.  2013 Jun;53(2):129-131.

Effect of clomipramine in a dog with cataplexy

Affiliations
  • 1Department of Veterinary Internal Medicine, College of Veterinary Medicine, Konkuk University, Seoul 143-701, Korea. parkhee@konkuk.ac.kr

Abstract

A 5-year-old, castrated male, Maltese was presented with history of acute flaccid paralysis. The dog was presented with sudden loss of muscle tone and involuntary movements of hind limbs. Neurologic examination revealed reduced postural reaction in the bilateral hind limbs. MRI of brain showed moderate hydrocephalus, but other examination results were normal. Based on the characteristic episodes and examination results, canine cataplexy was suspected. Treatment was initiated with clomipramine as cataplexy control. Clinical signs resolved with 3-month medication. This case demonstrates therapeutic diagnosis of cataplexy. To the author's knowledge, this is the first report of cataplexy treating with clomipramine.

Keyword

cataplexy; clomipramine; narcolepsy

MeSH Terms

Animals
Brain
Cataplexy
Clomipramine
Dogs
Dyskinesias
Extremities
Humans
Hydrocephalus
Male
Muscles
Narcolepsy
Neurologic Examination
Paralysis
Clomipramine
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