Prophylactic Measure of Urinary Infection in Transurethral Resection

Lee, Chong Koo; Lee, Eun Sik; Lee, Chongwook

Abstract

Three hundred and fifteen patients who underwent transurethral resection for bladder tumor and BPH were divided into 5 groups according to prophylactic measures. Patients with non-bacteriuria preoperatively were treated with short-term or long-term antibiotics or bladder irrigation with chlorhexidine. Patients with bacteriuria preoperatively were treated with either short-term or long-term antibiotics. In short-term antibiotics groups, cefazoline (2.0gm) were given twice a day from preoperative night to the day of catheter-removal. Oral antibiotics for 1-2 weeks were administered to the patients in long-term antibiotics groups. In irrigation groups, bladder was irrigated with 100ml of chlorhexidine solution every 2 hours postoperatively for one day, then every 6 hours until the day of catheterremoval. Several factors that might have influenced postoperative infection were comparable in each groups (p>0.06, by Student-t test). There were no significant differences in the incidence of postoperative bacteriuria among each groups(p>0.05, by x2-test) There was no systemic or local side effects of chlorhexidine except one patient who complained chilling sensation during instillation of chlorhexidine. These results indicates that irrigation of bladder with chlorhexidine is effective in the prevention of postoperative infection after transurethral resection in patients with nonbacteuria preoperatively, and short-term antibiotics treatment is as effective as longterm treatment in patients with preoperative bacteriuria.