Ewha Med J.  1978 Dec;1(4):283-287. 10.12771/emj.1978.1.4.283.

An Experimental Study about the Effect of Local Anesthesia on Skin Flap Survival

Affiliations
  • 1Department of Plastic Surgery, College of Medicine, Ewha Womans University, Korea.

Abstract

Despite the wide use of local anesthetics in surgery, relatively little has been proven about the effects of these agents on skin flaps. The following investigation was undertaken to study the influence of local anesthetic agents, which and without epineprine, on the survival of skin flaps in the rabbits. Infiltration with xylocaine or procaine alone had no influence on the viability of either nondelayed or delayed flaps. However, the addition of 1:100,000 epinephrine, which was not detrimental to survival length in nondelayed flaps, significantly reduced the surviving length in delayed skin flaps.


MeSH Terms

Anesthesia, Local*
Anesthetics
Anesthetics, Local
Epinephrine
Lidocaine
Procaine
Rabbits
Skin*
Anesthetics
Anesthetics, Local
Epinephrine
Lidocaine
Procaine
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