J Korean Ophthalmol Soc.  1964 Nov;5(2):63-65.

The Effect of Alpha-chymotrypsin, Trypsin and Hyaluronidase on the Viscosity of the Rabbit's Vitreous Humor

Affiliations
  • 1Department of Ophthalmology, College of Medicine, Seoul National University, Korea.

Abstract

Alpha-chymotrypsin, trypsin and hyaluronidase were added to the rabbit's vitreous humor which was filtered through the glass filter. The viscosity was measured by Ostwald type viscosimeter with O.5mm capillary bore size. The relative viscosity of normal vitreons humor was 1.085. The relative viscosities of vitreous humor, to which 1mg and 2mg of alpha-chymotrypsin and 100 H.U.M. and 200 H.U.M. of trypsin were added, showed no significant changes. On the other hand, the vitreous humor which had been treated by 100 T.R.U. of hyaluronidase showed a marked reduction in the viscosity. The viscosity of normal vitreous humor, which had been preserved at 20 degrees for 3 hours, was significantly reduced.


MeSH Terms

Capillaries
Glass
Hand
Hyaluronoglucosaminidase*
Trypsin*
Viscosity*
Vitreous Body*
Hyaluronoglucosaminidase
Trypsin
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