Korean J Ophthalmol.  2010 Dec;24(6):364-366. 10.3341/kjo.2010.24.6.364.

Orbital Metastatic Angiosarcoma

• Hassane S
• Fouad E
• Said I
• Karim R
• Asmae N
• Houcine C
• Abdelbar O

• KMID: 1769091
• DOI: http://doi.org/10.3341/kjo.2010.24.6.364

Abstract

We report a case of a 48-year-old man who developed metastatic angiosarcoma in her left orbit. A 48-year-old man was first sent to us for a check up of proptosis of the left eye. A left orbital tumor was recognized on orbital computed tomography scans. The open biopsy showed angiosarcoma. Chest X-ray films and thoracic computed tomography showed an abnormal mass in the left inferior lung field. Angiosarcoma was confirmed by transbronchial lung biopsy. In summary, we believed that the orbital tumour was an initial symptom of the metastasis ensuing from the lung angiosarcoma.

Keyword

Hemangiosarcoma; Orbital metastasis

MeSH Terms

Antineoplastic Agents/administration & dosage
Antineoplastic Agents, Phytogenic/administration & dosage
Antineoplastic Combined Chemotherapy Protocols/therapeutic use
Brain Neoplasms/pathology/secondary
Cisplatin/administration & dosage
Etoposide/administration & dosage
Fatal Outcome
Hemangiosarcoma/pathology/radiography/radiotherapy/*secondary/therapy
Humans
Lung Neoplasms/drug therapy/*pathology/radiography
Male
Middle Aged
Orbital Neoplasms/pathology/*radiography/*secondary
Tomography, X-Ray Computed

Figure

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  Fig. 1 Left orbital proptosis with chemosis.

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  Fig. 2 Coronal computed tomography shows a superior orbital mass with bony destruction and brain extended.

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  Fig. 3 Chest computed tomography showing a left lung tumor.

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  Fig. 4 Orbital metastasis of bronchial angiosarcoma (H&E, ×200).

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  Fig. 5 Tumoral cells are staining by factor VIII.

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  Fig. 6 Tumoral cells are marking with CD31 factor.

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  Fig. 7 Important leap of inflammatory oedema of the orbit after biopsy.

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  Fig. 8 Bronchial mucosa showed lumina lined by sarcomatous cells (H&E, ×200).

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