Pediatr Allergy Respir Dis.
2001 Mar;11(1):67-71.
A Case of Mastocytosis in Three-month-old Female Infant
- Affiliations
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- 1Department of Pediatrics, College of Medicine, Yonsei University, Seoul, Korea.
- 2Department of Dermatology, College of Medicine, Yonsei University, Seoul, Korea.
Abstract
- Mastocytosis is rare disorder characterized by the overproliferation and accumulation of tissue mast cells and spontaneous regression before adolescence in childhood, almost. Clinical features are vary and depend on local accumulation of mast cells in different organs and the effects of their mediators. Mast cell disease is commonly involved in the skin, and occasionally gastrointestinal tract, bone marrow, liver, spleen and lymphoid organs as well. Mastocytosis occurs equally in persons of each gender and it affects all age groups. The incidence is unknown and familial tendency is unusual. We are reporting a case of mastocytosis confirmed by skin biopsy who was visited for skin lesions that skin rashes at 10 days after birth, change to bullar at 3 month later.