Infect Chemother.  2010 Aug;42(4):241-243. 10.3947/ic.2010.42.4.241.

A Case of Arcanobacterium haemolyticum Bacteremia and Osteomyelitis Diagnosed by 16s rRNA Sequencing

• Bae SY
• Choi S
• Kang SJ
• Jang HC
• Park KH
• Jung SI
• Shin JH

• KMID: 1457385
• DOI: http://doi.org/10.3947/ic.2010.42.4.241

Abstract

Arcanobacterium haemolyticum is a catalase-negative, aerobic gram-positive rod. It causes pharyngitis, skin and soft tissue infection, osteomyelitis, endocarditis, meningitis, pneumonia, and septicemia. We experienced a case of A. haemolyticum bacteremia and osteomyelitis in a diabetic patient. The organism was misidentified as Cellulomonas species by automated system but correctly identified as A. haemolyticum by 16s rRNA sequencing.

Keyword

Arcanobacterium; Bacteremia; Sequence analysis; RNA

MeSH Terms

Arcanobacterium
Bacteremia
Cellulomonas
Endocarditis
Humans
Meningitis
Osteomyelitis
Pharyngitis
Pneumonia
RNA
Sepsis
Sequence Analysis
Skin
Soft Tissue Infections
RNA

Figure

• 

  Figure 1 Findings of osteomyelitis in tri-phase bone scan. Bony uptake of left 1st proximal and distal phalanges is not observed in delayed phase image. Increased uptakes of left 1st metatarsal bone head, tarsal bone, and upper portion of calcaneous are observed in delayed phase image.

• 

  Figure 2 Reverse CAMP test. Arcanobacterium haemolyticum is streaked horizontally and Staphylococcus aureus ATCC 26923 was streaked vertically. The inhibition zone of hemolysis of Staphylococcus ATCC 25923 is noted near the streak line of Arcanobacterium haemolyticum.

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