- Construction of a live attenuated Salmonella strain expressing FanC protein to prevent bovine enterotoxigenic Escherichia coli and evaluation of its immunogenicity in mice
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Won G, Kim HJ, Lee JH
- KMID: 2376873
- Korean J Vet Res.
- 2017 Mar;57(1):9-15.
- doi: 10.14405/kjvr.2017.57.1.9
To construct a novel vaccine candidate against bovine enterotoxigenic Escherichia coli (ETEC), FanC, the major subunit of K99 fimbriae adhesion, was inserted into secretion plasmid pYA3560 containing a β-lactamase secretion... -
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- The association between dependent self-employment and self-reported depression/anxiety and sleep disorder in South Korea
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Won G, Park JB, Lee KJ, Ha R, Lee S, Jeong I
- KMID: 2466057
- Ann Occup Environ Med.
- 2019 ;31(1):e13.
- doi: 10.35371/aoem.2019.31.e13
BACKGROUND: Dependent self-employment is precarious employment, which can be vulnerable to mental health problems. This study aimed to investigate the association of dependent self-employment with depression, anxiety, and sleep disorder... -
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- Hens immunized with live attenuated Salmonella strains expressing virulence-associated genes in avian pathogenic Escherichia coli passively transfer maternal antibodies to chicks
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Won G, Lee JH
- KMID: 2368763
- Korean J Vet Res.
- 2016 Sep;56(3):167-176.
- doi: 10.14405/kjvr.2016.56.3.167
We investigated whether maternal antibodies (mAbs) elicited by dams immunized with recombinant vaccine candidates against avian pathogenic Escherichia coli (APEC) can passively confer protective immunity to chicks. In the present... -
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- A Salmonella Typhi ghost induced by the E gene of phage φX174 stimulates dendritic cells and efficiently activates the adaptive immune response
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Won G, Eo SK, Park SY, Hur J, Lee JH
- KMID: 2417569
- J Vet Sci.
- 2018 Jul;19(4):536-542.
- doi: 10.4142/jvs.2018.19.4.536
Previously, we genetically engineered a Salmonella Typhi bacterial ghost (STG) as a novel inactivated vaccine candidate against typhoid fever. The underlying mechanism employed by the ghost in stimulating the adaptive... -
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- Effect of immunization routes and protective efficacy of Brucella antigens delivered via Salmonella vector vaccine
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Lalsiamthara J, Won G, Lee JH
- KMID: 2412132
- J Vet Sci.
- 2018 May;19(3):416-425.
- doi: 10.4142/jvs.2018.19.3.416
An anti-Brucella vaccine candidate comprised of purified Brucella lipopolysaccharide (LPS) and a cocktail of four Salmonella Typhimurium (ST)-Brucella vectors was reported previously. Each vector constitutively expressed highly conserved Brucella antigens... -
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- Loss of Neutralizing Activity of Tixagevimab/Cilgavimab (Evusheld™) Against Omicron BN.1, a Dominant Circulating Strain Following BA.5 During the Seventh Domestic Outbreak in Korea in Early 2023
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Yang J, Hyeon S, Baek JY, Kang MS, Lee KY, Lee YH, Huh K, Cho SY, Kang CI, Chung DR, Peck KR, Won G, Lee HW, Kim K, Hwang I, Lee SY, Kim BC, Lee Yk, Ko JH
- KMID: 2544411
- J Korean Med Sci.
- 2023 Jul;38(27):e205.
- doi: 10.3346/jkms.2023.38.e205
Tixagevimab/cilgavimab is a monoclonal antibody used to prevent coronavirus disease 2019 among immunocompromised hosts and maintained neutralizing activity against early omicron variants. Omicron BN.1 became a dominant circulating strain in... -
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- Effects of changes in occupational stress on the depressive symptoms of Korean workers in a large company: a longitudinal survey
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Jung J, Jeong I, Lee KJ, Won G, Park JB
- KMID: 2428605
- Ann Occup Environ Med.
- 2018 ;30(1):39.
- doi: 10.1186/s40557-018-0249-5
BACKGROUND: Prospective studies on occupational stress and depression among Korean workers are scarce. This study aimed to investigate the causal relationship between changes in occupational stress and the presence of... -
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- An attenuated Salmonella vaccine secreting Lawsonia intracellularis immunogenic antigens confers dual protection against porcine proliferative enteropathy and salmonellosis in a murine model
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Park S, Won G, Lee JH
- KMID: 2448708
- J Vet Sci.
- 2019 May;20(3):e24.
- doi: 10.4142/jvs.2019.20.e24
Porcine proliferative enteropathy (PPE) caused by Lawsonia intracellularis (LI) is a global cause for substantial economic losses in the swine industry. Here, we constructed live attenuated Salmonella typhimurium (ST) mutant... -
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- Protective efficacy and immune responses by homologous prime-booster immunizations of a novel inactivated Salmonella Gallinarum vaccine candidate
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Won G, Chaudhari , Lee JH
- KMID: 2421562
- Clin Exp Vaccine Res.
- 2016 Jul;5(2):148-158.
- doi: 10.7774/cevr.2016.5.2.148
PURPOSE: Salmonella enterica serovar Gallinarum (SG) ghost vaccine candidate was recently constructed. In this study, we evaluated various prime-boost vaccination strategies using the candidate strain to optimize immunity and protection... -
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