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Analysis of the distribution of trial sites in South Korea using social network analysis

Huh KY, Yu KS, Song I

Location of trial sites can be a potential source of study bias. Considering that clinical trials have been mostly conducted in urban areas, the distribution of trial sites need to...
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Effects of three-dimensional image based insole for healthy volunteers: a pilot clinical trial

Jeong BO, Jeong SJ, Park K, Kim BH, Yim SV, Kim S

Insoles are used to treat various foot diseases, including plantar foot, diabetic foot ulcers, and refractory plantar fasciitis. In this study, we investigated the effects of 3-dimensional image-based (3-D) insole...
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Evaluation of pharmacokinetic interactions between lobeglitazone, empagliflozin, and metformin in healthy subjects

Kim H, Kim CO, Park H, Park MS, Kim D, Hong T, Shin Y, Jin BH

Concomitant administration of lobeglitazone, empagliflozin, and metformin is expected to enhance blood glucose-lowering effects and improve medication compliance in patients with diabetes mellitus. In this study, we investigated the pharmacokinetic...
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Size-reduced fexuprazan 20 mg demonstrated the optimal bioavailability and bioequivalence with the reference formulation

Yang AY, Yoo H, Shin W, Lee YS, Lee H, Kim SE, Kim A

Fexuprazan (DWP14012), a potassium-competitive acid blocker, is a medical formulation prescribed to inhibit the secretion of gastric acid. The present study encompasses a comparative evaluation of pharmacokinetic (PK) analysis between...
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Efficacy and safety assessment of protein supplement - micronutrient fortification in promoting health and wellbeing in healthy adults -a randomized placebo-controlled trial

Ambulkar P, Hande P, Tambe B, Vaidya VGV, Naik N, Agarwal R, i Ganu G

Protein supplements are extensively used for muscle building, weight loss, recovery from exercise, improving endurance & cardio-performance. Major challenge with protein supplement is undigested protein and impaired gut health which...
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Impact of antioxidants in improving semen parameters like count, motility and DNA fragmentation in sub-fertile males: a randomized, double-blind, placebo-controlled clinical trial

Patki A, Shelatkar R, Singh M, Agarwal S, M V, Umbardand S, Reddy A, Kannan P, Gorthi S, Khastgir G, Kulshreshtha A, Ganu G

Male infertility is solely responsible for 20–30% of infertility cases. Oxidative damage of sperm DNA is positively linked with oligoasthenoteratozoospermia (OAT), and male infertility. The antioxidants are being explored worldwide...
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