- Adequacy of safety data for regulatory approval of pediatric indication through extrapolation algorithm
-
Park MS
- KMID: 2525611
- Transl Clin Pharmacol.
- 2021 Jun;29(2):73-77.
- doi: 10.12793/tcp.2021.29.e11
no abstract available. -
- CITED
-
- Close
- SHARE
-
- Close
- Acetaminophen-induced anaphylaxis: a case report
-
Sunwoo J, Kim H, Bae KS
- KMID: 2525609
- Transl Clin Pharmacol.
- 2021 Jun;29(2):88-91.
- doi: 10.12793/tcp.2021.29.e8
Acetaminophen is known to be generally safe, and the occurrence of anaphylaxis due to acetaminophen has been rarely reported. We report a case of acetaminopheninduced anaphylaxis in a healthy male... -
- CITED
-
- Close
- SHARE
-
- Close
- Predicting human pharmacokinetics from preclinical data: clearance
-
Yim DS, Bae SH, Choi S
- KMID: 2525610
- Transl Clin Pharmacol.
- 2021 Jun;29(2):78-87.
- doi: 10.12793/tcp.2021.29.e12
We have streamlined known in vitro methods used to predict the clearance (CL) of small molecules in humans in this tutorial. There have been many publications on in vitro methods... -
- CITED
-
- Close
- SHARE
-
- Close
- Associations between HLA-A, -B, and -C alleles and iodinated contrast media– induced hypersensitivity in Koreans
-
Kim EY, Choi SJ, Ghim JL, Kim MY, Seol JE, Oh M, Park CS, Shin JG
- KMID: 2525607
- Transl Clin Pharmacol.
- 2021 Jun;29(2):107-116.
- doi: 10.12793/tcp.2021.29.e10
A common cause of drug hypersensitivity reactions is iodinated contrast media (ICM). ICM-induced hypersensitivity had been considered to be a non-immunological reaction, but evidence for an immunological mechanism has increased... -
- CITED
-
- Close
- SHARE
-
- Close
- Insulin sensitization causes accelerated sinus nodal dysfunction through autophagic dysregulation in hypertensive mice
-
Woo M, Kim M
- KMID: 2525608
- Transl Clin Pharmacol.
- 2021 Jun;29(2):92-106.
- doi: 10.12793/tcp.2021.29.e9
Insulin sensitizers, while effective in glucose-lowering for diabetes control, are linked to an increased risk of heart disease through mechanisms that are not well understood. In this study, we investigated... -
- CITED
-
- Close
- SHARE
-
- Close
