- Clinical development and trial operations in COVID-19 era
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Choe SC
- KMID: 2525618
- Transl Clin Pharmacol.
- 2021 Dec;29(4):181-185.
- doi: 10.12793/tcp.2021.29.e23
no abstract available. -
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- Trends of clinical trials from 2017 to 2019 in Korea: an integrated analysis based on the Ministry of Food and Drug Safety (MFDS) and the Clinical Research Information Service (CRIS) registries
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Huh KY, Yu KS, Lim HS, Kim H
- KMID: 2525619
- Transl Clin Pharmacol.
- 2021 Dec;29(4):186-196.
- doi: 10.12793/tcp.2021.29.e24
Public disclosure of approved clinical trials in a reliable registry can provide the transparency of the study. Although the registration of clinical trials has increased remarkably, the integrity of the... -
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- A validated simple LC-MS/MS method for quantifying trimethylamine N-oxide (TMAO) using a surrogate matrix and its clinical application
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Li Y, Kang J, Lee Y, Chung JY, Cho JY
- KMID: 2525622
- Transl Clin Pharmacol.
- 2021 Dec;29(4):216-225.
- doi: 10.12793/tcp.2021.29.e19
Trimethylamine N-oxide (TMAO) is a small molecular amine oxide generated from dietary choline and carnitine through intestinal microbial metabolism. Recently, TMAO has attracted much public attention as its role... -
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- Determination of candesartan or olmesartan in hypertensive patient plasma using UPLC-MS/MS
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Jeong HC, Seo YH, Gu N, Rhee MY, Shin KH
- KMID: 2525623
- Transl Clin Pharmacol.
- 2021 Dec;29(4):226-238.
- doi: 10.12793/tcp.2021.29.e21
Candesartan and olmesartan are angiotensin II receptor blockers (ARBs) used for the treatment of hypertension and heart failure. Quantitation methods for candesartan and olmesartan were developed using ultra-high performance liquid... -
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- QTc prolongation in patients with COVID-19: a retrospective chart review
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Pornwattanakavee SP, Priksri W, Leelakanok N
- KMID: 2525620
- Transl Clin Pharmacol.
- 2021 Dec;29(4):197-205.
- doi: 10.12793/tcp.2021.29.e20
Drug-induced corrected QT (QTc) prolongation can cause Torsade de Pointes (TdP) which leads to severe arrhythmia or sudden cardiac death. However, information on the prevalence of QTc prolongation in coronavirus... -
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- Medication selection for the treatment of acute infective diarrhea in Thai pharmacies: a qualitative study
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Leelakanok N, Petchsomrit A, Methaneethorn J, Pornwattanakavee SP
- KMID: 2525621
- Transl Clin Pharmacol.
- 2021 Dec;29(4):206-215.
- doi: 10.12793/tcp.2021.29.e22
World Health Organization (WHO) released the treatment manual of diarrhea in 2005. We aimed to investigate the rationale for selecting medications for acute infective diarrhea in Thai community pharmacies and... -
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