- Effect of CRP (cAMP Receptor Protein) of Escherichia coli on Transcription Initiation at lacUV5 Promoter
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Kim SY, Kwon H, Ryu S, Park C, Lee K
- KMID: 2146929
- J Korean Soc Microbiol.
- 1998 Aug;33(4):391-398.
The cyclic AMP receptor protein (CRP) complexed with cyclic AMP (CRP.cAMP) regulates expression of many genes by binding to sites at or near many promoters of Escherichia coli. The regulatory... -
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- Genomic Organization of ht eGene for Human Mig Chemokine
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Lee HH, Park KS
- KMID: 1557236
- Korean J Immunol.
- 1998 Dec;20(4):365-373.
"Mig is a gamma interferon-inducible T cell chemoattractant that is a member of the chemokine family of cytokines. In order to gain a better understanding of the molecular mechanisms that... -
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- Current Challenges in Bacterial Transcriptomics
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Cho S, Cho Y, Lee S, Kim J, Yum H, Kim SC, Cho BK
- KMID: 1494260
- Genomics Inform.
- 2013 Jun;11(2):76-82.
- doi: 10.5808/GI.2013.11.2.76
Over the past decade or so, dramatic developments in our ability to experimentally determine the content and function of genomes have taken place. In particular, next-generation sequencing technologies are now... -
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- The Association of Aldose Reductase Gene Polymorphisms with Neuropathy in Patients with Type 2 Diabetes
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Jeong IK, Park KS, Moon MK, Kim JH, Shin CS, Kim SY, Lee HK
- KMID: 1523016
- J Korean Diabetes Assoc.
- 2007 May;31(3):274-283.
- doi: 10.4093/jkda.2007.31.3.274
BACKGROUND: Previous studies have suggested that polymorphisms in and around the aldose reductase (AR) gene are associated with the development of diabetic microvascular disease. This study explored the hypothesis that... -
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- Transcriptional Regulation of the Xbr-1a/Xvent-2 Gene by BMP-4 Signaling during Xenopus Embryonic Development
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Kim JB, Lee HS, Roh DH, Hwang YS, Xu RH, Kung HF, Bae YC, Park MJ
- KMID: 2224548
- Korean J Anat.
- 2000 Oct;33(5):595-608.
BMP-4 signaling is mediated through Smad proteins which may translocate to the nucleus to activate transcription. Little is known about how BMP-4 signaling regulates the transcription of its target genes,... -
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- Early growth response protein 1 acts as an activator of SOX18 promoter
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Petrovic I, Kovacevic-Grujicic N, Stevanovic M
- KMID: 983986
- Exp Mol Med.
- 2010 Feb;42(2):132-142.
- doi: 10.3858/emm.2010.42.2.015
Sex-determining region Y box 18 (Sox18/SOX18) gene is an important regulator of vascular development playing a role in endothelial cell specification or differentiation, angiogenesis and atherogenesis. The aim of this... -
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- Genomic Organization of ancop Gene for alpha-COP Homolog from Aspergillus nidulans
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Lee HH, Chae SK, Kim JY, Maeng PJ, Park HM
- KMID: 2312327
- Mycobiology.
- 2000 Dec;28(4):171-176.
We have cloned a alpha-COP homolog, ancop, from Aspergillus nidulans by colony hybridization of chromosome specific library using alpha-COP homologous fragment as a probe. The probe DNA was amplified with... -
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- The Effect of Uteroglobin Exon 1, 5' Untranslated Region Polymorphism on the Progression of IgA Nephropathy
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Oh YK, Kwon DY, Zheng SH, Oh KH, Kim HL, Kim KS, Kim YS, Ahn C, Han JS, Kim S, Lee JS
- KMID: 2254480
- Korean J Nephrol.
- 2001 Jan;20(1):59-66.
Uteroglobin(UG) is an anti-inflammatory/immunomodulatory protein secreted by the epithelial cells of vertebrates. Targeted disruption of UG rendered mouse glomerulonephritis resembling IgA nephropathy(IgAN). Sequence analysis on exon 1 of UG showed... -
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- PromoterWizard: An Integrated Promoter Prediction Program Using Hybrid Methods
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Park K, Kim KB
- KMID: 2053276
- Genomics Inform.
- 2011 Dec;9(4):194-196.
Promoter prediction is a very important problem and is closely related to the main problems of bioinformatics such as the construction of gene regulatory networks and gene function annotation. In... -
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- HOTAIR Long Non-coding RNA: Characterizing the Locus Features by the In Silico Approaches
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Hajjari M, Rahnama S
- KMID: 2404055
- Genomics Inform.
- 2017 Dec;15(4):170-177.
- doi: 10.5808/GI.2017.15.4.170
HOTAIR is an lncRNA that has been known to have an oncogenic role in different cancers. There is limited knowledge of genetic and epigenetic elements and their interactions for the... -
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- Regulation of Vacuolar H+-ATPase c Gene Expression by Oxidative Stress
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Kwak WJ, Kim SM, Kim MS, Kang JH, Kim DJ, Kim HS, Kown OJ, Kim IK, Jeong SW
- KMID: 1600110
- Korean J Physiol Pharmacol.
- 2005 Oct;9(5):275-282.
By using differential display, we identified one of the genes encoding the multi-subunit complex protein V-ATPase, c subunit gene (ATP6L), and showed alterations of the gene expression by oxidative stresses.... -
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- Prostate stem cell antigen gene is expressed in islets of pancreas
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Ono H, Yanagihara K, Sakamoto H, Yoshida T, Saeki N
- KMID: 2046741
- Anat Cell Biol.
- 2012 Sep;45(3):149-154.
- doi: 10.5115/acb.2012.45.3.149
Prostate stem cell antigen (PSCA) is a glycosylphosphatidylinositol-anchored cell surface antigen with an organ-dependent expression pattern in cancers; e.g., up-regulated in prostate cancer and down-regulated in gastric cancer. Previously it... -
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- T Cell Immunoglobulin Mucin Domain (TIM)-3 Promoter Activity in a Human Mast Cell Line
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Kim JS, Shin DC, Woo MY, Kwon MH, Kim K, Park S
- KMID: 2150750
- Immune Netw.
- 2012 Oct;12(5):207-212.
- doi: 10.4110/in.2012.12.5.207
T cell immunoglobulin mucin domain (TIM)-3 is an immunomodulatory molecule and upregulated in T cells by several cytokines. TIM-3 also influences mast cell function but its transcriptional regulation in mast... -
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- Association of Polymorphic Regulatory Region of TIGR Gene with Glaucoma
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Koo HJ, Son S, Kee C
- KMID: 2205978
- J Korean Ophthalmol Soc.
- 2001 Mar;42(3):519-526.
PURPOSE: To identify the polymorphism in the regulatory region of trabecular meshwork inducible glucocorticoid response(TIGR) gene and evaluate the association of it with glaucoma. METHODS: 5'regulatory region of TIGR gene... -
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- Genomic organization and expression of parkin in Drosophila melanogaster
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Bae YJ, Park KS, Kang SJ
- KMID: 1093612
- Exp Mol Med.
- 2003 Oct;35(5):393-402.
We report here the isolation, characterization on genomic structure and expression of the D. melanogaster homolog of human parkin. The 2,122 bp parkin gene sequence contains six exons that form... -
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- IL-33 promotes IL-10 production in macrophages: a role for IL-33 in macrophage foam cell formation
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Zhang HF, Wu MX, Lin YQ, Xie SL, Huang TC, Liu PM, Nie RQ, Meng QQ, Luo NS, Chen YX, Wang JF
- KMID: 2396793
- Exp Mol Med.
- 2017 Nov;49(11):e388.
- doi: 10.1038/emm.2017.183
We evaluated the role of IL-10- in IL-33-mediated cholesterol reduction in macrophage-derived foam cells (MFCs) and the mechanism by which IL-33 upregulates IL-10. Serum IL-33 and IL-10 levels in coronary... -
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- Association of(G-T)n Dinucleotide Repeat Polymorphism of 5'-Flanking Region of TIGR/MYOC with Normal-Tension Glaucoma and Steroid-Induced Glaucoma
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Cho CH, Hur WH, Kee C
- KMID: 2125029
- J Korean Ophthalmol Soc.
- 2001 Jun;42(6):889-892.
PURPOSE: We investigated whether TIGR/MYOC, a candidate gene for the primary open angle glaucoma(POAG) is also involved in the pathogenesis of normal tension glaucoma(NTG) and steroid-induced glau-coma(SIG). METHODS: Genomic DNA... -
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- DNA Methylation and Expression Patterns of Key Tissue-specific Genes in Adult Stem Cells and Stomach Tissues
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Hong SJ, Kang MI, Oh JH, Jung YC, Kim YH, Kim SJ, Choi SH, Seo EJ, Choi SW, Rhyu MG
- KMID: 1782016
- J Korean Med Sci.
- 2009 Oct;24(5):918-929.
- doi: 10.3346/jkms.2009.24.5.918
CpG-island margins and non-island-CpG sites round the transcription start sites of CpG-island-positive and -negative genes are methylated to various degrees in a tissue-specific manner. These methylation-variable CpG sites were analyzed... -
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- Aberrant epigenetic regulation of GABRP associates with aggressive phenotype of ovarian cancer
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Sung HY, Yang SD, Ju W, Ahn JH
- KMID: 2382697
- Exp Mol Med.
- 2017 May;49(5):e335.
- doi: 10.1038/emm.2017.62
Metastasis is a major cause of therapeutic failure in ovarian cancer. To elucidate molecular mechanisms of ovarian cancer metastasis, we previously established a metastatic xenograft mouse model using human ovarian... -
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- Single Nucleotide Polymorphisms of Interleukin-10 Promoter Gene in Korean Herpes Zoster Patients
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Park SJ, Cho JW, Lee KS
- KMID: 2087192
- Korean J Dermatol.
- 2006 Nov;44(11):1325-1331.
BACKGROUND: Herpes zoster is a common viral infectious disease that is caused by the varicellar zoster virus (VZV). It has been suggested that impaired cellular immunity is responsible for the reactivation... -
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