- Aggressive Supratentorial Ependymoma, RELA Fusion-Positive with Extracranial Metastasis: A Case Report
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Kim SI, Lee Y, Kim SK, Kang HJ, Park SH
- KMID: 2396542
- J Pathol Transl Med.
- 2017 Nov;51(6):588-593.
- doi: 10.4132/jptm.2017.08.10
Ependymoma is the third most common pediatric primary brain tumor. Ependymomas are categorized according to their locations and genetic abnormalities, and these two parameters are important prognostic factors for patient... -
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- Subcellular localization of nuclear factor kappa B in term human fetal membranes and myometrium during labor
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Choi SJ, Moon SO, Kim HS, Oh SY, Roh CR, Kim JH
- KMID: 2272755
- Korean J Obstet Gynecol.
- 2006 Jan;49(1):24-30.
OBJECTIVE: To investigate the subcellular localization of nuclear factor kappa B (NF-kappa B) in term human fetal membranes and myometrium during labor. METHODS: Fetal membranes and myometrial tissue were collected from... -
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- The Role of Nuclear Factor Kappa B on Lens Epithelial Cells after Ultraviolet B Irradiation
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Lee DH, Kim JK, Oh SH, Kim EK, Joo CK
- KMID: 1902563
- J Korean Ophthalmol Soc.
- 2004 Mar;45(3):500-506.
PURPOSE: This study was performed to determine the role of nuclear factor kappa B (NF-kappa B) on the lens epithelial cell death after ultraviolet (UV) irradiation. METHODS: Simian virus 40... -
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- Thalidomide Accelerates the Degradation of Extracellular Matrix in Rat Hepatic Cirrhosis via Down-Regulation of Transforming Growth Factor-beta1
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Lv P, Meng Q, Liu J, Wang C
- KMID: 2345885
- Yonsei Med J.
- 2015 Nov;56(6):1572-1581.
- doi: 10.3349/ymj.2015.56.6.1572
PURPOSE: The degradation of the extracellular matrix has been shown to play an important role in the treatment of hepatic cirrhosis. In this study, the effect of thalidomide on the... -
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- Inhibition of miR-128 Abates Aβ-Mediated Cytotoxicity by Targeting PPAR-γ via NF-κB Inactivation in Primary Mouse Cortical Neurons and Neuro2a Cells
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Geng L, Zhang T, Liu W, Chen Y
- KMID: 2422495
- Yonsei Med J.
- 2018 Nov;59(9):1096-1106.
- doi: 10.3349/ymj.2018.59.9.1096
PURPOSE: Alzheimer's disease (AD) is the sixth most common cause of death in the United States. MicroRNAs have been identified as vital players in neurodegenerative diseases, including AD. microRNA-128 (miR-128)... -
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- A new synthetic chalcone derivative, 2-hydroxy-3',5,5'-trimethoxychalcone (DK-139), suppresses the Toll-like receptor 4-mediated inflammatory response through inhibition of the Akt/NF-kappaB pathway in BV2 microglial cells
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Lee YH, Jeon SH, Kim SH, Kim C, Lee SJ, Koh D, Lim Y, Ha K, Shin SY
- KMID: 1383799
- Exp Mol Med.
- 2012 Jun;44(6):369-377.
Microglial cells are the resident innate immune cells that sense pathogens and tissue injury in the central nervous system (CNS). Microglial activation is critical for neuroinflammatory responses. The synthetic compound... -
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- Cobalt Chloride Attenuates Oxidative Stress and Inflammation through NF-kappaB Inhibition in Human Renal Proximal Tubular Epithelial Cells
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Oh SW, Lee YM, Kim S, Chin HJ, Chae DW, Na KY
- KMID: 2069805
- J Korean Med Sci.
- 2014 Sep;29(Suppl 2):S139-S145.
- doi: 10.3346/jkms.2014.29.S2.S139
We evaluated the effect of cobalt chloride (CoCl2) on TNF-alpha and IFN-gamma-induced-inflammation and reactive oxygen species (ROS) in renal tubular epithelial cells (HK-2 cells). We treated HK-2 cells with CoCl2... -
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- The role of Bcl-xL and nuclear factor-kappaB in the effect of taxol on the viability of dendritic cells
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Kim MH, Joo HG
- KMID: 1102965
- J Vet Sci.
- 2009 Jun;10(2):99-103.
- doi: 10.4142/jvs.2009.10.2.99
Taxol has been used effectively in cancer therapies. Our previous study demonstrated that taxol induced altered maturation and improved viability of dendritic cells (DCs). However, the effects of taxol on... -
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- Immunohistochemical Analysis of Nuclear Factor, p38, and Cyclin D1 Proteins in Premalignant Lesions and Carcinomas of the Colorectal Mucosa
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Lee SD, Lee TJ, Park ES
- KMID: 783112
- Korean J Gastroenterol.
- 2008 Dec;52(6):359-367.
BACKGROUND/AIMS: Nuclear factor-kappa B p65 (NF-kappa B p65), nuclear factor-kappa B1 p50 (NF-kappa B p50) have been shown to play a role in cell proliferation, apoptosis, cytokine production, and oncogenesis.... -
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- The orphan nuclear receptor SHP inhibits apoptosis during the monocytic differentiation by inducing p21WAF1
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Kim K, Choi YH, Kim HH, Cheong J
- KMID: 756235
- Exp Mol Med.
- 2009 Jun;41(6):429-439.
- doi: 10.3858/emm.2009.41.6.048
Small heterodimer partner (SHP) is an atypical member of nuclear receptor superfamily that lacks a DNA-binding domain. In previous study, we showed that SHP, c-jun, p65 of NF-kappaB subunits, and... -
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- NF-kappaB Binding Activity and Cyclooxygenase-2 Expression in Persistent betaCCI(4)-Treated Rat Liver Injury
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Kim SH, Chu HJ, Kang DH, Song GA, Cho M, Yang US, Kim HJ, Chung HY
- KMID: 648675
- J Korean Med Sci.
- 2002 Apr;17(2):193-200.
- doi: 10.3346/jkms.2002.17.2.193
The involvement of NF-kappaB binding activity is known to be important in the mechanism of acute liver injury and in the induction of cyclooxygenase (COX-2). This study was performed to... -
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- The Effects of Family History of Colorectal Cancer on the Development of Colorectal Adenoma
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Choi MY, Kim BG, Kim JW, Lee KL, Jeong JB, Lee JK, Jung YJ, Kim W, Ahn DW, Kim YH, Joo SK, Chang MS, Kwon HJ
- KMID: 1718464
- Korean J Gastroenterol.
- 2012 Jul;60(1):36-41.
- doi: 10.4166/kjg.2012.60.1.36
BACKGROUND/AIMS: Early detection of polyp is important for the prevention of colorectal cancer (CRC). There have been few studies to investigate the relationship between colorectal adenoma and family history of... -
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- Potential role of HMG CoA reductase inhibitor on oxidative stress induced by advanced glycation endproducts in vascular smooth muscle cells of diabetic vasculopathy
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Yoon SJ, Yoon YW, Lee BK, Kwon HM, Hwang KC, Kim M, Chang W, Hong BK, Lee YH, Park SJ, Min PK, Rim SJ
- KMID: 1122281
- Exp Mol Med.
- 2009 Nov;41(11):802-811.
- doi: 10.3858/emm.2009.41.11.086
Advanced glycation endproducts (AGEs)-induced vascular smooth muscle cell (VSMCs) proliferation and formation of reactive oxygen species (ROS) are emerging as one of the important mechanisms of diabetic vasculopathy but little... -
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