- The Unreliability of MTT Assay in the Cytotoxic Test of Primary Cultured Glioblastoma Cells
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Jo HY, Kim Y, Park HW, Moon HE, Bae S, Kim J, Kim DG, Paek SH
- KMID: 2165560
- Exp Neurobiol.
- 2015 Sep;24(3):235-245.
- doi: 10.5607/en.2015.24.3.235
MTT assay is commonly used to assess the cellular cytotoxicity caused by anticancer drugs in glioblastomas. However, there have been some reports insisting that MTT assay exhibited non-specific intracellular reduction... -
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- Postoperative Adjuvant Radiotherapy for Patients with Gastric Adenocarcinoma
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Lim DH
- KMID: 2372450
- J Gastric Cancer.
- 2012 Dec;12(4):205-209.
In gastric adenocarcinoma, high rates of loco-regional recurrences have been reported even after complete resection, and various studies have been tried to find the role of postoperative adjuvant therapy. Among... -
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- Inhibition of cell growth and apoptosis in CaSki, cervical cancer cell line by arsenic compounds
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Byun JM, Jeong DH, Lee DS, Kim JR, Kim YN, Jeong EJ, Sung MS, Lee KB, Kim KT
- KMID: 2273942
- Korean J Obstet Gynecol.
- 2010 Jul;53(7):616-625.
- doi: 10.5468/kjog.2010.53.7.616
OBJECTIVE: To compare inhibition of cell growth and apoptosis in human cervical cancer cell lines (CaSki) by paclitaxel, cisplatin, arsenic trioxide and tetraarsenic oxide. METHODS: Inhibition of cell growth was determined... -
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- The Antifibrotic Effects of alpha-Tocotrienols in Primary Cultured Orbital Fibroblasts from Thyroid-Associated Ophthalmopathy Patients
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Kim SJ, Kang HK, Kang SM
- KMID: 2338050
- J Korean Ophthalmol Soc.
- 2012 Feb;53(2):323-332.
PURPOSE: To evaluate the antiproliferative and antifibrotic effects of alpha-tocotrienols in primary cultured orbital fibroblasts from thyroid-associated ophthalmopathy (TAO) patients. METHODS: Orbital fibroblasts were cultured (5 eyes from TAO patients, 5... -
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- Effectiveness of propofol pretreatment on the extent of deranged cerebral mitochondrial oxidative enzyme system after incomplete forebrain ischemia/reperfusion in rats
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Lee Y, Chung C, Oh YS
- KMID: 2157541
- J Korean Med Sci.
- 2000 Dec;15(6):627-630.
- doi: 10.3346/jkms.2000.15.6.627
It has been suggested that propofol has the protective effect on cerebral ischemia-reperfusion injury. The aim of this study is to evaluate the effect of propofol pretreatment on incomplete forebrain... -
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- Effects of Simvastatin on the Expression of VEGF in Human Retinal Pigment Epithelial Cells
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Kim KJ, Kim KS, Kim NR, Chin HS
- KMID: 2338204
- J Korean Ophthalmol Soc.
- 2012 Jun;53(6):849-855.
PURPOSE: To examine the effect of simvastatin on vascular endothelial growth factor (VEGF) expression in cultured human retinal pigment epithelial (RPE) cells under oxidative stress. METHODS: RPE cell viability was measured... -
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- The Optimal Condition of Performing MTT Assay for the Determination of Radiation Sensitivity
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Hong S, Kim IH
- KMID: 2097163
- J Korean Soc Ther Radiol Oncol.
- 2001 Jun;19(2):163-170.
PURPOSE: The measurement of radiation survival using a clonogenic assay, the established standard, can be difficult and time consuming. In this study, We have used the MTT assay, based on... -
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- Clarithromycin Susceptibility Testing of Mycobacterium avium Complex Using 2,3-Diphenyl-5-thienyl-(2)-tetrazolium Chloride Microplate Assay with Middlebrook 7H9 Broth
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Park YK, Koh WJ, Kim SO, Shin S, Kim BJ, Cho SN, Lee SM, Chang CL
- KMID: 1779172
- J Korean Med Sci.
- 2009 Jun;24(3):511-512.
- doi: 10.3346/jkms.2009.24.3.511
A series of 119 Mycobacterium avium complex isolates were subjected to clarithromycin susceptibility testing using microplates containing 2,3-diphenyl-5-thienyl-(2)-tetrazolium chloride (STC). Among 119 isolates, 114 (95.8%) were susceptible to clarithromycin and... -
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- The Effects of Adiponectin and Leptin in the Proliferation of Prostate Cancer Cells
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Lee SY, Park SJ, Jang IH, Myung SC, Kim TH
- KMID: 2311849
- Korean J Urol.
- 2009 May;50(5):493-497.
PURPOSE: With the westernization of dietary life, domestic prostate cancer prevalence has remarkably increased recently. Therefore, to examine the effects of obesity on prostate cancer, we analyzed the effects of... -
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- Troglitazone Enhances the Apoptotic Response of DLD-1 Colon Cancer Cells to Photodynamic Therapy
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Park H, Ko SH, Lee JM, Park JH, Choi YH
- KMID: 2427170
- Yonsei Med J.
- 2016 Nov;57(6):1494-1499.
- doi: 10.3349/ymj.2016.57.6.1494
PURPOSE: The aim of this study was to investigate whether the peroxisomal proliferator-activated receptor gamma (PPARγ) ligand troglitazone in combination with photodynamic therapy (PDT) enhances the apoptotic response of DLD-1... -
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- Regulation of matrix metalloproteinase-9 protein expression by 1alpha,25-(OH)2D3 during osteoclast differentiation
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Gu JH, Tong XS, Chen GH, Liu XZ, Bian JC, Yuan Y, Liu ZP
- KMID: 1737619
- J Vet Sci.
- 2014 Mar;15(1):133-140.
- doi: 10.4142/jvs.2014.15.1.133
To investigate 1alpha,25-(OH)2D3 regulation of matrix metalloproteinase-9 (MMP-9) protein expression during osteoclast formation and differentiation, receptor activator of nuclear factor kappaB ligand (RANKL) and macrophage colony-stimulating factor (M-CSF) were administered... -
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- Effect of Stimulation Intensity and Location of Cerebral Infarction on Motor Evoked Potentials in the Rat
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Chae SH, Kwon HC, Hyun JK, Kim TU, Lee YI, Lee SJ
- KMID: 2326069
- J Korean Acad Rehabil Med.
- 2010 Aug;34(4):381-386.
OBJECTIVE: To investigate the change of motor evoked potential (MEP) in the cerebral infarction, and observe the effect of stimulation intensity and location of cerebral infarction, using rat model of... -
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- The biological effects of fibrin-binding synthetic oligopeptides derived from fibronectin on osteoblast-like cells
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Kim YJ, Park YJ, Lee YM, Rhyu IC, Ku Y
- KMID: 1783646
- J Periodontal Implant Sci.
- 2012 Aug;42(4):113-118.
- doi: 10.5051/jpis.2012.42.4.113
PURPOSE: The aim of this study was to investigate the effects of synthetic fibronectin (FN) fragments, including fibrin binding sites from amino-terminal FN fragments containing type I repeats 1 to... -
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- Protective Effects of Epigallocatechin Gallate After UV Irradiation of Cultured Human Lens Epithelial Cells
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Heo J, Lee BR, Koh JW
- KMID: 1070755
- Korean J Ophthalmol.
- 2008 Sep;22(3):183-186.
- doi: 10.3341/kjo.2008.22.3.183
PURPOSE: To evaluate the protective effects of epigallocatechin gallate (EGCG) against UV irradiation of cultured human lens epithelial cells. METHODS: We irradiated cultured human lens epithelial cells with... -
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- Polyphenol (-)-epigallocatechin gallate targeting myocardial reperfusion limits infarct size and improves cardiac function
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Kim CJ, Kim JM, Lee SR, Jang YH, Kim JH, Chun KJ
- KMID: 2092273
- Korean J Anesthesiol.
- 2010 Feb;58(2):169-175.
- doi: 10.4097/kjae.2010.58.2.169
BACKGROUND: This experiment was performed to determine the effect of polyphenolic (-)-epigallocatechin (EGCG), the most abundant catechin of green tea, given at reperfusion period. METHODS: Isolated rat hearts were subjected... -
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- Naringin Protects against Rotenone-induced Apoptosis in Human Neuroblastoma SH-SY5Y Cells
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Kim HJ, Song JY, Park HJ, Park HK, Yun DH, Chung JH
- KMID: 2071682
- Korean J Physiol Pharmacol.
- 2009 Aug;13(4):281-285.
- doi: 10.4196/kjpp.2009.13.4.281
Rotenone, a mitochondrial complex I inhibitor, can induce the pathological features of Parkinson's disease (PD). In the present study, naringin, a grapefruit flavonoid, inhibited rotenone-induced cell death in human neuroblastoma... -
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- Expression of Activating Transcription Factor 3 in Ischemic Penumbra Region Following Focal Cerebral Ischemia
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Song DY, OH KM, Lee JH, Woo RS, Lee YJ, Han JT, Baik TK
- KMID: 2092940
- Korean J Anat.
- 2008 Sep;41(3):173-183.
It has been demonstrated that some of immediate early genes (IEGs) such as c-Jun or fos are induced immediately following neuronal injury and they play an important role in determining... -
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- Radiation up-regulates the expression of VEGF in a canine oral melanoma cell line
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Flickinger I, Rutgen BC, Gerner W, Calice I, Tichy A, Saalmuller A, Kleiter M
- KMID: 1705523
- J Vet Sci.
- 2013 Jun;14(2):207-214.
- doi: 10.4142/jvs.2013.14.2.207
To evaluate radiosensitivity and the effects of radiation on the expression of vascular endothelial growth factor (VEGF) and VEGF receptors in the canine oral melanoma cell line, TLM 1, cells... -
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- Toxic effects of methylmercury, arsanilic acid and danofloxacin on the differentiation of mouse embryonic stem cells into neural cells
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Kang SJ, Jeong SH, Kim EJ, Park YI, Park SW, Shin HS, Son SW, Kang HG
- KMID: 1737611
- J Vet Sci.
- 2014 Mar;15(1):61-71.
- doi: 10.4142/jvs.2014.15.1.61
This study was performed to assess the neurotoxic effects of methylmercury, arsanilic acid and danofloxacin by quantification of neural-specific proteins in vitro. Quantitation of the protein markers during 14 days... -
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- Time- dependent Changes of the Infarct Volume in a Rat Stroke Model: A Comparison of the Use of MRI and TTC- staining as Monitoring Tools
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Kwon JW, Park CK, Shin HY, Paek SH, Wang KC, Kim DG
- KMID: 1480672
- Korean J Cerebrovasc Surg.
- 2008 Sep;10(3):437-441.
OBJECTIVES: Serial changes of focal ischemic lesions as seen on magnetic resonance (MR) images and triphenyltetrazolium chloride (TTC)-stained samples of transient middle cerebral artery occlusion in a rat model were... -
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