- Turning Behavior and Substantia Nigra Structure After Unilateral Lesion and of the Rat Neostriatum
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Pae YS
- KMID: 2170815
- Ewha Med J.
- 1988 Dec;11(4):225-235.
- doi: 10.12771/emj.1988.11.4.225
After unilateral lesion of the rat neostriatum, we have been studied the relation between the behavioral chages of the rat and structural chages of the substantia nigra. We could find... -
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- Distribution of Calbindin Immunostained Neurons in the Rat Substantia Nigra
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Yoo YB
- KMID: 2283133
- Korean J Phys Anthropol.
- 2002 Sep;15(3):197-203.
It is suggested that calbindin buffers the concentration of intracellular calcium as the calcium binding protein in the cell. In the neurodegerative disease such as Parkinsonian disease, Huntington 'disease, Alzheimer... -
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- Double label immunocytochemistry for dopaminergic and parvalbuminergic neurons using diaminobenzidine and benzidine dihydrochloride in the rat substantia nigra
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Lee MY, Chung JW, Chun MH
- KMID: 1686686
- Korean J Anat.
- 1992 Dec;25(4):341-349.
No abstract available. -
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- Regional Selective Loss of Neurons in 6-Hydroxydopamine Induced Lesion in the Substantia Nigra in the Rat
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Jeon BS
- KMID: 1686394
- J Korean Neurol Assoc.
- 1992 Dec;10(4):531-538.
No abstract available. -
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- Secondary Degeneration of the Ipsilateral Thalamus and Substantia Nigra Following Cerebral Infarction in the Striatum
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Kim J, Kim J, Seo KD, Han S, Son I, Lee SI
- KMID: 2436079
- J Korean Neurol Assoc.
- 2018 Aug;36(3):203-206.
- doi: 10.17340/jkna.2018.3.13
Secondary degeneration after ischemic stroke has been demonstrated by computed tomography and magnetic resonance imaging. We report a 77-year-old man with striatal infarction followed by multifocal degeneration that developed in... -
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- Influence of Glutamate on the Circling Movement In the Unilateral Substantia Nigra-lesioned Rats
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Han MI, Chung YC, Eun HB
- KMID: 2340101
- J Korean Neuropsychiatr Assoc.
- 1997 Sep;36(5):919-926.
The aim of this study was to examine the effects of various concentrations of glutamate(10(-8), 10(-6) and 10(-4) M) on the circling movement induced by apomorphine in the unilateral substantia... -
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- Hallervorden-Spatz Disease: 2 Cases of Siblings
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Kim WS, Kim IO, Yeon KM, Song JG
- KMID: 2470395
- J Korean Radiol Soc.
- 1994 Apr;30(4):779-781.
We report two patients with Hallervorden-Spatz disease, who were diagnosed by same MR findings of marked low signal intensity in the globus and substantia nigra. They presented with ataxic and spastic gait,... -
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- A Case of Suspected Hallervorden-Spatz Disease
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Song CW, Lee SH, Lee SI, Kim DS, Park KH, Kim SW, Kim SH
- KMID: 1957414
- J Korean Neurol Assoc.
- 1992 Sep;10(3):407-412.
Hallervorden-Spatz disease is a rare, autosomal recessive disorder of mainly early childhood which is characterized by pigmentary degeneration of the globus pallidus, substantia nigra, and red nucleus. Clinically it manifests... -
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- Prospect of cell therapy for Parkinson's disease
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Pawitan JA
- KMID: 1447439
- Anat Cell Biol.
- 2011 Dec;44(4):256-264.
- doi: 10.5115/acb.2011.44.4.256
The hallmark of Parkinson's disease is on-going degeneration of dopaminergic neurons in the substantia nigra, which may be due to various etiologies. Various approaches to alleviate symptoms are available, such... -
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- A Study on the Behavioral Properties of the Rat Parkinsonian Model
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Choi HY, Kim HI, Kim JE, Bahng IS, Lee JC
- KMID: 2187639
- J Korean Neurosurg Soc.
- 1989 Feb;18(2):205-213.
Recently the reports of the autologous grafting of adrenal medullary tissue into the brain of parkinsonian patient have given the wide attention to the neurosurgeons as well as other clinicians,... -
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- Magnetic Resonance Imaging in Parkinson's Disease and Parkinsonian Syndromes
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Kim SY, Kim HJ, Yoon BW, Roh JK, Lee SB
- KMID: 2065923
- J Korean Neurol Assoc.
- 1991 Sep;9(3):332-340.
We compared heavily T2W high field MR images of 18 Parkinson's disease (PD group), 8 Parkinsonian syndromes (PS group: progressive supranuclear palsy, OPCA, Shy-Drager syndrome, atypical' parkinsonism), and 20 control... -
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- Autopy Results of Clinically Diagnosed Alzheimer's Disease
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Choi KG
- KMID: 2170880
- Ewha Med J.
- 1993 Mar;16(1):9-14.
- doi: 10.12771/emj.1993.16.1.9
Eight hundred and eighty four autopsy brains from patients with clinically diagnosed Alzheimer's disease were examined pathologically. Six hundred ninety eitht(79.96%) of the 884 cases fullfilled histological criteria for Alzheimer's... -
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- Blockade of the Subthalamo-nigral Pathway Prevents the Motor Component of Pilocarpine Induced Generalized Convulsive Seizure in Rats
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Choi JY, Kim HS, Kim YI, Park SM, Lee KS, Kim BS
- KMID: 2186048
- J Korean Neurol Assoc.
- 2000 Mar;18(2):192-198.
BACKGROUND: The substantia nigra pars reticulata is a critical site for the control of epileptic seizures. The potentiation of the inhibitory gamma-amino butyric acid (GABA) ergic input from the striatum... -
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- Genetic Basis of Parkinson Disease
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Jung KH, Jeon BS
- KMID: 2343073
- J Korean Neurol Assoc.
- 2004 Aug;22(4):281-289.
Parkinson disease (PD) is a neurodegenerative disease characterized by the selective loss of dopaminergic neurons from the substantia nigra pars compacta leading to the impairment of motor functions. Recent genetic... -
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- Experimental Demonstration of Corticostriatal Synapses in the Rat Neostriatum
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Choi SH, Lee HS, Lee HL, Kim SH
- KMID: 1965740
- Ewha Med J.
- 1988 Mar;11(1):15-23.
- doi: 10.12771/emj.1988.11.1.15
In the neostriatum of mammals the neurons and synapses discriminated into several types at the base of their morphological characteristics. A number of neurons are interneuron but some of neurons... -
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- Speech-Induced Oromandibular Dystonia
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Baik JS, Park JH, Kim JY
- KMID: 1585784
- J Korean Neurol Assoc.
- 2004 Apr;22(2):164-166.
We describe two patients with speech-induced oromandibular dystonia. One patient showed mainly jaw dystonia, while the other patient had lingual dystonia. A brain MRI revealed acute cerebral infarctions in the... -
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- Imaging of Dopaminergic System in Movement Disorders
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Kim YK, Kim SE
- KMID: 2313033
- Nucl Med Mol Imaging.
- 2007 Apr;41(2):132-140.
Parkinson's disease is a common neurodegenerative disorder that is mainly caused by dopaminergic neuron loss in the substantia nigra. Several radiopharmaceutics have been developed to evaluate the integrity of dopaminergic... -
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- Interleukin-4 Contributes to Degeneration of Dopamine Neurons in the Lipopolysaccharide-treated Substantia Nigra in vivo
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Bok E, Cho EJ, Chung ES, Shin WH, Jin BK
- KMID: 2419340
- Exp Neurobiol.
- 2018 Aug;27(4):309-319.
- doi: 10.5607/en.2018.27.4.309
The present study investigated the effects of interleukin (IL)-4 on dopamine (DA) neurons in the substantia nigra (SN) in vivo of lipopolysaccharide (LPS)-treated rat. Tyrosine hydroxylase immunohistochemistry showed a significant... -
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- Effect of Ritanserin on the Circling Movement in the Unilateral Substantia Nigra-Lesioned Rats
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Kim IH, Chung YC, Eun HB
- KMID: 1554198
- Korean J Psychopharmacol.
- 1999 Oct;10(2):130-137.
OBJECTIVE: Recently, the serotonin-dopamine interaction is being regarded as a possible mechanism for both less extrapyramidal symptoms and good therapeutic effect on negative symptoms which are outstanding advantages of atypical... -
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- Brain MRI Findings of the Olivopontocerebellar Atrophy
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Park KH, Park DW, Oh JC, Lee YJ, Lee SR, Hahm CK
- KMID: 2103435
- J Korean Radiol Soc.
- 1999 Oct;41(4):629-634.
- doi: 10.3348/jkrs.1999.41.4.629
PURPOSE: To demonstrate the MRI findings of olivopontocerebellar atrophy. MATERIALS AND METHODS: We retrospectively reviewed the MRI findings of eight patients who had been diagnosed by clinical manifestation and the... -
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