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Sirolimus-induced pneumonitis in a renal transplant recipient

Kim JS, Shin AY, Kim JH, Kim EH, Oak JH, Yang CW

  • KMID: 2259349
  • Korean J Med.
  • 2010 Oct;79(4):438-442.
Sirolimus is a promising immunosuppressive agent with low nephrotoxicity and anti-tumor effects; it replaces calcineurin inhibitors, but serious adverse effects have been reported. We report on sirolimus-induced pneumonitis, which is...
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Very Late Stent Thrombosis Related to Fracture of a Sirolimus-Eluting Stent

Nam CW, Kim KB, Chung IS

Although late stent thrombosis is a very rare complication after a drug-eluting stent implantation, this could induce significant sequelae. Several mechanisms for very late stent thrombosis have been suggested. We...
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Therapeutic Drug Monitoring of Tacrolimus and Sirolimus

Chun S, Lee W, Min WK

  • KMID: 2040473
  • J Lab Med Qual Assur.
  • 2008 Dec;30(2):241-242.
No abstract available.
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A Case of Interstitial Pneumonitis Associated with Sirolimus Treatment in Renal Transplantation Recipient

Lee JY, Kim SY, Byun SW, Yeo YS, Chang JW, Yang WS, Kim SB, Park JS, Park SK

  • KMID: 1477254
  • Korean J Nephrol.
  • 2008 Sep;27(5):611-615.
Sirolimus is a promising immunosuppressive drug for renal transplantation to avoid nephrotoxicity of calcineurin inhibitor. However, it has been associated with uncommon but, important pulmonary toxicity. We present a case...
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A Case of Coronary Artery Aneurysm after Sirolimus-Eluting Stent Implantation

Park KS, Cha ST, Sung JH, Kim IJ, Lim SW, Cha DH

This report describes the case of a 26-year-old male diagnosed with angina on exertion. A diagnostic coronary angiography revealed significant luminal narrowing at the middle third of the left anterior...
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Sirolimus therapy for fetal cardiac rhabdomyoma in a pregnant woman with tuberous sclerosis

Park H, Chang CS, Choi SJ, Oh SY, Roh CR

Rhabdomyoma is the most common fetal cardiac tumor, and its development is related to tuberous sclerosis. Fetal cardiac rhabdomyomas often spontaneously regress in utero or after birth, but large tumors...
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Verruca Eradication Following Conversion to Sirolimus in a Renal Transplant Recipient after Longstanding Cyclosporine A Treatment

Joo DJ, Kim SH, Huh KH, Kim YS

We present the case of a 50-year-old male kidney transplant recipient whose verruca skin warts completely disappeared after conversion of immunosuppressive treatment from cyclosporine A to sirolimus. Before conversion, the...
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A Case of Squamous Cell Carcinoma in Nasal Cavity Treated with Conversion to Sirolimus in a Patient with Kidney Transplantation

Ryu TH, Choi SH, Jung P, Lee KH, Kim HS, Oh JS, Kim SM, Sin YH, Kim JK

Conversion of immunosuppressants to sirolimus, an inhibitor of mammalian target of rapamycin, is a useful treatment option for prevention of the adverse events of immunosuppressants such as calcineurin inhibitor in...
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The Changes of Slit Diaphragm Molecules After Using Sirolimus

Choi JY, Han GD, Kim YJ, Park YH

  • KMID: 2196735
  • J Korean Soc Pediatr Nephrol.
  • 2010 Oct;14(2):143-153.
PURPOSE: Recently, massive proteinuria has been observed in some transplant patients after switching cyclosporine A (CsA) to sirolimus. To evaluate the pathogenesis of sirolimus-associated proteinuria, we investigated the early changes...
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Sirolimus Combination with Tacrolimus in Kidney Transplant Recipients at High Immunological Risk: Observational Results 3 Years after Transplantation

Lee J, Song SH, Lee JG, Kim BS, Huh KH, Kim YS

BACKGROUND: The optimal immunosuppressive strategy for renal transplant recipients at high immunological risk requires clarification. We compared the 3 year outcomes of a sirolimus group (tacrolimus plus sirolimus) to those...
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Using Sirolimus for Posttransplant Management and Reduction of Tuberous Sclerosis Complex Progression in a Patient with End Stage Renal Disease Caused by Tuberous Sclerosis Complex

Lee KH, Kim HS, Yun SH, Lee JH, Oh JS, Kim SM, Sin YH, Kim JK

Tuberous sclerosis complex (TSC) is a neurocutaneous disease characterized by the formation of hamartomas in multiple organs. TSC can show lesions including facial angiofibroma, shagreen patch on the skin, cortical...
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Migration of a sirolimus-eluting stent from the ostium of the left main coronary artery to the right deep femoral artery

Won KB, Kim BK, Ko YG, Hong MK, Jang Y, Shim WH

No abstract available.
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Proliferation Signal Inhibitors: Sirolimus and Everolimus

Kim JK

  • KMID: 2201822
  • J Korean Soc Transplant.
  • 2006 Dec;20(2):143-148.
Proliferation signal inhibitors are a new class of immunosuppressant. They inhibit the mammalian target of rapamycin and blocks the cell cycle of various cell types, including T and B lymphocytes....
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A Case of Huge Coronary Aneurysm After Implantation of a Sirolimus-Eluting Stent

Seo KW, Tahk SJ, Choi SY, Yoon MH, Choi BJ, Lim HS, Shin JH, Hwang GS, Kang SJ, Kim JW, Lim NK, Lee MH

This report describes the case of a 62-year-old woman who was previously diagnosed with stable angina. Coronary angiography revealed clinically significant stenosis in the middle of the left anterior descending...
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A Case of Facial Angiofibromas in Tuberous Sclerosis Treated with Combination of 10,600 nm Carbon Dioxide Fractional Laser, Pin-hole Carbon Dioxide Laser, Vascular Laser and Topical Rapamycin

Kim MJ, Roh NK, Lee YW, Choe YB, Ahn KJ

  • KMID: 2129429
  • Korean J Dermatol.
  • 2015 Nov;53(9):743-745.
No abstract available.
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Successful Sirolimus Treatment of Multiple Visceral Kaposi's Sarcoma in a Renal Allograft Patient

Kim MH, Kim MS, Cha YJ, Park KS, Kim BS, Lee S

The use of immunosuppressant's increases the risk of developing malignancies in renal allograft patients. One of the most important malignancies, Kaposi's sarcoma, can cause mortality and graft failure among renal...
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A Case of Kaposi's Sarcoma Improved by Sirolimus Treatment in the Kidney Transplant Recipient

Lee SM, Park SY, Kim SJ, Song YS, Song HH, Lee S, Nam ES, Oh J

  • KMID: 2253213
  • Korean J Nephrol.
  • 2009 Jan;28(1):82-87.
The incidence of Kaposi's sarcoma (KS) increases in kidney transplant recipients who had the immunosuppressive therapy. The usual treatment of KS is to reduce the dosage of immunosuppressive agents, with...
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Sirolimus/steroids Maintenance Therapy after Early Cyclosporine Withdrawal: 12-month Efficacy and Safety Results of Multicenter Single Arm Pilot Study in Primary Renal Allograft Recipients in Korea

Ju MK, Han DJ, Kim SJ, Moon IS, Kim YL, Kim HC, Kim SJ, Kim SJ, Kim SI, Kim YH, Oh CK, Kim YS

PURPOSE: Sirolimus has potent anti-rejection activity as well as the ability to prolong allograft survival and reduce nephrotoxicity. This study was designed to evaluate the efficacy and safety of sirolimus...
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Chylous Manifestations and Management of Gorham-Stout Syndrome

Cho S, Kang SR, Lee BH, Choi S

Gorham-Stout disease (GSD) was first described by Gorham and colleagues in 1954, but its precise mechanism and cause remain to be elucidated. In this condition, voluminous and potentially fatal chylous...
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A Case of Late Recurrent Vasospasm After Sirolimus-Eluting Stent Implantation

Lee TK, Lee HC, Hwang KW, Chun KJ, Hong TJ, Shin YW

A 67-year-old male with stable angina was admitted to our cardiovascular center. He had neither any history of smoking, diabetes mellitus, hypertension, cerebrovascular accident nor family history of coronary artery...
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