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Rhinovirus-Induced Mucin Gene Expression in Airway Epithelial Cells

Jang YJ, Kwon HJ, Wang JW, Lee BJ, Chung YS

BACKGROUND AND OBJECTIVES: It is unclear whether rhinovirus infections promote mucus secretion in airway epithelial cells. Increase of mucin gene expression and mucin production is associated with mucus hypersecretion. We...
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Effect of Clarithromycin on Rhinovirus-16 Infection in A549 Cells

Jeon HK, Kwon HJ, Nam SY, Lee BJ, Jang YJ

  • KMID: 2297693
  • J Rhinol.
  • 2005 May;12(1):39-45.
BACKGROUND AND OBJECTIVES: Rhinovirus enters into airway epithelial cells via the membrane bound receptor ICAM-1. Infected epithelial cells secrete the cytokines such as IL-6 and IL-8, which induce neutrophil migration...
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New Tread of Association of Rhinovirus and Asthma

Kim WK

  • KMID: 2314885
  • Pediatr Allergy Respir Dis.
  • 2008 Sep;18(3):202-207.
Exacerbations of asthma is major causes of morbidity, mortality, and health-care costs. Over the decade, studies using new molecular diagnostic techniques have established that respiratory viruses are a major cause...
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Pathophysiology and Treatment of Common Cold due to Rhinovirus Infection

Jang YJ

  • KMID: 2275991
  • Korean J Otolaryngol-Head Neck Surg.
  • 2003 Feb;46(2):93-99.
No abstract available.
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The Effect of Histamine on Rhinovirus-16 Infection in Airway Epithelial Cells

Jang YJ, Lee SH, Kwon HJ, Lee BJ, Chung YS

  • KMID: 2276571
  • Korean J Otolaryngol-Head Neck Surg.
  • 2006 Feb;49(2):182-186.
BACKGROUND AND OBJECTIVES: It is not known if allergies promote rhinovirus infections or aggravate the symptoms of common cold due to rhinoviruses. Histamine is an important immune mediator that induces...
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Increase of Rhinovirus Replication in Airway Epithelial Cells by Staphylococcal Enterotoxin A and B

Jang YJ, Wang JH, Kwon HJ, Chung YS, Lee BJ

  • KMID: 1881277
  • Korean J Otolaryngol-Head Neck Surg.
  • 2006 Nov;49(11):1071-1076.
BACKGROUND AND OBJECTIVES : The toxins generated from Staphylococcus aureus, Staphylococcal enterotoxin A (SEA) and B (SEB), are reported to have an important role in the pathogenesis of chronic rhinosinusitis....
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Detection of Rhinovirus from Children with Lower Respiratory Tract Infections by Reverse Transcription Polymerase Chain Reaction

Kwak YH, Choi EH, Lee HJ

  • KMID: 1515428
  • Infect Chemother.
  • 2003 Feb;35(1):1-11.
BACKGROUND: Rhinovirus has long been considered as the most important cause of uncomplicated upper respiratory infection and a trigger of asthma exacerbation, and was recently been widely appreciated for it's...
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Rhinovirus Associated Severe Respiratory Failure in Immunocompetent Adult Patient

Kim K, Song YH, Park JH, Park HK, Kim SY, Jung H, Lee SS, Koo HK

Rhinovirus infection is typically associated with the common cold and has rarely been reported as a cause of severe pneumonia in immunocompetent adults. A 55-year-old previous healthy woman, who consumed...
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Rhinovirus Infection Study Model Using Organ Culture of Turbinate Mucosa

Kim SH, Kwon HJ, Chung YS, Lee BJ, Jang YJ

  • KMID: 2074509
  • Korean J Otolaryngol-Head Neck Surg.
  • 2004 Jul;47(7):632-638.
BACKGROUND AND OBJECTIVES: To have better understanding on the pathophysiology of rhinovirus infection, an availability of an ideal experimental model is of utmost importance. We aimed to develop a new...
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Rhinovirus stimulation of anti-inflammatory cytokines in human bronchial epithelial cells

Kim YC, Lee JH, Kim MO, Kim TH, Sohn JW, Yoon HJ, Shin DH, Park SS

  • KMID: 2081175
  • Korean J Med.
  • 2005 Dec;69(6):668-675.
BACKGROUND: Rhinovirus is an important precipitating factor in acute exacerbation of asthma and COPD. Rhinovirus has short incubation period, causing transient inflammatory process and then has spontaneous resolution. We hypothesized...
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Fatal and Near-fatal Cases of Lower Respiratory Tract Infection with Human Rhinovirus Group A

Yoon JR, Choi J, Callaway Z, Kim HB, Kim CK

  • KMID: 2315018
  • Pediatr Allergy Respir Dis.
  • 2010 Mar;20(1):76-80.
Human rhinoviruses (HRV) mostly cause mild and self-limiting upper respiratory tract infections. We report 2 infants with acute respiratory failure requiring mechanical ventilation, 1 of whom deteriorated to death. The...
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Effect of Rhinovirus-16 Infection on the Electrophysiological Property of Cultured Tracheal Epithelial Cells

Jang YJ, Widdicombe JH

  • KMID: 1923106
  • Korean J Otolaryngol-Head Neck Surg.
  • 2003 Mar;46(3):211-215.
BACKGROUND AND OBJECTIVES: Rhinovirus infection on the airway epithelial cells results in derangement in mucociliary clearance. However, the contribution of altered ion transport across the epithelial cells in rhinovirus-induced alteration...
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Rhinovirus and childhood asthma: an update

Song DJ

Asthma is recognized as a complex disease resulting from interactions between multiple genetic and environmental factors. Accumulating evidence suggests that respiratory viral infections in early life constitute a major environmental...
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Comparison of Rhinovirus Infection Rate and Virus-induced Cytokine Secretion between Nasal Polyp Mucosae and Normal Sphenoid Sinus Mucosae Organ Culture Model

Wang JH, Kwon HJ, Chung YS, Lee BJ, Jang YJ

  • KMID: 2131885
  • J Rhinol.
  • 2006 Nov;13(2):115-119.
BACKGROUND AND OBJECTIVES: Human rhinovirus (HRV) infection is the primary cause of the common cold. It was often reported that the frequency of viral rhinitis is higher among patients with...
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Updates in the Relationship Between Human Rhinovirus and Asthma

Kim WK, Gern JE

Human rhinovirus (HRV) is a nonenveloped, single stranded RNA virus belonging to the family Picornaviridae. HRV infections can cause both upper and lower respiratory illnesses in children and adults. Lower...
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Virus-associated Rhabdomyolysis in Children

You J, Lee J, Park YS, Lee JH

PURPOSE: Virus-associated rhabdomyolysis is very rare. We report 15 patients with rhabdomyolysis caused by various viruses. METHODS: Fifteen patients who were diagnosed with rhabdomyolysis and a viral infection were included in...
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Effect of propofol and etomidate in respiratory epithelial cell infected with rhinovirus

Lee YK, Son HJ, Ku SW, Jang YJ, Lee HJ, Kim JU

BACKGROUND: There have been no previous studies on the effect of anesthetic agents on rhinovirus (RV) infection, which is the most common pathogen of the common cold in human airway...
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Evaluation of Seeplex(TM) RV Detection Kit for Detecting Rhinovirus, Human Metapneumovirus, and Coronavirus

Sung H, Park SJ, Woo YD, Choi BH, Kim MN

BACKGROUND: Direct antigen test (DAT) and culture are primary tests to diagnose infections by respiratory viruses, but are mainly available for the traditional viral pathogens such as respiratory syncytial...
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The Role of Respiratory Viral Infections in Exacerbation of Asthma and Chronic Obstructive Pulmonary Disease (COPD)

Yoo JY, Kim DG, Eom KS, Shin T, Park YB, Lee JY, Jang SH, Bahn JW, Kim CH, Park SM, Lee MG, Hyun IG, Lee KM, Jung KS

  • KMID: 2318692
  • Tuberc Respir Dis.
  • 2005 Nov;59(5):497-503.
BACKGROUNDS: The exacerbations of asthma and chronic obstructive pulmonary disease (COPD) have been suggested to be associated with respiratory tract viral infections (RTVIs). However, the rates of virus detection in...
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Prevalence of respiratory viral infection in children hospitalized for acute lower respiratory tract diseases, and association of rhinovirus and influenza virus with asthma exacerbations

Kwon JM, Shim JW, Kim DS, Jung HL, Park MS, Shim JY

PURPOSE: In this study, we aimed to investigate the prevalence of year-round respiratory viral infection in children with lower respiratory tract infection (LRTI) and the relationship between respiratory viral infection...
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