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Correlation of c-erbB-2 protein overexpression in human breast carcinoma with nodal status, tumor size, stage, age and survival

Kim BS, Noh DY, Choe KJ, Lee KK, Park SH, Kim YI, Park JB

  • KMID: 1694059
  • J Korean Cancer Assoc.
  • 1991 Mar;23(1):20-28.
No abstract available.
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Significance of EGFR and c-erbB-2 Expression in Extrahepatic Bile Duct Cancer

Son GS, Choi SY, Suh SO, Kim YC

  • KMID: 1928539
  • Korean J Hepatobiliary Pancreat Surg.
  • 1998 Feb;2(1):95-102.
Until now, surgical treatment of bile duct carcinoma has been unsatisfactory. There have been few reports dealing with the clinical significance of epidermal growth factor receptor(EGFR) and c-erbB-2 in bile...
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Overexpression of hTERT and c-erbB-2 are correlated in ovarian epithelial cancer

Kang S, Park NH, Lee YK, Kim JW, Song YS, Kang SB, Lee HP

  • KMID: 2244587
  • Korean J Gynecol Oncol.
  • 2006 Jun;17(2):142-146.
OBJECTIVE: It is still unclear how the abnormal hTERT expression is involved in the process of ovarian carcinogenesis. A recent report demonstrated that the introduction of c-erbB-2 could efficiently induce...
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The mechanism of c-erbB-2 gene product increase in stomach cancer cell lines

Bae CD, Park SE, Seong YS, Kim SW, park JB, Park JG

c-erbB-2 oncogene encodes a growth factor receptor whose amino acid sequence has extensive homology with human epidermal growth factor receptor. It is frequently overexpressed in human breast, ovary, lung, and...
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Detection of C-erbB-2 Internal Domain in Bladder Tumor

Kim WJ, Lee HM, Song HG

  • KMID: 2060528
  • Korean J Urol.
  • 1994 Oct;35(10):1041-1046.
c-erbB-2 overexpression appears to play a role in determining the malignant potential of some human cancers. Using a specific monoclonal antibody to c-erbB-2 internal domain, 25 transitional cell carcinoma and...
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Immunohistochemical Expression of c-erbB-2 Protein in Breast Cancer

Kim BN, Park HY, Lee YH, Park JY, Son YK

  • KMID: 2209461
  • J Korean Surg Soc.
  • 2002 Jun;62(6):456-462.
PURPOSE: A clinical trial that evaluated the efficacy of Herceptin(R) (anti-erbB2 antibody) as a first-line therapy for metastatic breast cancer was presented. It was demonstrated that 38% of the metastatic...
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The Expression of p53, c-erbB-2 and nm23 Proteins in Breast Cancer

Lee KY, Kim YG, Kim YS, Han KJ, Kang CS, Kim JA, Kim WI, Shim SI

  • KMID: 1921777
  • Korean J Pathol.
  • 1999 Feb;33(2):88-95.
Recently, p53, c-erbB-2 and nm23 proteins have been studied in breast cancer. The expression of p53 protein indicates the mutation of p53 gene known as a tumor supressor gene, and...
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Sebaceous carcinoma of the eyelids: frequent expression of c-erbB-2 oncoprotein

Cho KJ, Khang SK, Koh JS, Chung JH, Lee SS

Ocular sebaceous carcinoma (OSC) is an uncommon malignancy with a potential to recur and metastasize. Some characteristics of sebaceous carcinoma, such as female preponderance, shown in the present series during...
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Epidermal Growth Factor Receptor and c-erbB-2 Expressions in Biliary Tract Cancers

Kim JS, Ahn WS, Kim KH, Choi CS, Yoon HK, Choi YK

  • KMID: 1866372
  • Korean J Hepatobiliary Pancreat Surg.
  • 2006 Dec;10(4):13-18.
PURPOSE: The expressions of epidermal growth factor receptor (EGFR) and c-erbB-2 have been considered to be implicated in the genesis and progression of cholangiocarcinomas. However, their clinical roles and pathological...
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C-erbB-2 Protein Expression and Correlation in Sera and Tumors of Non-Small Cell Lung Cancer Patients

Ryoo HM, Lee SY, Lee KH, Hyun MS, Kim MJ

  • KMID: 2329196
  • J Korean Cancer Assoc.
  • 2000 Dec;32(6):1100-1108.
PURPOSE: We have examined the expression of c-erbB-2 oncogene in sera and tissues of non-small cell lung cancer patients. MATERIALS AND METHODS: Serum levels of c-erbB-2 protein were measured by an...
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Immunohistochemical detection of p53 protein, c-erbB-2 protein, epidermal growth factor receptor protein and proliferating cell nuclear antigen in gastric carcinoma

Jang WI, Yang WI, Lee CI, Kim HS, Song KS, Cho MY, Park JK, Shim YH

There is increasing evidence that genes involved in normal cell growth and differentiation (oncogenes) or genes that encode for growth factors are important in determining the development and biologic aggressiveness...
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Fascin-1 Protein Expression in Gastric Carcinoma

Chae SW, Sohn JH

  • KMID: 2277680
  • Korean J Pathol.
  • 2006 Apr;40(2):112-117.
BACKGROUND: Fascin-1 is a globular cross-linking and actin bundling protein that provides mechanical support to cellular protrusions and cell motility. The expression of fascin in epithelial neoplasms has been recently...
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Expression of c-erbB-2 and Cyclooxygenase-2 in Pancreatic Ductal Adenocarcinoma

Choi HJ, Kim HJ, Yun SS, Choi JH

  • KMID: 1521666
  • Korean J Pathol.
  • 2007 Jun;41(3):171-175.
Background : Carcinoma of the pancreas is a fatal malignant disease with limited therapeutic options. Cyclooxygenase-2 (COX-2) and c-erbB-2 are known to be involved in the carcinogenesis, differentiation and invasiveness...
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Prognostic Significance of Immunohistochemical Expression of EGFR and C-erbB-2 Oncoprotein in Curatively Resected Gastric Cancer

Song HS, Do YR, Kim IH, Sohn SS, Kwon KY

  • KMID: 2166138
  • Cancer Res Treat.
  • 2004 Aug;36(4):240-245.
PURPOSE: The purpose of this study was to investigate the prognostic significance of the expression of EGFR and C-erbB-2 gene products by immunohistochemical analysis for curatively resected gastric adenocarcinoma. MATERIALS...
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Human Epidermal Growth Factor Receptor 2-positive Mucinous Carcinoma with Signet Ring Cell Differentiation, Which Showed Complete Response after Neoadjuvant Chemotherapy

Jang Y, Cho EY, Cho SY

Mucinous carcinoma (MC) is a rare subtype of breast cancer, which is composed of tumor cells floating in the abundant extracellular mucin. This form of cancer is usually estrogen receptor/progesterone...
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Expression of c-erbB2 and p53 in Curatively Resected Gastric Cancer: Correlation with Clinicopathologic Features and Prognosis

Hur H, Yi JM, Lee IK, Song KY, Kim W, Park CH, Jeon HM

PURPOSE: We investigated the correlation between expression of c-erbB-2 and p53 proteins and clinicopathologic features of gastric cancer to reveal prognostic factors. METHODS: 125 patient records under going curative resection for...
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Expression of c-erbB-2 Oncoprotein and DNA Topoisomerase II-alpha in Premalignant Lesions and Invasive Squamous Cell Carcinomas of the Uterine Cervix

Shin SH, Koo HM, Kim JS, Mun HK, Lee JD, Kim SY, Han JH, Cho TI, Lee TJ

  • KMID: 2270617
  • Korean J Obstet Gynecol.
  • 2002 Dec;45(12):2124-2129.
OBJECTIVE: The relationship was studied between expression of c-erbB-2 oncoprotein and topoisomerase II-alpha as proliferating marker in precancerous lesions and invasive squamous carcinomas of the uterine cervix. METHODS: Total 81 formalin-fixed,...
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Clinicopathologic Significance of p53 and c-erbB-2 Protein Expression in Breast Carcinoma

Kim JK, Song YJ, Cho SI, Ryu DH, Yun HY, Sung RH

PURPOSE: Reliable prognostic factors, including clinicopathological parameters (Ed-alternatively, "Reliable clinicopathologic prognostic factors") such as tumor size, axillary lymph node involvement, histologic grade, menopausal patient status and steroid receptor status, are...
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Clinicopathologic Significance of p53 and c-erbB-2 Protein Expression in Breast Carcinoma

Kim JK, Song YJ, Cho SI, Ryu DH, Yun HY, Sung RH

  • KMID: 2209431
  • J Korean Surg Soc.
  • 2002 Apr;62(4):282-287.
PURPOSE: Reliable prognostic factors, including clinicopathological parameters (Ed-alternatively, "Reliable clinicopathologic prognostic factors") such as tumor size, axillary lymph node involvement, histologic grade, menopausal patient status and steroid receptor status, are...
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Type of Intestinal Metaplasia in the Surrounding Mucosa of Gastric Carcinoma and Expression of bcl-2, p53 and c-erbB-2 Prtein in Gastric Carcinoma

Cho SC, Kwon KY

  • KMID: 2059286
  • J Korean Cancer Assoc.
  • 1999 Oct;31(5):898-911.
PURPOSE: This study was carried out to clarify significance of types of intestinal metaplasia and roles of bcl-2, p53 and c-erbB-2 protein in the development of gastric carcinoma. MATERIALS AND METHODS:...
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