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The carcinogenic effect with the instillation of N-methyl-N-nitro-N-nitrosoaguanidine in Sprague-Dawley rats in the colon and rectum

Lee BH, Kim HD, Kim HM, Kim SH, Suh JI, Woo ZH

  • KMID: 1686438
  • J Korean Soc Coloproctol.
  • 1992 Apr;8(1):1-8.
No abstract available.
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Effect of Pinealectomy on the Renin-Angiotensin System in Sprague-Dawley Rats

Moon YC, Baek WS, Kim JM

  • KMID: 2339517
  • J Korean Neurosurg Soc.
  • 1986 Dec;15(4):779-786.
Experiments were performed to investigate the effects of pinealectomy on the renin-angiotensin system in Sprague-Dawley rats. The results obtained were as follows. 1) There was no differences of systolic blood...
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An experimental study on the mandibular growth by the partial glossectomy of the rats

Hyun SH, Kim KW

  • KMID: 2400522
  • Korean J Orthod.
  • 1995 Oct;25(5):567-575.
The purpose of this study was to investigate the effect of the partial glossectomy on the mandibular growth of growing rats. Thirty one Sprague-Dawley rats four weeks old were divided...
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The Effect of Experimental Varicocele on Fertility in Adolescent Rats

Ha TJ, Choi H

  • KMID: 2060244
  • Korean J Urol.
  • 1990 Apr;31(2):183-189.
Varicocele is considered as one of common etiology for subfertility in men and recently it is acknowledged that varicocele first developed in puberty exert more severe damage to testicular structure...
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Melatonin enhances hepatic glutathione-peroxidase activity in Sprague-Dawley rats

Kim CY, Yun CS, Park DH, Choi WS, Kim JS

  • KMID: 1554558
  • Korean J Physiol Pharmacol.
  • 1997 Apr;1(2):221-224.
Effects of melatonin on hepatic glutathione-peroxidase (GSH-Px) and glutathione-reductase (GSH-reductase) activities were studied in Sprague-Dawley (SD) rats administered i.p. (10 mg/kg body weight) with melatonin during 15 days. The activity of cytosolic GSH-reductase...
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Genetic heterogeneity of Pneumocystis carinii from rats of several regions and strains

Chung BS, Pars YK, Huh S, Yu JR, Kim J, Shi X, Cho SR, Lee SH, Hong ST

Pneumocystis carinii is a major opportunistic pathogen which has been found in the lungs of a wide variety of mammalian host species, and the fact suggests the possibility of intraspecific...
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Airway Inflammation and Responses in the Bronchial Asthma Model in Sprague-Dawley Rats Sensitized by Ovalbumin

Na MJ, Lee BH, An CH, Kim JY, Park IW, Choi BW, Hue SH

  • KMID: 2318272
  • Tuberc Respir Dis.
  • 2000 Jan;48(1):33-44.
BACKGROUND: To evaluate airway responses and inflammation to antigen in Sprague-Dawley rat asthma model, we examined airway responses, serial histologic changes of the lung, and the relationship between airway responses...
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Longevity of Antibodies to Live Orientia tsutsugamushi Inoculated in Sprague Dawley Rats

An CN, Kim S, Park SY, Kim TY, Baek LJ, Kim CJ, Shin KS

  • KMID: 1551981
  • J Korean Soc Virol.
  • 1998 Jun;28(2):193-201.
In Sprague Dawley (SD) rats, antibodies against strains of Orinentia tsutsugamushi, Kato, Karp and Gilliam, were produced in order to investigate their longevity and cross-reactivities to their corresponding homologous and...
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THE EffECT OF THE 5-FLUOROURACIL ON THE HAIR OF RAT: SCANNING ELECTRONMICROSCOPIC STUDY

Choi YC, Kim KW, Lee JH

  • KMID: 1960887
  • J Korean Assoc Maxillofac Plast Reconstr Surg.
  • 1998 May;20(2):158-165.
This study was undertaken to observe the effects of the antineoplastic agent, 5-Fluorouracil(5 FU) on the hair in Sprague-Dawley white rats. Twenty four sprague-Dawley strain white rats, each weighing about...
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Testicular Development and the Formation of Spermatic Granulomas after Experimental Ligation of The Vas Deferens in Immature Rats

Kang HJ, Woo JW, Lee CK, Choi S, Rhew HY

  • KMID: 2327932
  • J Korean Androl Soc.
  • 1996 Dec;14(2):71-80.
The aims of this study were to analyse the results of proximal edn ligation of male reproductive tract of Sprague-Dawley rats prior to maturation and to observe the different...
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Chemical Orchiectomy Using Absolute Alcohol Injection into Rat Testicles

Yoon KJ, Yoon YR

  • KMID: 2289983
  • Korean J Urol.
  • 1998 Sep;39(9):858-862.
PURPOSE: In patients suffering from prostate cancer, endocrine treatment is commonly applied to either locally advanced or metastatic prostate cancer. But, there are many side effects with endocrine treatment in...
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Carboxyhemoglobin Dissociation Pattern by Age in the Rat

Kim SM, Kim H, Cho SH

  • KMID: 1983269
  • Korean J Prev Med.
  • 1991 Dec;24(4):507-515.
One, two, six and ten week old Sprague-Dawley rats were exposed to carbon monoxide at 3,700 ppm for 30 minutes, and carboxyhemoglobin was measured immediateley, 5, 30, 60, 90, 120...
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Application and Limitations of Awake Cystometry in Sprague-Dawley Rats with Partial Bladder Outlet Obstruction as a Model of Overactive Bladder or Obstruction

Park SH, Jin LH, Kwon YH, Yoon SM, Ryu JK, Lee T

  • KMID: 2311848
  • Korean J Urol.
  • 2009 May;50(5):486-492.
PURPOSE: Partial bladder outlet obstruction (PBOO) in rats leads to changes in bladder function, such as obstruction and detrusor overactivity (DO). The aim of our study was to observe factors...
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The effect of both oophorectomy on serotonin level in cerebral cortex and hippocampus of the female Sprague-Dawley rat

Ko EM, Jeon HA, Park MC

  • KMID: 2262110
  • Korean J Obstet Gynecol.
  • 2000 Nov;43(11):1926-1931.
OBJECTIVE: The purpose of this study is to investigate the effect of chronic deprivation of estradiol on the serotonin level in Sprague-Dawley rat's cerebral cortex and hippocampus. METHODS: One hundred...
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Proliferation of Cultured Vascular Smooth Muscle Cells(VSMCs) Obtained from Aortas of Insulin Dependent Diabetic Rats

Yoo HJ

  • KMID: 1535754
  • J Korean Geriatr Soc.
  • 1997 Oct;1(1):48-54.
BACKGROUND: Vascular smooth muscle cells(VS-MCs) from diabetic animals proliferate more than that from non-diabetic ones. The proliferative ability of cultured VSMCs is changed by the kind of experimental animals, experimental...
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The Effect of Halothane, Enflurane and Isoflurans on Hepatic Function in Acute Hypoxic Rats

Lee GY

The effects of halothane, enflurane and isoflurane on hepatic function in 50 Sprague-Dawley rats in the presence of acute mild hypoxic(oxygen 14%) condition were compared. Anesthetics were administered in 1...
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The Effects of Experimental Cryptorchidism and Subsequent Orchiopexy on the Fertility and Histologic Changes

Chung KH, Choi H

  • KMID: 2036913
  • Korean J Urol.
  • 1988 Jun;29(3):367-374.
Cryptorchidism is one of the most common anomalies of genitourinary tract in childhood but its pathogenesis has not been determined. And because the long term efficacy of treatment for cryptorchidism...
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Increase in rat plasma antioxidant activity after E. coli lipopolysaccharide administration

Lee KY, Perretta S, Zar H, Mueller RA, Boysen PG

It is well recognized that the sensitivity of animals to lipopolysaccharide (LPS) endotoxin varies tremendously. And, it has been recently observed that Sprague-Dawley rats dramatically increase the...
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Reference Data of the Main Physiological Parameters in Control Sprague-Dawley Rats from Pre-clinical Toxicity Studies

Han ZZ, Xu HD, Kim KH, Ahn TH, Bae JS, Lee JY, Gil KH, Lee JY, Woo SJ, Yoo HJ, Lee HK, Kim KH, Park CK, Zhang HS, Song SW

  • KMID: 2312061
  • Lab Anim Res.
  • 2010 Jun;26(2):153-164.
The purpose of this paper is to provide reference data related to the body weight, food & water consumptions, urinalysis, hematology and serum biochemistry parameters and absolute & relative organ...
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The Expression of NADPH-diaphorase in Corneal Neovascularization of streptozotocin Induced Diabetic Rat

Park BW, Hong JW

  • KMID: 2336818
  • J Korean Ophthalmol Soc.
  • 1999 Apr;40(4):908-914.
We evaluated the effect of nitric oxide on the corneal neovascularization in diabetic rats. The NADPH-diaphorase histochemistry was used to investigate the relationship between the nitric oxide synthase activity and...
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