- Bioinformatics Approaches for the Identification and Annotation of RNA Editing Sites
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Lee SY, Kim JH
- KMID: 2055575
- J Genet Med.
- 2013 Jun;10(1):27-32.
- doi: 10.5734/JGM.2013.10.1.27
Post-transcriptional nucleotide sequence modification of transcripts by RNA editing is an important molecular mechanism in the regulation of protein function and is associated with a variety of human disease phenotypes.... -
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- Identification of Diverse Adenosine-to-Inosine RNA Editing Subtypes in Colorectal Cancer
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Lee SH, Kim HP, Kang JK, Song SH, Han SW, Kim TY
- KMID: 2394826
- Cancer Res Treat.
- 2017 Oct;49(4):1077-1087.
- doi: 10.4143/crt.2016.301
PURPOSE: RNA editing generates protein diversity by altering RNA sequences in coding regions without changing the overall DNA sequence. Adenosine-to-inosine (A-to-I) RNA editing events have recently been reported in some... -
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- Curcumin modulates the apolipoprotein B mRNA editing by coordinating the expression of cytidine deamination to uridine editosome components in primary mouse hepatocytes
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He P, Tian N
- KMID: 2443606
- Korean J Physiol Pharmacol.
- 2019 May;23(3):181-189.
- doi: 10.4196/kjpp.2019.23.3.181
Curcumin, an active ingredient of Curcuma longa L., can reduce the concentration of low-density lipoproteins in plasma, in different ways. We had first reported that curcumin exhibits hypocholesterolemic properties by... -
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- Identification of neoantigens derived from alternative splicing and RNA modification
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Park J, Chung YJ
- KMID: 2462037
- Genomics Inform.
- 2019 Sep;17(3):e23.
- doi: 10.5808/GI.2019.17.3.e23
The acquisition of somatic mutations is the most common event in cancer. Neoantigens expressed from genes with mutations acquired during carcinogenesis can be tumor-specific. Since the immune system recognizes tumor-specific... -
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- mRNA Expression and RNA Editing (2451 C-to-U) of IL-12 Receptor beta2 in Adult Atopic Patients
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Kim EJ, Lee WM, Ha JS, Ryoo NH, Jeon DS, Kim JR
- KMID: 1713121
- J Korean Med Sci.
- 2006 Dec;21(6):1070-1074.
- doi: 10.3346/jkms.2006.21.6.1070
Interleukin (IL)-12 activates T helper (Th) 1 cells to produce interferon (IFN)-gamma which inhibits atopic inflammation. IL-12 acts through interaction with its receptor, especially beta2 subunit. In several studies, the... -
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- A Statistical Analysis of SNPs, In-Dels, and Their Flanking Sequences in Human Genomic Regions
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Shin SW, Kim YJ, Kim BD
- KMID: 2166258
- Genomics Inform.
- 2007 Jun;5(2):68-76.
Due to the increasing interest in SNPs and mutational hot spots for disease traits, it is becoming more important to define and understand the relationship between SNPs and their flanking... -
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