- Year-in-Review of Lung Cancer
-
Son JW
- KMID: 1842908
- Tuberc Respir Dis.
- 2012 Sep;73(3):137-142.
- doi: 10.4046/trd.2012.73.3.137
In the last several years, we have made slow but steady progress in understanding molecular biology of lung cancer. This review is focused on advances in understanding the biology of... -
- CITED
-
- Close
- SHARE
-
- Close
- Application of Long Non-coding RNAs in Gastric Cancer
-
Lee SK
- KMID: 2439827
- Korean J Helicobacter Up Gastrointest Res.
- 2018 Sep;18(3):174-179.
- doi: 10.7704/kjhugr.2018.18.3.174
Gastric cancer remains a big problem in terms of incidence or mortality; various mechanisms to explain its development and progression have been studied. Recently, long non-coding RNAs (lncRNAs) have been... -
- CITED
-
- Close
- SHARE
-
- Close
- A Novel Type of Non-coding RNA, nc886, Implicated in Tumor Sensing and Suppression
-
Lee YS
- KMID: 2009143
- Genomics Inform.
- 2015 Jun;13(2):26-30.
- doi: 10.5808/GI.2015.13.2.26
nc886 (=vtRNA2-1, pre-miR-886, or CBL3) is a newly identified non-coding RNA (ncRNA) that represses the activity of protein kinase R (PKR). nc886 is transcribed by RNA polymerase III (Pol III)... -
- CITED
-
- Close
- SHARE
-
- Close
- Small Non-coding Transfer RNA-Derived RNA Fragments (tRFs): Their Biogenesis, Function and Implication in Human Diseases
-
Fu Y, Lee I, Lee YS, Bao X
- KMID: 2166523
- Genomics Inform.
- 2015 Dec;13(4):94-101.
- doi: 10.5808/GI.2015.13.4.94
tRNA-derived RNA fragments (tRFs) are an emerging class of non-coding RNAs (ncRNAs). A growing number of reports have shown that tRFs are not random degradation products but are functional ncRNAs... -
- CITED
-
- Close
- SHARE
-
- Close
- Select Macrophage Noncoding RNAs of Interest in Cardiovascular Disease
-
Enchill Z, Lantz C, Thorp EB
- KMID: 2470807
- J Lipid Atheroscler.
- 2020 Jan;9(1):153-161.
- doi: 10.12997/jla.2020.9.1.153
Cardiovascular disease remains a leading cause of morbidity and mortality worldwide. Aspects of disease severity that are associated with heightened inflammation, such as during atherosclerosis or after myocardial infarction, are... -
- CITED
-
- Close
- SHARE
-
- Close
- An Emerging Role for Circular RNAs in Osteoarthritis
-
Yu CX, Sun S
- KMID: 2407857
- Yonsei Med J.
- 2018 May;59(3):349-355.
- doi: 10.3349/ymj.2018.59.3.349
Circular RNAs (circRNAs) are currently classed as non-coding RNAs that, unlike the better known canonical linear RNAs, form a covalently closed continuous loop without 5′ or 3′ polarities. With the... -
- CITED
-
- Close
- SHARE
-
- Close
- The Role of MicroRNAs in Regulatory T Cells and in the Immune Response
-
Ha TY
- KMID: 2150690
- Immune Netw.
- 2011 Feb;11(1):11-41.
- doi: 10.4110/in.2011.11.1.11
The discovery of microRNA (miRNA) is one of the major scientific breakthroughs in recent years and has revolutionized current cell biology and medical science. miRNAs are small (19~25nt) noncoding RNA... -
- CITED
-
- Close
- SHARE
-
- Close
- MicroRNAs in Human Diseases: From Cancer to Cardiovascular Disease
-
Ha TY
- KMID: 2150701
- Immune Netw.
- 2011 Jun;11(3):135-154.
- doi: 10.4110/in.2011.11.3.135
The great discovery of microRNAs (miRNAs) has revolutionized current cell biology and medical science. miRNAs are small conserved non-coding RNA molecules that post-transcriptionally regulate gene expression by targeting the 3'... -
- CITED
-
- Close
- SHARE
-
- Close
- Current Status and Strategy of microRNA Research for Cartilage Development and Osteoarthritis Pathogenesis
-
Asahara H
- KMID: 2350807
- J Bone Metab.
- 2016 Aug;23(3):121-127.
- doi: 10.11005/jbm.2016.23.3.121
MicroRNAs (miRNAs), which are small (~21 nucleotides) non-coding RNAs, are important players in endochondral ossification, articular cartilage homeostasis, and arthritis pathogenesis. Comprehensive and genetic analyses of cartilage-specific or cartilage-related miRNAs... -
- CITED
-
- Close
- SHARE
-
- Close
- Identification of Caenorhabditis elegans MicroRNA Targets Using a Kernel Method
-
Lee WJ, Nam JW, Kim SK, Zhang BT
- KMID: 1572614
- Genomics Inform.
- 2005 Mar;3(1):15-23.
BACKGROUND: MicroRNAs (miRNAs)are a class of noncoding RNAs found in various organisms such as plants and mammals. However, most of the mRNAs regulated by miRNAs are unknown. Furthermore, miRNA targets... -
- CITED
-
- Close
- SHARE
-
- Close
- Noncoding RNAs as therapeutic targets in early stage diabetic kidney disease
-
Kato M
- KMID: 2447159
- Kidney Res Clin Pract.
- 2018 Sep;37(3):197-209.
- doi: 10.23876/j.krcp.2018.37.3.197
Diabetic kidney disease (DKD) is a major renal complication of diabetes that leads to renal dysfunction and end-stage renal disease (ESRD). Major features of DKD include accumulation of extracellular matrix... -
- CITED
-
- Close
- SHARE
-
- Close
- Roles of Long Non-Coding RNAs on Tumorigenesis and Glioma Development
-
Park JY, Lee JE, Park JB, Yoo H, Lee SH, Kim JH
- KMID: 1734662
- Brain Tumor Res Treat.
- 2014 Apr;2(1):1-6.
- doi: 10.14791/btrt.2014.2.1.1
More than 98% of eukaryotic transcriptomes are composed of non-coding RNAs with no functional protein-coding capacity. Those transcripts also include tens of thousands of long non-coding RNAs (lncRNAs) which are... -
- CITED
-
- Close
- SHARE
-
- Close
- Regulation Mechanism of Long Noncoding RNAs in Colon Cancer Development and Progression
-
Tang X, Qiao X, Chen C, Liu Y, Zhu J, Liu J
- KMID: 2450186
- Yonsei Med J.
- 2019 Apr;60(4):319-325.
- doi: 10.3349/ymj.2019.60.4.319
Colorectal cancer (CRC) is the second most common cause of cancer-related death worldwide, and its high rates of relapse and metastasis are associated with a poor prognosis. Despite extensive research,... -
- CITED
-
- Close
- SHARE
-
- Close
- The Function of the Vitamin D Receptor and a Possible Role of Enhancer RNA in Epigenomic Regulation of Target Genes: Implications for Bone Metabolism
-
Sawatsubashi S, Nishimura , Mori J, Kouzmenko , Kato S
- KMID: 2440639
- J Bone Metab.
- 2019 Feb;26(1):3-12.
- doi: 10.11005/jbm.2019.26.1.3
Vitamin D (VD) is essential for bone health, and VD or its analogues are widely used in clinics to ameliorate bone loss. The targets and mode of VD anti-osteoporotic actions... -
- CITED
-
- Close
- SHARE
-
- Close
- Regulation and Role of EZH2 in Cancer
-
Yamaguchi , Hung MC
- KMID: 2167686
- Cancer Res Treat.
- 2014 Jul;46(3):209-222.
Polycomb repressive complex 2 (PRC2) is the epigenetic regulator that induces histone H3 lysine 27 methylation (H3K27me3) and silences specific gene transcription. Enhancer of zeste homolog 2 (EZH2) is an... -
- CITED
-
- Close
- SHARE
-
- Close
- Expression Patterns of Circular RNAs from Primary Kinase Transcripts in the Mammary Glands of Lactating Rats
-
Zhang C, Wu H, Wang Y, Zhao Y, Fang X, Chen C, Chen H
- KMID: 2407570
- J Breast Cancer.
- 2015 Sep;18(3):235-241.
- doi: 10.4048/jbc.2015.18.3.235
PURPOSE: Circular RNAs (circRNAs), a novel class of RNAs, perform important functions in biological processes. However, the role of circRNAs in the mammary gland remains unknown. The present study is... -
- CITED
-
- Close
- SHARE
-
- Close
- Nitric oxide in liver fibrosis: The role of inducible nitric oxide synthase
-
Iwakiri Y
- KMID: 2359812
- Clin Mol Hepatol.
- 2015 Dec;21(4):319-325.
- doi: 10.3350/cmh.2015.21.4.319
The inducible form of nitric oxide synthase (iNOS) is expressed in hepatic cells in pathological conditions. Its induction is involved in the development of liver fibrosis, and thus iNOS could... -
- CITED
-
- Close
- SHARE
-
- Close
- Hepatitis B virus X protein-mediated non-coding RNA aberrations in the development of human hepatocellular carcinoma
-
Zhang B, Han S, Feng B, Chu X, Chen L, Wang R
- KMID: 2375023
- Exp Mol Med.
- 2017 Feb;49(2):e293.
- doi: 10.1038/emm.2016.177
Hepatitis B virus (HBV) has an important role in the development of human hepatocellular carcinoma (HCC). Accumulated evidence has shown that HBV-encoded X protein (HBx) can induce both genetic alterations... -
- CITED
-
- Close
- SHARE
-
- Close
- MicroRNA-1 in Cardiac Diseases and Cancers
-
Li J, Dong X, Wang Z, Wu J
- KMID: 2285532
- Korean J Physiol Pharmacol.
- 2014 Oct;18(5):359-363.
- doi: 10.4196/kjpp.2014.18.5.359
MicroRNAs (miRs) are endogenous approximately22-nt non-coding RNAs that participate in the regulation of gene expression at post-transcriptional level. MiR-1 is one of the muscle-specific miRs, aberrant expression of miR-1 plays... -
- CITED
-
- Close
- SHARE
-
- Close
- The Epigenetics of Triple-Negative and Basal-Like Breast Cancer: Current Knowledge
-
Temian DC, Pop LA, Irimie AI, Berindan-Neagoe I
- KMID: 2421363
- J Breast Cancer.
- 2018 Sep;21(3):233-243.
- doi: 10.4048/jbc.2018.21.e41
Breast cancer has the highest incidence among all malignancies diagnosed in women. Therapies have significantly improved over the years due to extensive molecular and clinical research; in a large number... -
- CITED
-
- Close
- SHARE
-
- Close
