- Craving and treatment in smoking
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Kim MH, Min S
- KMID: 2190424
- J Korean Med Assoc.
- 2011 Apr;54(4):401-408.
- doi: 10.5124/jkma.2011.54.4.401
Craving has been well known to be the most important clinical phenomenon in smoking cessation treatment and one that physicians always encounter. For successful and prolonged abstinence, understanding, evaluation, and... -
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- Changes in the Lacrimal Excretory System Depending on the Administration Mode of Brimonidine Tartrate: Spray vs. Irrigation
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Yang HS, Oh DE
- KMID: 2214568
- J Korean Ophthalmol Soc.
- 2011 May;52(5):511-518.
- doi: 10.3341/jkos.2011.52.5.511
PURPOSE: To investigate the effects of 0.15% brimonidine tartrate ophthalmic solution spray on the luminal changes in the nasolacrimal excretory system. METHODS: A prospective study was performed on 52 eyes in... -
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- Renewed 2015 Clinical Practice Guidelines for Management of Hepatitis C by Korean Association for the Study of the Liver; What Has Been Changed? - Treatment of Chronic Hepatitis C Genotype 1
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Park SH
- KMID: 2373411
- Korean J Gastroenterol.
- 2016 Mar;67(3):127-131.
- doi: 10.4166/kjg.2016.67.3.127
The introduction of direct-acting antiviral agents (DAAs) has markedly improved the sustained virological response (SVR) rates in patients with chronic hepatitis C. Currently, four classes of DAAs targeting three HCV... -
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- The Antimydriatic Effect of Brimonidine 0.15% on the Dark-adapted Pupil in Dark Brown Irides
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Rho SS, Yang HS, Lew HM, Ahn JH
- KMID: 2337690
- J Korean Ophthalmol Soc.
- 2008 Oct;49(10):1649-1657.
PURPOSE: To analyze the effect of the daily use of brimonidine tartrate 0.15% on the dark-adapted pupil diameter in dark brown irides. METHODS: Twenty-five healthy volunteers administered brimonidine tartrate 0.15% to... -
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- Prophylactic Effect of Brimonidine 0.15% on IOP Elevation After Intravitreal Triamcinolone Acetonide Injection
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Lee MW, Kyung SE, Chang MH
- KMID: 2211704
- J Korean Ophthalmol Soc.
- 2008 May;49(5):743-752.
- doi: 10.3341/jkos.2008.49.5.743
PURPOSE: The purpose of this study was to investigate the prophylactic effect of brimonidine 0.15% on intraocular pressure (IOP) elevation and the risk factors for its elevation after intravitreal triamcinolone... -
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- The efficacy of 0.2% brimonidine for preventing intraocular pressure rise following argon laser trabeculoplasty
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Ma YR, Lee BH, Yang KJ, Park YG
- KMID: 1127507
- Korean J Ophthalmol.
- 1999 Dec;13(2):78-84.
- doi: 10.3341/kjo.1999.13.2.78
Brimonidine tartrate of 0.5% was identified as the most effective and safe dose for acute intraocular pressure (IOP) lowering. The efficacy of brimonidine tartrate 0.2% in preventing IOP elevation after... -
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- Smoking Cessation Rate and Related Factors of Varenicline in Clinical Practice
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Song B, Yun WS, Choi EY, Cheong YS, Park EW
- KMID: 2304312
- Korean J Fam Med.
- 2011 Feb;32(2):112-119.
- doi: 10.4082/kjfm.2011.32.2.112
BACKGROUND: Varenicline is recently known as smoking cessation medicine has no results of researches conducted in the actual practice settings except for incipient clinical trials. This research attempted to analyze... -
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- Comparison of antiallodynic effect of intrathecal morphine, brimonidine and rilmenidine between neuritis and ligation injury induced neuropathic pain
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Kim YK, Park JY, Hwang JH
- KMID: 2236530
- Korean J Anesthesiol.
- 2009 Apr;56(4):425-432.
- doi: 10.4097/kjae.2009.56.4.425
BACKGROUND: Mechanical allodynia is generally resulted from nerve damage by direct injury or inflammation. Thus, this study was designed to compare the antiallodynic effect of morphine, brimonidine and rilmenidine in... -
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- Effect of Multi-modal Interventions for Smoking Cessation in a University Setting: A Short Course of Varenicline, Financial Incentives, E-mail and Short Message Service
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Cheong YS, Ahn SH
- KMID: 2235671
- Korean J Fam Med.
- 2010 May;31(5):355-360.
- doi: 10.4082/kjfm.2010.31.5.355
BACKGROUND: Varenicline is known to have higher effect for smoking cessation than existing pharmacotherapies, including Bupropion and Nicotine replacement therapy, however, it can also bring about adverse effects such as... -
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- Adherence to Varenicline and Abstinence Rates for Quitting Smoking in a Private Health Promotion Center-Based Smoking Cessation Clinic
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Lee JY, Kim MJ, Jun HJ, Kang M, Park AR, Oh DE, Choi YH, Hwang JH
- KMID: 2319816
- Tuberc Respir Dis.
- 2012 May;72(5):426-432.
BACKGROUND: Varenicline is an effective smoking cessation aid. However, smokers prescribed with varenicline do not always receive varenicline for 12 weeks, as recommended. This study analyzed the subjects who received... -
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- Effect of IN-1130, a Novel Transforming Growth Factor-beta Type I Receptor Kinase (ALK5) Inhibitor, on a Rat Model of Peyronie's Disease Induced by Repeated Intratunical Injections of Fibrin
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Piao S, Tumurbaatar M, Oh JH, Park SH, Suh JK, Ryu JK
- KMID: 2298783
- Korean J Androl.
- 2009 Aug;27(2):82-88.
PURPOSE: Transforming growth factor-beta1 (TGF-beta1) has been known to be involved in the pathogenesis of Peyronie's disease (PD). In the present study, we investigated the therapeutic effect of IN-1130, a... -
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- Activin Receptor-Like Kinase 5 Inhibitor Attenuates Fibrosis in Fibroblasts Derived from Peyronie's Plaque
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Jang JH, Ryu JK, Suh JK
- KMID: 1988823
- Korean J Urol.
- 2012 Jan;53(1):44-49.
- doi: 10.4111/kju.2012.53.1.44
PURPOSE: Transforming growth factor-beta1 (TGF-beta1) is the key fibrogenic cytokine associated with Peyronie's disease (PD). The aim of this study was to determine the antifibrotic effect of 3-((5-(6-Methylpyridin-2-yl)-4-(quinoxalin-6-yl)-1H-imidazol-2-yl) methyl)benzamide (IN-1130),... -
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- Inhibitory effect of Suaeda asparagoides (Miq.) extract on the motility of rat gastric antrum is mediated by beta-adrenoceptor
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Endale M, Song JC, Rhee MH, Liu KH, Kim TK, Kwon JG, Park KS, Chung KM, Kim TW
- KMID: 1444964
- Lab Anim Res.
- 2011 Dec;27(4):317-325.
- doi: 10.5625/lar.2011.27.4.317
Suaeda asparagoides (Miq.) has long been used as a Korean folk herbal medicine for the treatment of functional gastrointestinal disorders. However, reports on its pharmacological activity on gastrointestinal motility are... -
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- The Effect of Brimonidine on Transepithelial Resistance in a Human Retinal Pigment Epithelial Cell Line
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Park JH, Kim SJ, Yu HG
- KMID: 945988
- Korean J Ophthalmol.
- 2010 Jun;24(3):169-172.
- doi: 10.3341/kjo.2010.24.3.169
PURPOSE: To investigate the effects of brimonidine, an alpha-2-adrenergic agonist, on barrier function in ARPE-19 cells by measuring transepithelial resistance (TER). METHODS: ARPE-19 cells were cultured into a confluent monolayer... -
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- Antinociceptive Interactions between Intrathecal Gabapentin and MK801 or NBQX in Rat Formalin Test
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Yoon MH, Bae HB, Choi JI
- KMID: 1095209
- J Korean Med Sci.
- 2005 Apr;20(2):307-312.
- doi: 10.3346/jkms.2005.20.2.307
Antagonists for spinal N-methyl-D-aspartate (NMDA) and amino-hydroxy-methtyl-isoxazolepropionate (AMPA) receptors are effective in attenuating acute nociception or injury-induced hyperalgesia. The antinociception of spinal gabapentin is developed in injury-induced hyperalgesia without affecting... -
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- Inhibition of Hypoxic Pulmonary Vasoconstriction of Rats by Carbon Monoxide
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Yoo HY, Park SJ, Bahk JH, Kim SJ
- KMID: 2157842
- J Korean Med Sci.
- 2010 Oct;25(10):1411-1417.
- doi: 10.3346/jkms.2010.25.10.1411
Hypoxic pulmonary vasoconstriction (HPV), a unique response of pulmonary circulation, is critical to prevent hypoxemia under local hypoventilation. Hypoxic inhibition of K+ channel is known as an important O2-sensing mechanism... -
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- Light-controlled relaxation of the rat penile corpus cavernosum using NOBL-1, a novel nitric oxide releaser
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Hotta Y, Ieda N, Fukamoto A, Kataoka T, Kawade Y, Maeda Y, Nakagawa H, Kimura K
- KMID: 2426497
- Investig Clin Urol.
- 2016 May;57(3):215-220.
- doi: 10.4111/icu.2016.57.3.215
PURPOSE: To investigate whether relaxation of the rat penile corpus cavernosum could be controlled with NOBL-1, a novel, light-controllable nitric oxide (NO) releaser. MATERIALS AND METHODS: Fifteen-week-old male Wistar-ST rats were... -
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- Cinnamyl alcohol attenuates vasoconstriction by activation of K+ channels via NO-cGMP-protein kinase G pathway and inhibition of Rho-kinase
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Kang YH, Yang IJ, Morgan KG, Shin HM
- KMID: 1402319
- Exp Mol Med.
- 2012 Dec;44(12):749-755.
Cinnamyl alcohol (CAL) is known as an antipyretic, and a recent study showed its vasodilatory activity without explaining the mechanism. Here we demonstrate the vasodilatory effect and the mechanism of... -
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