- LRIG1 Enhances Chemosensitivity by Modulating BCL-2 Expression and Receptor Tyrosine Kinase Signaling in Glioma Cells
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Guo Z, Chen Q, Liu B, Tian D, Zhang S, Li M
- KMID: 1799481
- Yonsei Med J.
- 2014 Sep;55(5):1196-1205.
- doi: 10.3349/ymj.2014.55.5.1196
PURPOSE: Leucine-rich repeats and immunoglobulin-like domains 1 (LRIG1) are an inhibitor of receptor tyrosine kinases (RTKs) that was discovered in recent years, and many studies showed that LRIG1 is a... -
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- Immunohistochemical Expression of Bcl-2, Bcl-xL, Bax, p53 Proteins in Gastric Adenoma and Adenocarcinoma
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Lee DS, Kang SB, Baek JT, Nam SW, Lee KM, Ahn BM, Lee EH, Han SW, Chung IS
- KMID: 772786
- Korean J Gastroenterol.
- 2005 Jun;45(6):394-400.
BACKGROUND/AIMS: The aim of this study was to investigate the immunohistochemical expression of bcl-2, bcl-xL, bax, and p53 proteins according to the pathological parameters such as grade of dysplasia,... -
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- Immunohistochemical Localization of Bcl-2 in the Spinal Cords of Rats with Experimental Autoimmune Encephalomyelitis
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Moon CJ, Lee YD, Shin TK
- KMID: 1097344
- J Vet Sci.
- 2002 Dec;3(4):279-283.
We examined the localization of the anti-apoptotic molecule Bcl-2 in the spinal cords of Lewis rats with experimental autoimmune encephalomyelitis (EAE). Western blot analysis showed that Bcl-2 was constitutively expressed... -
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- COX-2 inhibits anoikis by activation of the PI-3K/Akt pathway in human bladder cancer cells
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Choi EM, Kwak SJ, Kim YM, Ha KS, Kim JI, Lee SW, Han JA
- KMID: 1056232
- Exp Mol Med.
- 2005 Jun;37(3):199-203.
Cyclooxygenase-2 (COX-2) has been reported to be associated with tumor development and progression as well as to protect cells from apoptosis induced by various cellular stresses. Through a tetracycline-regulated COX-2... -
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- Tissue Microarray Analysis of Fas and FasL Expressions in Human Non-small Cell Lung Carcinomas; with Reference to the p53 and bcl-2 Overexpressions
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Myong NH
- KMID: 1781759
- J Korean Med Sci.
- 2005 Oct;20(5):770-776.
- doi: 10.3346/jkms.2005.20.5.770
Lack of surface Fas expression is a main route for apoptotic resistance which is considered an important mechanism of tumorigenesis and tumor progression. Fas and FasL expressions in 110 non-small... -
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- Time Dependent Bladder Apoptosis Induced by Acute Bladder Outlet Obstruction and Subsequent Emptying is Associated with Decreased MnSOD Expression and Bcl-2/Bax Ratio
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Li WJ, Shin MK, Oh SJ
- KMID: 1779237
- J Korean Med Sci.
- 2010 Nov;25(11):1652-1656.
- doi: 10.3346/jkms.2010.25.11.1652
Ischemia/reperfusion (I/R) injury-induced oxidative stress plays an important role in the functional impairment of the bladder following acute bladder outlet obstruction (BOO) via induction of apoptosis. The purpose of this... -
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- Expression of Cyclooxygenase-2 and Bcl-2 in Human Gastric Adenomas
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Park JH, Kang KH, Kim SH, Lee JH, Cho CM, Kweon YO, Kim SK, Choi YH, Bae HI, Kim MS
- KMID: 1782230
- Korean J Intern Med.
- 2005 Sep;20(3):198-204.
- doi: 10.3904/kjim.2005.20.3.198
BACKGROUND: Cyclooxygenase (COX) -2 is the rate-limiting enzyme in prostaglandin synthesis. An increased expression has been implicated in the development and progression of human gastric cancers and colorectal adenomas and... -
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