- Differential Expression of TGF-beta Isoforms During Differentiation of HaCaT Human Keratinocyte Cells: Implication for the Separate Role in Epidermal Differentiation
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Cho HR, Hong SB, Kim YI, Lee JW, Kim NI
- KMID: 1778568
- J Korean Med Sci.
- 2004 Dec;19(6):853-858.
- doi: 10.3346/jkms.2004.19.6.853
The three mammalian isoforms of transforming growth factor-beta (TGF-beta1, beta2, beta3) are potent regulators of cell growth, differentiation, and extracellular matrix deposition. To study their role in skin differentiation, we... -
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- Expression of Ca2+-dependent Synaptotagmin Isoforms in Mouse and Rat Parotid Acinar Cells
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Jo H, Byun HM, Kim JH, Kim MS, Kim SH, Hong JH, Seo JT, Lee SI, Shin DM, Son HK
- KMID: 1715875
- Yonsei Med J.
- 2006 Feb;47(1):70-77.
- doi: 10.3349/ymj.2006.47.1.70
Synaptotagmin is a Ca2+ sensing protein, which triggers a fusion of synaptic vesicles in neuronal transmission. Little is known regarding the expression of Ca2+ - dependent synaptotagmin isoforms and their... -
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- Increased methylation of the cytosolic 20-kD protein is accompanied by liver regeneration in a hepatectomized rat
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Kwon SY, Kim S, Lee K, Kim TJ, Lee SH, Lee KM, Park GH
- KMID: 755670
- Exp Mol Med.
- 2004 Feb;36(1):85-92.
Arginine methylation has been implicated in the signal transduction pathway leading to cell growth. Here we show that a regenerating rat liver following partial hepatectomy exhibited elevated methyltransferase activity as... -
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- Morphine Postconditioning Attenuates ICAM-1 Expression on Endothelial Cells
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Min TJ, Kim JI, Kim JH, Noh KH, Kim TW, Kim WY, Lee YS, Park YC
- KMID: 1782121
- J Korean Med Sci.
- 2011 Feb;26(2):290-296.
- doi: 10.3346/jkms.2011.26.2.290
The purpose of this study is to determine 1) whether morphine postconditiong (MPostC) can attenuate the intercellular adhesion molecules-1 (ICAM-1) expression after reoxygenation injury and 2) the subtype(s) of the... -
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- An alternatively spliced form of Met receptor is tumorigenic
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Lee JH, Gao CF, Lee CC, Kim MD, Vande Woude GF
- KMID: 1098091
- Exp Mol Med.
- 2006 Oct;38(5):565-573.
The Met tyrosine kinase receptor is a widely expressed molecule, which mediates pleiotropic cellular responses following activation by its ligand, hepatocyte growth factor/scatter factor (HGF/SF). Previously, one of the authors... -
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- Fibroblast growth factor receptor isotype expression and its association with overall survival in patients with hepatocellular carcinoma
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Lee HJ, Kang HJ, Kim KM, Yu ES, Kim KH, Kim SM, Kim TW, Shim JH, Lim YS, Lee HC, Chung YH, Lee YS
- KMID: 2155292
- Clin Mol Hepatol.
- 2015 Mar;21(1):60-70.
- doi: 10.3350/cmh.2015.21.1.60
BACKGROUND/AIMS: Fibroblast growth factor signaling is involved in hepatocarcinogenesis. The aim of this study was to determine the fibroblast growth factor receptor (FGFR) isotype expression in hepatocellular carcinoma (HCC) and... -
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- Trichostatin A induces apoptosis in lung cancer cells via simultaneous activation of the death receptor-mediated and mitochondrial pathway
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Kim HR, Kim EJ, Yang SH, Jeong ET, Park C, Lee JH, Youn MJ, So HS, Park R
- KMID: 1115939
- Exp Mol Med.
- 2006 Dec;38(6):616-624.
Trichostatin A (TSA), originally developed as an antifungal agent, is one of potent histone deacetylase (HDAC) inhibitors, which are known to cause growth arrest and apoptosis induction of transformed cells,... -
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- Evaluation of HER2/neu Status by Real-Time Quantitative PCR in Breast Cancer
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Kim YR, Choi JR, Song KS, Chong WH, Lee HD
- KMID: 1105103
- Yonsei Med J.
- 2002 Jun;43(3):335-340.
- doi: 10.3349/ymj.2002.43.3.335
Over-expression of the human epidermal growth factor receptor-2 (HER2/neu) has been observed in many cancers, and is associated with a poor prognosis. Recent adjuvant treatment with anti-HER2 monoclonal antibodies in... -
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- The expression and localization of inhibin isotypes in mouse testis during postnatal development
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Kim Y, Kim JS, Song MS, Seo HS, Kim JC, Bae CS, Kim S, Shin T, Kim SH, Moon C
- KMID: 1104908
- J Vet Sci.
- 2008 Dec;9(4):345-349.
- doi: 10.4142/jvs.2008.9.4.345
Inhibin, which is important for normal gonadal function, acts on the pituitary gonadotropins to suppress folliclestimulating hormone (FSH) secretion. The level and cellular localization of the inhibin isotypes, alpha, beta(A)... -
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- In vitro model of atherosclerosis using coculture of arterial wall cells and macrophage
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Wada Y, Sugiyama A, Kohro T, Kobayashi , Takeya M, Naito M, Kodama T
- KMID: 1114562
- Yonsei Med J.
- 2000 Dec;41(6):740-755.
- doi: 10.3349/ymj.2000.41.6.740
In order to determine the precise mechanism of the interactions between different types of cells, which are common phenomena in tissues and organs, the importance of coculture techniques are becoming... -
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