- Proteomic applications of surface plasmon resonance biosensors: analysis of protein arrays
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Yuk JS, Ha KS
- KMID: 1033095
- Exp Mol Med.
- 2005 Feb;37(1):1-10.
Proteomics is one of the most important issues in the post-genomic area, because it can greatly contribute to identifying protein biomarkers for disease diagnosis and drug screening. Protein array is... -
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- Application of Proteomics and Protein Chip Analysis in the Diagnosis of Neurodegenerative Disorders
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Ryu W, Choi C
- KMID: 2185762
- J Korean Neurol Assoc.
- 2003 Dec;21(6):584-599.
As we face an increase of the adult population suffering from dementia, a typical senile disorder, it is imperative to develop appropriate tools for early detection and differential diagnosis of... -
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- QCanvas: An Advanced Tool for Data Clustering and Visualization of Genomics Data
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Kim N, Park H, He N, Lee HY, Yoon S
- KMID: 2053307
- Genomics Inform.
- 2012 Dec;10(4):263-265.
- doi: 10.5808/GI.2012.10.4.263
We developed a user-friendly, interactive program to simultaneously cluster and visualize omics data, such as DNA and protein array profiles. This program provides diverse algorithms for the hierarchical clustering of... -
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- Molecular Biologic Techniques in Cytopathologic Diagnosis
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Hwang TS
- KMID: 1472615
- Korean J Pathol.
- 2009 Oct;43(5):387-392.
- doi: 10.4132/KoreanJPathol.2009.43.5.387
Molecular diagnosis is an application of the knowledge on molecular mechanisms of disease to diagnosis, therapeutic decision-making, and prognostication. Basically any molecular diagnostic technique could be used in molecular diagnostic... -
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- Characterization of Pv92, a Novel Merozoite Surface Protein of Plasmodium vivax
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Lee SK, Wang B, Han JH, Nyunt MH, Muh F, Chootong P, Ha KS, Park WS, Hong SH, Park JH, Han ET
- KMID: 2353566
- Korean J Parasitol.
- 2016 Aug;54(4):385-391.
- doi: 10.3347/kjp.2016.54.4.385
The discovery and understanding of antigenic proteins are essential for development of a vaccine against malaria. In Plasmodium falciparum, Pf92 have been characterized as a merozoite surface protein, and this... -
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- Protein Expression of Cyclin B1, Transferrin Receptor, and Fibronectin Is Correlated with the Prognosis of Adrenal Cortical Carcinoma
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Moon SJ, Kim JH, Kong SH, Shin CS
- KMID: 2471729
- Endocrinol Metab.
- 2020 Mar;35(1):132-141.
- doi: 10.3803/EnM.2020.35.1.132
BACKGROUND: Adrenal cortical carcinoma (ACC) is a rare cancer with a variable prognosis. Several prognostic factors of ACC have been previously reported, but a proteomic analysis has not yet been... -
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- Identification of the Thioredoxin-Like 2 Autoantibody as a Specific Biomarker for Triple-Negative Breast Cancer
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Chung JM, Jung Y, Kim YP, Song J, Kim S, Kim JY, Kwon M, Yoon JH, Kim MD, Lee JK, Chung DY, Lee SY, Kang J, Kang HC
- KMID: 2441872
- J Breast Cancer.
- 2018 Mar;21(1):87-90.
- doi: 10.4048/jbc.2018.21.1.87
Triple-negative breast cancer (TNBC) has a higher risk of death within 5 years of being diagnosed than the other forms of breast cancer. It is the second leading cause of... -
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- Unfolded Histidine-Tagged Protein is Immobilized to Nitrilotriacetic Acid-Nickel Beads, But Not the Nickel-Coated Glass Slide
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Cho M, Ahn S, Park H
- KMID: 1512149
- Genomics Inform.
- 2006 Sep;4(3):133-136.
The adsorption of proteins on the surface of glass slides is essential for construction of protein chips. Previously, we prepared a nickel-coated plate by the spin-coating method for immobilization of... -
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- Development of Protein Chip for Diagnosis of Chlamydophia Pneumoniae
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Kim WJ, Lee HY, Lee SJ, Jung SH, Yuk JS, Ha KS, Jung KS
- KMID: 1719366
- Tuberc Respir Dis.
- 2006 Apr;60(4):412-418.
- doi: 10.4046/trd.2006.60.4.412
BACKGROUND: The diagnosis of chlamydial infection is based on serology. The current gold standard of diagnosis is MIF(microimmunofluorescence), but this modality is subjective and time-consuming. Protein microarray with using a... -
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- HER-2/neu Oncogene Amplification by Chromogenic in situ Hybridization in 130 Breast Cancers Using Tissue Microarray and Clinical Follow-up Studies
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Chang E, Lee A, Lee E, Lee H, Shin O, Oh S, Kang C
- KMID: 1786817
- J Korean Med Sci.
- 2004 Jun;19(3):390-396.
- doi: 10.3346/jkms.2004.19.3.390
Determining of HER-2/neu oncogene amplification has become clinically important for managing breast cancer. Fluorescent in situ hybridization (FISH) and immunohistochemistry (IHC) are currently regarded as the standard methods. Chromogenic in... -
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- Investigation of Immune-Regulatory Effects of Mageumsan Hot Spring via Protein Microarray In Vitro
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Hahn HJ, Kim JS, Kim YH, Lee YB, Yu DS, Kim JW
- KMID: 2419174
- Ann Dermatol.
- 2018 Jun;30(3):322-330.
- doi: 10.5021/ad.2018.30.3.322
BACKGROUND: Empirical evidences for efficacy of hot spring (HS) water in inflammatory skin disorders have not been substantiated with sufficient, immunological “hard evidenceâ€. Mageumsan HS water, characterized by its weakly-alkaline... -
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- A study of APin-protein interactions using protein microarray
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Park JC, Park SH, Kim HJ, Park JT, Youn SH, Kim JW, Lee TY, Son HH
- KMID: 2175939
- J Korean Acad Conserv Dent.
- 2007 Sep;32(5):459-468.
- doi: 10.5395/JKACD.2007.32.5.459
Protein microarray or protein chips is potentially powerful tools for analysis of protein-protein interactions. APin cDNA was previously identified and cloned from a rat odontoblast cDNA library. The purpose of... -
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- BCL2 Regulation according to Molecular Subtype of Breast Cancer by Analysis of The Cancer Genome Atlas Database
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Hwang KT, Kim K, Chang JH, Oh S, Kim YA, Lee JY, Jung SH, Choi IS
- KMID: 2417855
- Cancer Res Treat.
- 2018 Jul;50(3):658-669.
- doi: 10.4143/crt.2017.134
PURPOSE: We investigated B-cell lymphoma 2 (BCL2) regulation across DNA, RNA, protein, and methylation status according to molecular subtype of breast cancer using The Cancer Genome Atlas (TCGA) database. MATERIALS AND... -
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- Anti-Enteric Neuronal Antibodies and the Irritable Bowel Syndrome
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Wood JD, Liu S, Drossman D, Ringel Y, Whitehead
- KMID: 2325863
- J Neurogastroenterol Motil.
- 2012 Jan;18(1):78-85.
BACKGROUND/AIMS: Functional gastrointestinal disorders are those in which no abnormal metabolic or physical processes, which can account for the symptoms, can be identified. The irritable bowel syndrome (IBS) is a... -
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- Development of Decision Tree Software and Protein Profiling using Surface Enhanced Laser Desorption/Ionization - Time of Flight - Mass Spectrometry (SELDI-TOF-MS) in Papillary Thyroid Cancer
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Yoon JK, Lee J, An YS, Park BN, Yoon SN
- KMID: 2139231
- Nucl Med Mol Imaging.
- 2007 Aug;41(4):299-308.
PURPOSE: The aim of this study was to develop a bioinformatics software and to test it in serum samples of papillary thyroid cancer using mass spectrometry (SELDI-TOF-MS). MATERIALS AND METHODS:... -
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- Expression of the Transmembrane Glycoprotein CD44s Is Potentially an Independent Predictor of Recurrence in Hepatocellular Carcinoma
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Ryu HS, Park SH, Lee KB, Shin E, Jang JJ
- KMID: 2135094
- Gut Liver.
- 2011 Jun;5(2):204-209.
BACKGROUND/AIMS: Cluster differentiation 44 standard isoform (CD44s) is a transmembrane glycoprotein. CD44s is a known prognostic factor in various cancers, due to its involvement in tumor cell growth, invasion and... -
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- Difference in Protein Markers According to the Survival of Sepsis Patients using Protein Chips
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Park MO, Lee HY, Son HJ, Sung JH, Lee SJ, Lee SJ, Ha KS, Kim WJ
- KMID: 2318893
- Tuberc Respir Dis.
- 2006 Jul;61(1):41-45.
BACKGROUND: Several clinical scoring systems are currently being used to predict the outcome of sepsis, but they all have certain limitations. Therefore, we sought to identify the proteomic biomarkers, with... -
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- The Effect of Caffeine on 3T3-L1 Adipocyte Differentiation : A Nutrigenomical Approach
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Kim MJ, Kim Y, Chung JH, Kim JW, Kim HK
- KMID: 2257587
- Korean J Nutr.
- 2005 Oct;38(8):649-655.
Nutrigenomics refers to research that investigates the interaction between nutrition and the human genome. Caffeine in tea and coffee is widely and routinely consumed by people. This study was performed... -
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- Circulating Levels of Adipokines Predict the Occurrence of Acute Graft-versus-host Disease
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Kim JS, You DB, Lim JY, Lee SE, Kim YJ, Kim HJ, Chung NG, Min CK
- KMID: 2168031
- Immune Netw.
- 2015 Apr;15(2):66-72.
- doi: 10.4110/in.2015.15.2.66
Currently, detecting biochemical differences before and after allogeneic stem cell transplantation (SCT) for improved prediction of acute graft-versus-host disease (aGVHD) is a major clinical challenge. In this pilot study, we... -
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- Quantitative measurement of serum allergen-specific IgE on protein chip
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Kim TE, Park SW, Cho NY, Choi SY, Yong TS, Nahm BH, Lee S, Noh G
- KMID: 1081465
- Exp Mol Med.
- 2002 May;34(2):152-158.
Type I allergy is an immunoglobulin E (IgE)-mediated hypersensitivity disease inflicting more than quarter of the world population. In order to identify allergen sources, skin provocation test and IgE serology... -
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