- Inhibition of voltage-dependent K⺠current in rabbit coronary arterial smooth muscle cells by the class Ic antiarrhythmic drug propafenone
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An JR, Li H, Seo MS, Park WS
- KMID: 2419009
- Korean J Physiol Pharmacol.
- 2018 Sep;22(5):597-605.
- doi: 10.4196/kjpp.2018.22.5.597
In this study, we demonstrated the inhibitory effect of the Class Ic antiarrhythmic agent propafenone on voltage-dependent K⺠(Kv) channels using freshly isolated coronary artery smooth muscle cells from rabbits.... -
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- A clinical observation on antiarrhythmic efficacy of propafenone for atrial fibrillation
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Kim YK, Park SH
- KMID: 2229200
- Korean Circ J.
- 1993 Feb;23(1):117-122.
- doi: 10.4070/kcj.1993.23.1.117
BACKGROUND: Propafenone is effective in the treatment of ventricular arrhythmias and paroxysmal supraventricular tachycardia. Propafenone has been shown to be also useful in preventing the recurrence of atrial fibrillation. But... -
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- A Concealed Brugada Electrocardiogram Pattern Revealed after Administering Propafenone to a Patient with Atrial Fibrillation
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Sim HH, Kwon NH, Baeg JY, Yun CY, Ahn SM, Oh YM, Kim YJ
- KMID: 1867320
- Korean J Med.
- 2014 Jan;86(1):70-73.
- doi: 10.3904/kjm.2014.86.1.70
Brugada syndrome is characterized by sudden cardiac death associated with ventricular tachyarrhythmia in patients without structural heart disease. We recently observed a case of concealed Brugada ECG pattern, which appeared... -
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- Clinical Effects of Propafenone and Disopyramide on Ventricular Premature Complexes: Double-Blind, Placebo-Controlled, Randomized Cross-Over Study
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Kim BO, Hong MG, Jang YS, Shim WH, Cho SY, Kim SS
- KMID: 2229180
- Korean Circ J.
- 1992 Apr;22(2):280-288.
- doi: 10.4070/kcj.1992.22.2.280
BACKGROUND: Propafenone is a new class Ic antiarrhythmic compound.This study was performed to evaluate the clinical efficacy and safety of propafenone by double-blind, placebo-controlled, randomized cross-over comparison of propafenone and... -
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- Electrophysiologic and long-term effects of propafenone on paroxysmal supraventricular tachycardia
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Choi YS, Sohn DW, Lee MM, Park YB, Seo JD, Lee YW
- KMID: 2229235
- Korean Circ J.
- 1993 Jun;23(3):440-447.
- doi: 10.4070/kcj.1993.23.3.440
BACKGROUND: Propafenone is a new class IC antiarrhythmic drug that has been found to be effective in both supraventricular and ventricular tachyarrhythmias. We studied the electrophysiologic and long-term effects of... -
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- A Case of Fatal Arrhythmia after Propafenone Overdose
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Kyong YY, Choi KH
- KMID: 2203442
- J Korean Soc Clin Toxicol.
- 2008 Dec;6(2):123-129.
A 36-year-old female was transferred to our emergency medical center with decreased mental status after a 6.0 g propafenone overdose because of domestic disturbance. She had no previous history of... -
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- Amiodarone Versus Propafenone to Treat Atrial Fibrillation after Coronary Artery Bypass Grafting: A Randomized Double Blind Controlled Trial
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Nemati MH, Astaneh B
- KMID: 2285806
- Korean J Thorac Cardiovasc Surg.
- 2016 Jun;49(3):177-184.
- doi: 10.5090/kjtcs.2016.49.3.177
BACKGROUND: Atrial fibrillation (AF) is one of the most common complications after cardiac surgery. Several therapeutic and preventive strategies have been introduced for postoperative AF, but the treatment and prophylaxis... -
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- Acute Effect of Intravenous Propafenone for Atrial Fibrillation Refractory to Transthoracic Electrical Cardioversion
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Choi JI, Kim YH, Kim SH, Hwang GN, Hong SJ, Choi CW, Park SM, Rha SW, Park SW, Lim DS, Sim WJ, Oh DJ, Ro YM
- KMID: 1938828
- Korean Circ J.
- 2002 Oct;32(10):878-883.
- doi: 10.4070/kcj.2002.32.10.878
BACKGROUND AND OBJECTIVES: Various intravenous (IV) antiarrhythmic drugs in patients with atrial fibrillation (AF) refractory to electrical cardiooversion have been attempted. We assessed the efficacy of IV propafenone in patients... -
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- A Case of Neonatal Atrial Flutter Treated by Propafenone after Fetal Echocardiographic Diagnosis
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Lee KH, Ha CW, Kim CH, Song MS, Sung MS
- KMID: 2335662
- J Korean Pediatr Soc.
- 2002 Jul;45(7):928-932.
Perinatal atrial flutter is a potentially lethal arrhythmia. Management of this disorder is difficult and controversial. Fetal atrial flutter is a serious and life threatening rhythm disorder particulary when it... -
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- Atrial Fibrillation Treated by Propafenone during Induction of General Anesthesia: A case report
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Chung JY, Kim BI, Lee MS
- KMID: 2299021
- Korean J Anesthesiol.
- 2003 Mar;44(3):418-422.
- doi: 10.4097/kjae.2003.44.3.418
We experienced a case of unexpected atrial fibrillation (AF) developed during induction of general anesthesia. The patient was a 71-year-old woman diagnosed with a cerebral aneurysm. She had no history... -
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- Wide QRS tachycardia during treatment with class ic antiarrhythmic agents in a patient with atrial fibrillation: report of 2 cases
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Shim JK, Lee DI, Chang BI, Shin HJ, Byun KH, Kim YW, Kim JH
- KMID: 2252730
- Korean J Med.
- 2003 Nov;65(Suppl 3):S727-S732.
Wide QRS tachycardia may represent a rare proarrhythmic effect of some antiarrhythmic agents. Class Ic antiarrhythmic agents produce rate- dependent ventricular conduction slowing due to use-dependent sodium channel blockade, causing... -
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- An Iatrogenically Unmasked Life Threatening Disease: Brugada Syndrome
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Ercan S, Oylumlu M, Altunbas G, Davutoglu
- KMID: 2224906
- Korean Circ J.
- 2013 Jun;43(6):426-428.
- doi: 10.4070/kcj.2013.43.6.426
Brugada syndrome is a life threatening disease that is usually overlooked during emergency service admissions. It is characterized by typical electrocardiography resembling right bundle branch block, static or dynamic ST-segment... -
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- Comparision of thr Efficacy of Propafenone and Flecainide in Patients with Atrial Fibrillation
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Kim DS, Koh CW, Cho HK, Kim TY, Ahn SK, Lee MH, Kim SS
- KMID: 2229069
- Korean Circ J.
- 1997 Sep;27(9):860-866.
- doi: 10.4070/kcj.1997.27.9.860
BACKGROUND: Atrial fibrillation is one of the most common cardiac arrhythmias which has been recieved relatively little attention until recently.Despite the variety of treatment modalities including drugs,surgery,catheter ablation and devices,the... -
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- Regulation of Antiarrhythmic Drug Propafenone Effects on the C-type KV1.4 Potassium Channel by PHo and K+
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Wang Z, Wang S, Li J, Jiang X, Wang N
- KMID: 1794411
- J Korean Med Sci.
- 2009 Feb;24(1):84-91.
- doi: 10.3346/jkms.2009.24.1.84
The effects of the antiarrhythmic drug propafenone at c-type kv1.4 channels in Xenopus laevis oocytes were studied with the two-electrode voltage-clamp techinique. Defolliculated oocytes (stage V-VI) were injected with transcribed... -
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- Insulin Treatment of Shock Induced by Acute Propafenone Toxicity Refractory to Sodium Bicarbonate Administration
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Yi HY, Lee JY
- KMID: 2332856
- J Korean Soc Emerg Med.
- 2010 Dec;21(6):906-909.
Propafenone is a Class Ic antidysrhythmic agent, used in the management of atrial fibrillation. This is also a calcium channel and a weak beta blocker. The conventional therapy of hypotension... -
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- Effects of Verapamil and Propafenone on Pacing-induced Atrial Electrophysiologic Remodeling
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Cho JG, Ahn YK, Park HW, Koh JS, Yang BR, Lee SH, Lee SH, Hong YJ, Kim NH, Kim W, Rhew JY, Yum JH, Kim JH, Jeong MH, Park JC, Kang JC
- KMID: 2172397
- Chonnam Med J.
- 2001 Dec;37(4):345-349.
It has been demonstrated that atrial fibrillation (AF) induces atrial electrophysiologic remodeling (AER) and AER is responsible for perpetuation of AF. The purpose of the present study was to determine... -
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- Supraventricular Tachycardia by Concealed Bypass Tract
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Lee KH
- KMID: 2377065
- Int J Arrhythm.
- 2017 Mar;18(1):38-42.
- doi: 10.18501/arrhythmia.2017.005
Concealed bypass tract (CBT) results from incomplete development of the atrioventricular (AV) annulus. CBT conducts only in a retrograde direction, and therefore does not cause pre-excitation on standard electrocardiograms. The... -
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- Differing Electrophysiological Effects of Various Antiarrhythmic Drugs on the Cardiac Chamber in Atrial Fibrillation
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Jang SY, Cho JG, Jung HK, Ki WJ, Lee KJ, Ko JS, Lee MG, Park KH, Sim DS, Yoon NS, Yoon HJ, Hong YJ, Park HW, Kim JH, Ahn Y, Jeong MH, Park JC, Kang JC
- KMID: 2259290
- Korean J Med.
- 2011 Jun;80(6):672-679.
BACKGROUND/AIMS: Long-term antiarrhythmic drug therapy remains the principal approach for suppressing atrial fibrillation (AF) and maintaining sinus rhythm. In this study, we examined the differing electrophysiological effects of various antiarrhythmic... -
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- Cost-Effectiveness of Rate- and Rhythm-Control Drugs for Treating Atrial Fibrillation in Korea
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Kim M, Kim W, Kim C, Joung B
- KMID: 2463794
- Yonsei Med J.
- 2019 Dec;60(12):1157-1163.
- doi: 10.3349/ymj.2019.60.12.1157
PURPOSE: Although the economic and mortality burden of atrial fibrillation (AF) is substantial, it remains unclear which treatment strategies for rate and rhythm control are most cost-effective. Consequently, economic factors... -
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