- Building the Frequency Profile of the Core Promoter Element Patterns in the Three ChromHMM Promoter States at 200bp Intervals: A Statistical Perspective
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Lent H, Lee KE, Park HS
- KMID: 2166531
- Genomics Inform.
- 2015 Dec;13(4):152-155.
- doi: 10.5808/GI.2015.13.4.152
Recently, the Encyclopedia of DNA Elements (ENCODE) Analysis Working Group converted data from ChIP-seq analyses from the Broad Histone track into 15 corresponding chromatic maps that label sequences with different... -
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- Promoter region searching and restriction map for ecoR I-J fragment of hyphantria cunea nuclear polyhedrosis virus genome DNA
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Park KJ, Lee HH
- KMID: 1688637
- J Korean Soc Virol.
- 1993 Mar;23(1):85-93.
No abstract available. -
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- Discovery and Evaluation of Polymorphisms in the AKT2 and AKT3 Promoter Regions for Risk of Korean Lung Cancer
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Sung JS, Park KH, Kim ST, Kim YH
- KMID: 1806245
- Genomics Inform.
- 2012 Sep;10(3):167-174.
- doi: 10.5808/GI.2012.10.3.167
AKT is a signal transduction protein that plays a central role in the tumorigenesis. There are 3 mammalian isoforms of this serine/threonine protein kinase-AKT1, AKT2, and AKT3-showing a broad tissue... -
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- Identification of Novel Genetic Variations in the Proximal Promoter of the Human Transporter, OCT2
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Choi JH
- KMID: 1893441
- Ewha Med J.
- 2011 Mar;34(1):9-13.
- doi: 10.12771/emj.2011.34.1.9
OBJECTIVES: Human organic cation transporter 2, OCT2(SLC22A2), highly expressed on the renal proximal tubular cells, plays an important role in the renal excretion of endogenous and exogenous organic cations including... -
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- Identification and Functional Characterization of Novel Genetic Variations in the OCTN1 Promoter
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Park HJ, Choi JH
- KMID: 2285507
- Korean J Physiol Pharmacol.
- 2014 Apr;18(2):169-175.
- doi: 10.4196/kjpp.2014.18.2.169
Human organic cation/carnitine transporter 1 (OCTN1) plays an important role in the transport of drugs and endogenous substances. It is known that a missense variant of OCTN1 is significantly associated... -
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- Functional Haplotype Frequencies of the Interleukin-1B Promoter in the Korean Population
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Lee KA
- KMID: 2166318
- Genomics Inform.
- 2008 Mar;6(1):29-31.
Single nucleotide polymorphisms (SNPs) in the promoter region of the IL-1B (interleukin-1) gene have been implicated in a variety of diseases that have an inflammatory component. However, there has been... -
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- Promoter effects of adeno-associated viral vector for transgene expression in the cochlea in vivo
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Liu Y, Okada T, Nomoto T, Ke X, Kume A, Ozawa K, Xiao S
- KMID: 1094657
- Exp Mol Med.
- 2007 Apr;39(2):170-175.
The aims of this study were to evaluate the expression of enhanced green fluorescent protein (EGFP) driven by 6 different promoters, including cytomegalovirus IE enhancer and chicken beta-actin promoter (CAG),... -
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- Effects of Genotype of Tumor Necrosis Factor Alpha Promoter on Bladder Tumor Grade
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Jeong P, Kim WJ, Kim EJ, Kim JS, Eum MS, Lee SC
- KMID: 2060982
- Korean J Urol.
- 2002 Mar;43(3):224-230.
Purpose: Several polymorphic sites have been reported in the tumor necrosis factor alpha (TNF-alpha) promoter. Comparative studies on TNF-alpha production with promoter genotype have reported variable results, particularly in the... -
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- The role of promoter methylation in Epstein-Barr virus (EBV) microRNA expression in EBV-infected B cell lines
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Kim DN, Song YJ, Lee SK
- KMID: 1015459
- Exp Mol Med.
- 2011 Jul;43(7):401-410.
- doi: 10.3858/emm.2011.43.7.044
Epstein-Barr virus (EBV) microRNAs (miRNAs) are expressed in EBV-associated tumors and cell lines, but the regulation mechanism of their expression is unclear yet. We investigated whether the expression of EBV... -
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- Polymorphism in the promoter region of the plasminogen activator inhibitor-1 (PAI-1) gene in Kawasaki disease
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Han MY
- KMID: 2278489
- Korean J Pediatr.
- 2007 Jun;50(6):570-575.
- doi: 10.3345/kjp.2007.50.6.570
PURPOSE: To demonstrate genetic background of pathogenesis of Kawasaki disease (KD), I examined the genetic polymorphism of plasminogen activator inhibitor-1 (PAI-1) in KD patients. METHODS: PCR-RFLP of PAI- 1 promotor... -
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- IL-10 gene promoter polymorphisms in Korean generalized aggressive periodontitis patients
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Ryn JS, Kim OS
- KMID: 2191723
- J Korean Acad Periodontol.
- 2007 Sep;37(3):563-573.
- doi: 10.5051/jkape.2007.37.3.563
Genetic polymorphisms associated with aggressive periodontitis have previously been reported. Interleukin-10 is an immunoregulatory cyto ine that plays a role in the patho genesis of periodontitis. Individual capacity for IL-10... -
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- Sterol-independent repression of low density lipoprotein receptor promoter by peroxisome proliferator activated receptor gamma coactivator-1alpha (PGC-1alpha)
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Jeong JH, Cho S, Kim Pak Y
- KMID: 756233
- Exp Mol Med.
- 2009 Jun;41(6):406-416.
- doi: 10.3858/emm.2009.41.6.046
Peroxisome proliferator activated receptor (PPAR) gamma coactivator-1alpha (PGC-1alpha) may be implicated in cholesterol metabolism since PGC-1alpha co-activates estrogen receptor alpha (ERalpha) transactivity and estrogen/ERalpha induces the transcription of LDL receptor... -
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- A Novel Rapid Fungal Promoter Analysis System Using the Phosphopantetheinyl Transferase Gene, npgA, in Aspergillus nidulans
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Song HY, Choi D, Han DM, Kim DH, Kim JM
- KMID: 2434572
- Mycobiology.
- 2018 Dec;46(4):429-439.
- doi: 10.1080/12298093.2018.1548806
To develop a convenient promoter analysis system for fungi, a null-pigment mutant (NPG) of Aspergillus nidulans was used with the 4′-phosphopantetheinyl transferase (PPTase) gene, npgA, which restores the normal pigmentation... -
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- Early growth response protein 1 acts as an activator of SOX18 promoter
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Petrovic I, Kovacevic-Grujicic N, Stevanovic M
- KMID: 983986
- Exp Mol Med.
- 2010 Feb;42(2):132-142.
- doi: 10.3858/emm.2010.42.2.015
Sex-determining region Y box 18 (Sox18/SOX18) gene is an important regulator of vascular development playing a role in endothelial cell specification or differentiation, angiogenesis and atherogenesis. The aim of this... -
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- Recombinant AAV Vector with MITF-M Promoter for Melanoma Gene Therapy
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Park SW, Paik SY
- KMID: 1434773
- J Bacteriol Virol.
- 2012 Mar;42(1):57-62.
- doi: 10.4167/jbv.2012.42.1.57
We have developed the recombinant adeno-associated virus (AAV) carrying the EGFP gene under the control of the microphtalmia-associated transcription factor-M (MITF-M) promoter region for melanoma-specific expression. MITF-M distal enhancer (MDE)... -
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- Association of Polymorphisms in the Vitamin D Receptor Promoter with Idiopathic Short Stature
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Choi SK, Park MS, Song JK, Yoon KS, Yoon KL, Shim KS
- KMID: 1793048
- J Korean Med Sci.
- 2013 Sep;28(9):1329-1333.
- doi: 10.3346/jkms.2013.28.9.1329
The genetic alterations of vitamin D receptor (VDR) are related with the growth of long bone. There were a lot of reports regarding an association of polymorphisms in the VDR... -
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- The Use of Pharmacogenomic Method for the Prediction of Antidepressant Responsiveness
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Kim DK, Lim SW
- KMID: 2202793
- J Korean Soc Biol Psychiatry.
- 2002 Jul;9(1):25-33.
Serotonin transporter(5-HTT) is one of the major action site of antidepressants in neuronal cells. According to the recent studies, it is known that the functional polymorphism in the promoter region... -
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- Promoter Methylation in the Genesis of Gastrointestinal Cancer
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Boland CR, Shin SK, Goel A
- KMID: 1758556
- Yonsei Med J.
- 2009 Jun;50(3):309-321.
- doi: 10.3349/ymj.2009.50.3.309
Colorectal cancers (CRC)-and probably all cancers-are caused by alterations in genes. This includes activation of oncogenes and inactivation of tumor suppressor genes (TSGs). There are many ways to achieve these... -
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- Persistent α-Fetoprotein Elevation in Healthy Adults and Mutational Analysis of α-Fetoprotein Promoter, Enhancer, and Silencer Regions
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Jeon Y, Choi YS, Jang ES, Kim JW, Jeong SH
- KMID: 2412165
- Gut Liver.
- 2017 Jan;11(1):136-141.
- doi: 10.5009/gnl16069
BACKGROUND/AIMS: α-Fetoprotein (AFP) is normally 1 year, and 20 controls with low AFP levels ( -
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- Association study between OCTN1 functional haplotypes and Crohn's disease in a Korean population
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Jung ES, Park HJ, Kong KA, Choi JH, Cheon JH
- KMID: 2371063
- Korean J Physiol Pharmacol.
- 2017 Jan;21(1):11-17.
- doi: 10.4196/kjpp.2016.21.1.11
Crohn's disease (CD) is a chronic inflammatory bowel disease with multifactorial causes including environmental and genetic factors. Several studies have demonstrated that the organic cation/carnitine transporter 1 (OCTN1) non-synonymous variant... -
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