- Time Dependent Bladder Apoptosis Induced by Acute Bladder Outlet Obstruction and Subsequent Emptying is Associated with Decreased MnSOD Expression and Bcl-2/Bax Ratio
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Li WJ, Shin MK, Oh SJ
- KMID: 1779237
- J Korean Med Sci.
- 2010 Nov;25(11):1652-1656.
- doi: 10.3346/jkms.2010.25.11.1652
Ischemia/reperfusion (I/R) injury-induced oxidative stress plays an important role in the functional impairment of the bladder following acute bladder outlet obstruction (BOO) via induction of apoptosis. The purpose of this... -
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- The Synergistic Apoptotic Interaction of Indole-3-Carbinol and Genistein with TRAIL on Endometrial Cancer Cells
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Parajuli B, Shin SJ, Kwon SH, Cha SD, Lee HG, Bae I, Cho CH
- KMID: 1786959
- J Korean Med Sci.
- 2013 Apr;28(4):527-533.
- doi: 10.3346/jkms.2013.28.4.527
Induction of apoptosis in target cells is a key mechanism by which chemotherapy promotes cell killing. The purpose of this study was to determine whether Indole-3-Carbinol (I3C) and Genistein in... -
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- Elm tree bark extract inhibits HepG2 hepatic cancer cell growth via pro-apoptotic activity
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Kim TM, Shin SK, Kim TW, Youm SY, Kim DJ, Ahn B
- KMID: 1364997
- J Vet Sci.
- 2012 Mar;13(1):7-13.
- doi: 10.4142/jvs.2012.13.1.7
Control of inflammation is widely accepted as an important strategy for cancer chemoprevention. Anti-inflammatory effects of bark extracts of elm tree (BEE) have been amply reported. Therefore, BEE may be... -
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- IL-1beta Acts in Synergy with Endogenous IL-1beta in A375-S2 Human Melanoma Cell Apoptosis Through Mitochondrial Pathway
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Wang C, Wang MW, Tashiro SI, Onodera S, Ikejima T
- KMID: 1712732
- J Korean Med Sci.
- 2005 Aug;20(4):555-561.
- doi: 10.3346/jkms.2005.20.4.555
Interleukin-1beta (IL-1beta) is a pivotal proinflammatory cytokine. To investigate the mechanism of IL-1beta-induced cell death in human malignant melanoma A375-S2 cells, MTT assay, photomicroscopical observation, DNA agarose gel electrophoresis, radioimmunoassay... -
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- The colchicine derivative CT20126 shows a novel microtubule-modulating activity with apoptosis
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Kim SK, Cho SM, Kim H, Seok H, Kim SO, Kwon TK, Chang JS
- KMID: 2154238
- Exp Mol Med.
- 2013 Apr;45(4):e19.
New colchicine analogs have been synthesized with the aim of developing stronger potential anticancer activities. Among the analogs, CT20126 has been previously reported to show immunosuppressive activities. Here, we report... -
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- Resveratrol protects SH-SY5Y neuroblastoma cells from apoptosis induced by dopamine
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Lee MK, Kang SJ, Poncz M, Song KJ, Park KS
- KMID: 1047089
- Exp Mol Med.
- 2007 Jun;39(3):376-384.
Dopamine (DA) is an oxidant that may contribute to the degeneration of dopaminergic neurons. The present study demonstrates that DA-induced cytotoxicity in human-derived neurotypic cells, SH-SY5Y, is prevented by resveratrol,... -
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- Histamine and spontaneously released mast cell granules ffect the cell growth of human hepatocellular carcinoma cells
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Lampiasi N, Azzolina A, Montalto G, Cervello M
- KMID: 1047079
- Exp Mol Med.
- 2007 Jun;39(3):284-294.
The role of mast cells in tumor growth is still controversial. In this study we analyzed the effects of both histamine and pre-formed mediators spontaneously released by mast cells on... -
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