- Phosphorylation and Reorganization of Keratin Networks: Implications for Carcinogenesis and Epithelial Mesenchymal Transition
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Kim HJ, Choi WJ, Lee CH
- KMID: 2382358
- Biomol Ther.
- 2015 Jul;23(4):301-312.
- doi: 10.4062/biomolther.2015.032
Metastasis is one of hallmarks of cancer and a major cause of cancer death. Combatting metastasis is highly challenging. To overcome these difficulties, researchers have focused on physical properties of... -
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- A serine/threonine phosphatase 1 of Streptococcus suis type 2 is an important virulence factor
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Fang L, Zhou J, Fan P, Yang Y, Shen H, Fang W
- KMID: 2398502
- J Vet Sci.
- 2017 Dec;18(4):439-447.
- doi: 10.4142/jvs.2017.18.4.439
Streptococcus suis is regarded as one of the major pathogens of pigs, and Streptococcus suis type 2 (SS2) is considered a zoonotic bacterium based on its ability to cause meningitis... -
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- Differential gene expression pattern in brains of acrylamide-administered mice
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Han CH
- KMID: 1435820
- Korean J Vet Res.
- 2012 Jun;52(2):99-104.
The present study was performed to evaluate the relationship between the neurotoxicity of acrylamide and the differential gene expression pattern in mice. Both locomotor test and rota-rod test showed that... -
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- The Effects of Cyclosporin A on the Signal Transduction System in the Rat Brain
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Koo YJ, Kang UG, Roh MS, Ahn YM, Park JB, Kim YS
- KMID: 1985333
- Korean J Psychopharmacol.
- 2001 Dec;12(4):294-300.
The most important molecular mechanisms of intraneuronal signal transduction are those mediated by calcium and reversible protein phosphorylation. Although many studies pursued the activation of the protein kinases in the... -
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- Curcumin treatment recovery the decrease of protein phosphatase 2A subunit B induced by focal cerebral ischemia in Sprague-Dawley rats
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Shah FA, Park DJ, Gim SA, Koh PO
- KMID: 2312130
- Lab Anim Res.
- 2015 Sep;31(3):134-138.
- doi: 10.5625/lar.2015.31.3.134
Curcumin provides various biological effects through its anti-inflammatory and antioxidant properties. Moreover, curcumin exerts a neuroprotective effect against ischemic condition-induced brain damage. Protein phosphatase 2A (PP2A) is a ubiquitous serine... -
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- BCL2 antagonist of cell death kinases, phosphatases, and ovarian cancer sensitivity to cisplatin
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Bansal N, Marchion D, Bicaku E, Xiong Y, Chen N, Stickles X, Sawah EA, Wenham RM, Apte SM, Gonzalez-Bosquet J, Judson PL, Hakam A, Lancaster
- KMID: 2177512
- J Gynecol Oncol.
- 2012 Jan;23(1):35-42.
- doi: 10.3802/jgo.2012.23.1.35
OBJECTIVE: The BCL2 family proteins are critical mediators of cellular apoptosis and, as such, have been implicated as determinants of cancer cell chemo-sensitivity. Recently, it has been demonstrated that the... -
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- In Vivo Effects of Adipose-Derived Stem Cells in Inducing Neuronal Regeneration in Sprague-Dawley Rats Undergoing Nerve Defect Bridged with Polycaprolactone Nanotubes
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Kim DY, Choi YS, Kim SE, Lee JH, Kim SM, Kim YJ, Rhie JW, Jun YJ
- KMID: 2151412
- J Korean Med Sci.
- 2014 Nov;29(Suppl 3):S183-S192.
- doi: 10.3346/jkms.2014.29.S3.S183
There have been many attempts for regeneration of peripheral nerve injury. In this study, we examined the in vivo effects of non-differentiated and neuronal differentiated adipose-derived stem cells (ADSCs) in... -
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- Modulated Gene Expression of Toxoplasma gondii Infected Retinal Pigment Epithelial Cell Line (ARPE-19) via PI3K/Akt or mTOR Signal Pathway
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Zhou W, Quan JH, Gao FF, Ismail HA, Lee YH, Cha GH
- KMID: 2412732
- Korean J Parasitol.
- 2018 Apr;56(2):135-145.
- doi: 10.3347/kjp.2018.56.2.135
Due to the critical location and physiological activities of the retinal pigment epithelial (RPE) cell, it is constantly subjected to contact with various infectious agents and inflammatory mediators. However, little... -
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- Transcriptome analyses of chronic traumatic encephalopathy show alterations in protein phosphatase expression associated with tauopathy
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Seo JS, Lee S, Shin JY, Hwang YJ, Cho H, Yoo SK, Kim Y, Lim S, Kim YK, Hwang EM, Kim SH, Kim CH, Hyeon SJ, Yun JY, Kim J, Kim Y, Alvarez VE, Stein TD, Lee J, Kim DJ, Kim JI, Kowall NW, Ryu H, McKee AC
- KMID: 2382695
- Exp Mol Med.
- 2017 May;49(5):e333.
- doi: 10.1038/emm.2017.56
Chronic traumatic encephalopathy (CTE) is a progressive neurodegenerative disorder that is associated with repetitive head injury and has distinctive neuropathological features that differentiate this disease from other neurodegenerative diseases. Intraneuronal... -
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