- Activation of phosphatidylinositol 4, 5-biphosphate(PIP2) cascade by thyroid stimulating antibody
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Chung JH, Cho BY, Jeon JS, Park KS, Kim SY, Lee HK, Koh CS
- KMID: 1686906
- J Korean Soc Endocrinol.
- 1993 Dec;8(4):422-431.
No abstract available. -
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- A Case of Recrrent Spontaneous Abortion Associated with Antiphospholipid Syndrome
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Nam YS, Han SY, Choi DH, Yoon TK, Cha KY
- KMID: 1930523
- Korean J Fertil Steril.
- 1998 Dec;25(3):277-280.
Antiphospholipid antibody is an immunoglobulin which may be of any class and which reacts with any phospholipid. For clinical use the definition of the term anti-phospholipid antibody is usually restricted... -
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- A Study of the Pathway of Nitric Oxide Production by Nitroglycerin in Trabecular Meshwork Cells
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Yoon SH, Kim JW
- KMID: 2338452
- J Korean Ophthalmol Soc.
- 2013 Sep;54(9):1429-1434.
PURPOSE: To investigate the effects of nitroglycerin on the production of nitric oxide and its related pathway in cultured human trabecular meshwork cells (HTMC). METHODS: Primarily cultured HTMC were exposed to... -
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- Lipidomic analysis of plasma lipids composition changes in septic mice
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Ahn WG, Jung JS, Song DK
- KMID: 2414264
- Korean J Physiol Pharmacol.
- 2018 Jul;22(4):399-408.
- doi: 10.4196/kjpp.2018.22.4.399
A lipidomic study on extensive plasma lipids in bacterial peritonitis (cecal ligation and puncture, CLP)-induced sepsis in mice was done at 24 h post-CLP. The effects of administration of lysophosphatidylcholine... -
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- Control of ovarian primordial follicle activation
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Kim JY
- KMID: 2167514
- Clin Exp Reprod Med.
- 2012 Mar;39(1):10-14.
- doi: 10.5653/cerm.2012.39.1.10
The ovarian follicles develop initially from primordial follicles. The majority of ovarian primordial follicles are maintained quiescently as a reserve for the reproductive life span. Only a few of them... -
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- Insulin Resistance and Erectile Dysfunction
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Kim SC
- KMID: 2294085
- Korean J Urol.
- 2006 Sep;47(9):917-927.
- doi: 10.4111/kju.2006.47.9.917
Insulin resistance is a hallmark of metabolic syndrome, including type 2 diabetes mellitus and obesity which are characterized by endothelial dysfunction. The endothelial dysfunction leads to erectile dysfunction (ED). Thus,... -
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- Role of Oxidative Stress in Neurodegenerative Diseases and Ischemic Stroke, and Prospects of Antioxidant Therapies as a New Therapeutic Strategy
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Koh SH, Kim SH
- KMID: 2053699
- Hanyang Med Rev.
- 2006 Feb;26(1):33-43.
Roles of oxidative stress have recently been emphasized in the pathogenic mechanisms of neurodegenerative diseases and ischemic stroke. Many recent increasing evidence support that oxidative stress induces neuronal death related... -
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- The Role of Phosphatase and Tensin Homolog Deleted on Chromosome Ten (PTEN) in Lung Cancer
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Lee HK, Lee YC
- KMID: 2325380
- J Lung Cancer.
- 2004 Mar;3(1):1-5.
Lung cancer remains the primary cause of cancer-related death in the world, and the number of cases continues to increase. Like any other human cancer, the development of lung cancer... -
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- Systemic Treatment for Metastatic Bladder Cancer
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Sym SJ
- KMID: 2268951
- Korean J Med.
- 2015 Nov;89(5):515-521.
- doi: 10.3904/kjm.2015.89.5.515
Metastatic bladder cancer is generally incurable, with a median survival of 14 to 15 months under a modern chemotherapy regimen. Cisplatin-based chemotherapy, including the combination regimens methotrexate-vinblastine-doxorubicin-cisplatin and gemcitabine-cisplatin, are... -
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- PTEN Methylation Dependent Sinonasal Mucosal Melanoma
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Lee SH, Roh MR, Kang B, Park KH, Kim SH, Lee SE, Rha SY
- KMID: 2454366
- Cancer Res Treat.
- 2016 Apr;48(2):853-858.
- doi: 10.4143/crt.2014.356
Sinonasal mucosal melanoma (SMM) is an aggressive and rare type of melanoma. Although the classic RAS-RAF-MEK pathway is thought to be the main pathway involved in melanoma pathogenesis, genetic alterations... -
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- Signature Genes in Macrodactyly through Transcriptome Network Analysis Reveal their Association of Lipid Metabolism
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Choi JW, Lee HJ, Oh JW
- KMID: 2392273
- Korean J Phys Anthropol.
- 2017 Sep;30(3):77-85.
- doi: 10.11637/kjpa.2017.30.3.77
Macrodactyly is one of the most difficult hand anomalies to treat not only surgically but medically as well. Little is known about the molecular pathways and lipid metabolism of this... -
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- Effects of Recombinant EPO on Death of Cortical Neuron in Chronic Hypoxia
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Kim HJ, Baek JG, Yang JS, Kang KY, Kim KR, Kim H
- KMID: 1598729
- Korean J Phys Anthropol.
- 2005 Dec;18(4):291-301.
Chronic hypoxia has been associated with change in neurovascular behavior, mediated, in part, by erythropoietin (EPO). EPO, a hematopoietic growth factor, could act as a neurotrophic factor. In the present... -
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- Regulation of Adenosine-activated GIRK Channels by Gq-coupled Receptors in Mouse Atrial Myocytes
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Cho H
- KMID: 2285395
- Korean J Physiol Pharmacol.
- 2010 Jun;14(3):145-150.
- doi: 10.4196/kjpp.2010.14.3.145
Adenosine (Ado) is an important mediator of the endogenous defense against ischemia-induced injury in the heart. The action of Ado is mediated by activation of G protein-gated inwardly rectifying K+... -
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- Molecular Diagnosis for Personalized Target Therapy in Gastric Cancer
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Cho JY
- KMID: 2372461
- J Gastric Cancer.
- 2013 Sep;13(3):129-135.
Gastric cancer is the second leading cause of cancer-related deaths worldwide. In advanced and metastatic gastric cancer, the conventional chemotherapy with limited efficacy shows an overall survival period of about... -
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- Modulation of Large Conductance Ca2+-activated K+ Channel of Skin Fibroblast (CRL-1474) by Cyclic Nucleotides
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Yun J, Kim S, Bang H
- KMID: 2285320
- Korean J Physiol Pharmacol.
- 2005 Apr;9(2):131-135.
Potassium channels in human skin fibroblast have been studied as a possible site of Alzheimer disease pathogenesis. Fibroblasts in Alzheimer disease show alterations in signal transduction pathway such as changes... -
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- Mass spectrometry based cellular phosphoinositides profiling and phospholipid analysis: A brief review
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Kim Y, Shanta SR, Zhou LH, Kim KP
- KMID: 946664
- Exp Mol Med.
- 2010 Jan;42(1):1-11.
- doi: 10.3858/emm.2010.42.1.001
Phospholipids are key components of cellular membrane and signaling. Among cellular phospholipids, phosphoinositides, phosphorylated derivatives of phosphatidylinositol are important as a participant in essential metabolic processes in animals. However, due... -
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- Characterization and Differentiation of Circulating Blood Mesenchymal Stem Cells and the Role of Phosphatidylinositol 3-Kinase in Modulating the Adhesion
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Park YK, Heo SJ, Koak JY, Park GS, Cho TJ, Kim SK, Cho J
- KMID: 2465897
- Int J Stem Cells.
- 2019 Jul;12(2):265-278.
- doi: 10.15283/ijsc18136
Bone marrow mesenchymal stem cells (BM MSCs) can differentiate into multi-lineage tissues. However, obtaining BM MSCs by aspiration is difficult and can be painful; therefore peripheral blood (PB) MSCs might... -
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- The role of G protein in the activation of phospholipase C from bovine brain
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Kim JH, Lee DJ, Byun YJ
- KMID: 2377584
- Yeungnam Univ J Med.
- 1992 Dec;9(2):288-301.
- doi: 10.12701/yujm.1992.9.2.288
The objective of the present study was to identify the characteristics of phospholipase C (PLC) isozymes purified from bovine brain and to investigate their interrelationship with G protein. The purified PLC... -
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- The Role of Nuclear Factor kB and Phosphatidylinositol 3 - kinase in Trypsinogen Activation in Cerulein - Stimulated Rat Pancreatic Acini
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Kim YJ, Kim YT, Hwang JH, Kim J, Jeong JB, Yoon YB, Kim CY
- KMID: 2085005
- Korean J Gastroenterol.
- 2001 Dec;38(6):427-432.
BACKGROUND/AIMS: Intra-acinar cell activation of trypsinogen is a critical event in cerulein-induced pancreatitis. However, little is known about the intracellular signal transduction systems involved in trypsinogen activation. This study focused... -
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- Changes in Profiles of Humoral Immune Facrors after Treatment of Gonadotropin Releasing Hormone Agonist in Patients with Endometriosis
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Kim JG, Moon SY, Kang SB, Lee JY, Kim DH, Choi DS, Kim DW
- KMID: 2235717
- Korean J Fertil Steril.
- 2000 Mar;27(1):83-90.
OBJECTIVES: To investigate the incidence of antiphospholipid antibodies in patients with proven endometriosis and apparently normal controls, and to evaluate the changes in profiles of humoral immune factors in endometriosis... -
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