- Effects of Curcumin and Genistein on Phorbol Ester or Tumor Necrosis Factor-alpha-Induced Mucin Production from Human Airway Epithelial Cells
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Lee SY, Lee HJ, Lee JW, Jeon BK, Kim JO, Lee CJ
- KMID: 1442851
- Tuberc Respir Dis.
- 2011 Mar;70(3):218-223.
- doi: 10.4046/trd.2011.70.3.218
BACKGROUND: We investigated whether curcumin and genistein affect the MUC5AC mucin production from human airway epithelial cells that is induced by phorbol 12-myristate 13-acetate (PMA) or tumor necrosis factor-alpha (TNF-alpha). METHODS:... -
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- Interleukin-8 production and interleukin-8 mRNA expression induced by lipopolysaccharides from Prevotella intermedia and Prevotella nigrescens in monocyte-derived macrophages
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Kim SJ
- KMID: 1733735
- J Korean Acad Periodontol.
- 2009 Jun;39(2):177-184.
- doi: 10.5051/jkape.2009.39.2.177
PURPOSE: Interleukin-8 (IL-8) is an important mediator of immune and inflammatory reactions and is produced by a variety of different cell types. This study was undertaken to investigate the effects... -
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- Effect of Apocynin on Acute Lung Injury in Rats Given Interleukin-1alpha Intratracheally
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Lee YM
- KMID: 2319532
- Tuberc Respir Dis.
- 2011 Jun;70(6):482-489.
BACKGROUND: Based on the assertion that apocynin diminishes acute lung injury (ALI) by inhibition of NADPH oxidase, the effect of apocynin was tested in interleukin-1alpha (IL-1)-induced ALI in rats. METHODS: IL-1... -
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- The Inhibitory Effect of Eupatilin on the Agonist-Induced Regulation of Vascular Contractility
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Je HD, Kim HD, Jeong JH
- KMID: 1432760
- Korean J Physiol Pharmacol.
- 2013 Feb;17(1):31-36.
- doi: 10.4196/kjpp.2013.17.1.31
The present study was undertaken to investigate the influence of eupatilin on vascular smooth muscle contractility and to determine the mechanism involved. Denuded aortic rings from male rats were used... -
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- Leptin potentiates Prevotella intermedia lipopolysaccharide-induced production of TNF-alpha in monocyte-derived macrophages
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Kim SJ
- KMID: 2212138
- J Periodontal Implant Sci.
- 2010 Jun;40(3):119-124.
- doi: 10.5051/jpis.2010.40.3.119
PURPOSE: In addition to regulating body weight, leptin is also recognized for its role in the regulation of immune function and inflammation. The purpose of this study was to investigate... -
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- NFATc1 and NFATc3 is Involved in the Expression of Receptor Activator of NF-kappaB Ligand in Activated T Lymphocytes
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Heo SJ, Park HJ, Baek JH
- KMID: 1431127
- Int J Oral Biol.
- 2013 Mar;38(1):37-42.
Receptor activator of NF-kappaB ligand (RANKL) is an essential cytokine for osteoclast differentiation, activation and survival. T lymphocytes such as T17 cells, a subset of T helper cells that produce... -
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- Effect of Chrysin on Gene Expression and Production of MUC5AC Mucin from Cultured Airway Epithelial Cells
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Shin HD, Lee HJ, Sikder MA, Park SH, Ryu J, Hong JH, Kim JO, Seok JH, Lee CJ
- KMID: 2320194
- Tuberc Respir Dis.
- 2012 Oct;73(4):204-209.
BACKGROUND: We investigated whether chrysin affected MUC5AC mucin production and gene expression induced by phorbol ester (phorbol 12-myristate 13-acetate, PMA) or epidermal growth factor (EGF) from human airway epithelial cells. METHODS:... -
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- Chemokine Lkn-1/CCL15 enhances matrix metalloproteinase-9 release from human macrophages and macrophage-derived foam cells
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Kwon SH, Ju SA, Kang JH, Kim CS, Yoo HM, Yu R
- KMID: 2313362
- Nutr Res Pract.
- 2008 Jun;2(2):134-137.
Atherosclerosis is characterized by a chronic inflammatory disease, and chemokines play an important role in both initiation and progression of atherosclerosis development. Leukotactin-1 (Lkn-1/CCL15), a new member of the human... -
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- The Effect of Doxycycline on PMA-Induced MUC5B Expression via MMP-9 and p38 in NCI-H292 Cells
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Bae CH, Chen SM, Lee HM, Song SY, Kim YD
- KMID: 2166398
- Clin Exp Otorhinolaryngol.
- 2011 Dec;4(4):177-183.
OBJECTIVES: Doxycycline is commonly used in medicine for its bacteriostatic antimicrobial properties. Recent studies have reported that doxycycline also has anti-inflammatory effects. Matrix metalloproteinase (MMP)-9 has been found to be... -
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- The Relaxing Effect of alpha-Defensin 1 on the Adrenergic Responses of Rat Bladder
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Lee SY, Kim DK, Kim KD, Myung SC, Lee MY
- KMID: 1448917
- Korean J Physiol Pharmacol.
- 2011 Jun;15(3):143-147.
- doi: 10.4196/kjpp.2011.15.3.143
Defensins, cysteine-rich cationic polypeptides released from neutrophils, are known to have powerful antimicrobial properties. In this study, we sacrificed 30 rats to investigate the effects of alpha-defensin 1 on detrusor... -
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- Effects of Polychlorinated Biphenyls on the Development of Neuronal Cells in Growth Period; Structure-Activity Relationship
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Do Y, Lee DK
- KMID: 2165388
- Exp Neurobiol.
- 2012 Mar;21(1):30-36.
- doi: 10.5607/en.2012.21.1.30
Polychlorinated biphenyls (PCBs) are accumulated in our body through food chain and cause a variety of adverse health effects including neurotoxicities such as cognitive deficits and motor dysfunction. In particular,... -
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- Chlorination of ortho-position on Polychlorinated Biphenyls Increases Protein Kinase C Activity in Neuronal Cells
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Lee YJ, Yang JH
- KMID: 1432247
- Toxicol Res.
- 2012 Jun;28(2):107-112.
Polychlorinated biphenyls (PCBs) are persistent and bioaccumulative environmental pollutants. Recently, it is suggested that neurotoxic effects such as motor dysfunction and impairment in memory and learning have been associated with... -
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- Effect of Epigallocatechin-3-Gallate on PMA-Induced MUC5B Expression in Human Airway Epithelial Cells
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Song EJ, Bae CH, Kim JY, Kim YW, Park SY, Song SY, Kim YD
- KMID: 2278432
- Clin Exp Otorhinolaryngol.
- 2013 Dec;6(4):237-242.
OBJECTIVES: Among the inflammatory mediators, phorbol 12-myristate 13-acetate (PMA) is associated with the regulation of MUC5B expression in the airway epithelial cells. Epigallocatechin-3-gallate (EGCG) is the major component of green... -
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- Functional Expression of TRPV4 Cation Channels in Human Mast Cell Line (HMC-1)
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Kim KS, Shin DH, Nam JH, Park KS, Zhang YH, Kim WK, Kim SJ
- KMID: 2071715
- Korean J Physiol Pharmacol.
- 2010 Dec;14(6):419-425.
- doi: 10.4196/kjpp.2010.14.6.419
Mast cells are activated by specific allergens and also by various nonspecific stimuli, which might induce physical urticaria. This study investigated the functional expression of temperature sensitive transient receptor potential... -
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- Phorbol 12-Myristate 13-Acetate Induces MUC16 Expression via PKCdelta and p38 in Human Airway Epithelial Cells
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Bae CH, Kim HS, Song SY, Kim YD
- KMID: 2134600
- Clin Exp Otorhinolaryngol.
- 2012 Sep;5(3):161-169.
- doi: 10.3342/ceo.2012.5.3.161
OBJECTIVES: Phorbol 12-myristate 13-acetate (PMA) is widely used as a protein kinase C (PKC) activator, PKC is involved in the secretion of mucins. MUC16, one of the membrane-bound mucins, is... -
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- Phorbol 12-Myristate 13-Acetate Enhances Long-Term Potentiation in the Hippocampus through Activation of Protein Kinase Cdelta and epsilon
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Kim EC, Lee MJ, Shin SY, Seol GH, Han SH, Yee J, Kim C, Min SS
- KMID: 1432763
- Korean J Physiol Pharmacol.
- 2013 Feb;17(1):51-56.
- doi: 10.4196/kjpp.2013.17.1.51
Many intracellular proteins and signaling cascades contribute to the sensitivity of N-methyl-D-aspartate receptors (NMDARs). One such putative contributor is the serine/threonine kinase, protein kinase C (PKC). Activation of PKC by... -
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- Blockade of vascular angiogenesis by Aspergillus usamii var. shirousamii-transformed Angelicae Gigantis Radix and Zizyphus jujuba
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Kang SW, Choi JS, Bae JY, Li J, Kim DS, Kim JL, Shin SY, You HJ, Park HS, Ji GE, Kang YH
- KMID: 2313370
- Nutr Res Pract.
- 2009 Mar;3(1):3-8.
The matrix metalloproteinases (MMP) play an important role in tumor invasion, angiogenesis and inflammatory tissue destruction. Increased expression of MMP was observed in benign tissue hyperplasia and in atherosclerotic lesions.... -
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