- Clinical Significance of Microsatellite Instability in Sporadic Epithelial Ovarian Tumors
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Yoon BS, Kim YT, Kim JH, Kim SW, Nam EJ, Cho NH, Kim JW, Kim S
- KMID: 1084501
- Yonsei Med J.
- 2008 Apr;49(2):272-278.
- doi: 10.3349/ymj.2008.49.2.272
PURPOSE: We evaluated the expression of microsatellite instability (MSI) in sporadic ovarian tumors using 5 standard and 9 new MSI markers to determine the clinical significance of MSI in sporadic... -
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- Conditional knockout of brca1/2 and p53 in mouse ovarian surface epithelium: Do they play a role in ovarian carcinogenesis?
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Kim KY, Park DW, Jeung EB, Choi KC
- KMID: 1072177
- J Vet Sci.
- 2010 Dec;11(4):291-297.
- doi: 10.4142/jvs.2010.11.4.291
Alterations of genes are known to be critical for the induction of tumorigenesis, but the mechanism of ovarian carcinogenesis is little understood and remains to be elucidated. In this study,... -
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- Position statements on genetic test for peritoneal, ovarian, and fallopian tubal cancers: Korean Society of Gynecologic Oncology (KSGO)
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Choi MC, Lim MC, Suh DH, Song YJ, Kim TJ, Chang SJ, Kim JW, Korean Society of Gynecologic Oncology
- KMID: 2374238
- J Gynecol Oncol.
- 2016 Jul;27(4):e36.
- doi: 10.3802/jgo.2016.27.e36
No abstract available. -
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- Completeness of pedigree and family cancer history for ovarian cancer patients
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Son Y, Lim MC, Seo SS, Kang S, Park SY
- KMID: 2130124
- J Gynecol Oncol.
- 2014 Oct;25(4):342-348.
- doi: 10.3802/jgo.2014.25.4.342
OBJECTIVE: To investigate the completeness of pedigree and of number of pedigree analysis to know the acceptable familial history in Korean women with ovarian cancer. METHODS: Interview was conducted in 50... -
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- Germline and somatic mutations in homologous recombination genes among Chinese ovarian cancer patients detected using next-generation sequencing
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Zhao Q, Yang J, Li L, Cao D, Yu M, Shen K, the BGI Group
- KMID: 2413427
- J Gynecol Oncol.
- 2017 Jul;28(4):e39.
- doi: 10.3802/jgo.2017.28.e39
OBJECTIVE: To define genetic profiling of homologous recombination (HR) deficiency in Chinese ovarian cancer patients. METHODS: we have applied next-generation sequencing to detect deleterious mutations through all exons in 31 core... -
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- Young Israeli women with epithelial ovarian cancer: prevalence of BRCA mutations and clinical correlates
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Helpman L, Zidan O, Friedman E, Kalfon S, Perri T, Ben-Baruch G, Korach J
- KMID: 2413221
- J Gynecol Oncol.
- 2017 Sep;28(5):e61.
- doi: 10.3802/jgo.2017.28.e61
OBJECTIVE: The current study investigates disease patterns and outcomes in young Israeli epithelial ovarian cancer (EOC) patients and their association with BRCA mutation status. METHODS: Consecutive EOC patients diagnosed at or... -
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- Mutational Analysis of KRAS, BRAF, and TP53 Genes of Ovarian Serous Carcinomas in Korean Women
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Cho YH, Kim DY, Kim JH, Kim YM, Kim KR, Nam JH, Kim YT
- KMID: 2396071
- Yonsei Med J.
- 2009 Apr;50(2):266-272.
PURPOSE: To assess the prevalence of KRAS, BRAF, and TP53 mutations in cases of low-grade and high-grade serous carcinomas and to evaluate the clinical outcomes of these morphologically distinct carcinomas.... -
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- Estimation of Prognostic Marker Genes by Public Microarray Data in Patients with Ovarian Serous Cystadenocarcinoma
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Yang SD, Jang SS, Han JA, Park HS, Kim JI
- KMID: 2374117
- Yonsei Med J.
- 2016 Jul;57(4):872-878.
- doi: 10.3349/ymj.2016.57.4.872
PURPOSE: Lymphatic invasion (LI) is regarded as a predictor of the aggressiveness of ovarian cancer (OC). However, LI is not always the major determinant of long-term patient survival. To establish... -
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- Pathologic findings at risk-reducing salpingo-oophorectomy (RRSO) in germline BRCA mutation carriers with breast cancer: significance of bilateral RRSO at the optimal age in germline BRCA mutation carriers
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Lee YJ, Lee SW, Kim KR, Jung KH, Lee JW, Kim YM
- KMID: 2413850
- J Gynecol Oncol.
- 2017 Jan;28(1):e3.
- doi: 10.3802/jgo.2017.28.e3
OBJECTIVE: Most BRCA1/2 carriers do not undergo risk-reducing salpingo-oophorectomy (RRSO) by the recommended age. This study aimed to find the incidence of precursor lesions and cancer after RRSO. METHODS: We retrospectively... -
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- The NER-related gene GTF2H5 predicts survival in high-grade serous ovarian cancer patients
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Gayarre J, Kamieniak , Cazorla-Jimenez A, Munoz-Repeto I, Borrego S, Garcia-Donas J, Hernando S, Robles-Diaz L, Garcia-Bueno JM, Ramon y Cajal T, Hernandez-Agudo E, Heredia Soto V, Marquez-Rodas I, Echarri MJ, Lacambra-Calvet C, Saez R, Cusido M, Redondo A, Paz-Ares L, Hardisson , Mendiola M, Palacios J, Benitez J, Garcia MJ
- KMID: 2360237
- J Gynecol Oncol.
- 2016 Jan;27(1):e7.
- doi: 10.3802/jgo.2016.27.e7
OBJECTIVE: We aimed to evaluate the prognostic and predictive value of the nucleotide excision repair-related gene GTF2H5, which is localized at the 6q24.2-26 deletion previously reported by our group to... -
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