- Effect of Suvorexant on Nocturnal Delirium in Elderly Patients with Alzheimer's Disease: A Case-series Study
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Hanazawa T, Kamijo Y
- KMID: 2464723
- Clin Psychopharmacol Neurosci.
- 2019 Nov;17(4):547-550.
- doi: 10.9758/cpn.2019.17.4.547
Suvorexant, an orexin receptor antagonist used for insomnia, has been shown to have a preventive effect on delirium in a randomized placebo-controlled trial. However, its effectiveness in the management of... -
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- Recent Updates on Narcolepsy and Hypersomnia
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Hong S
- KMID: 2471262
- J Korean Neuropsychiatr Assoc.
- 2020 Feb;59(1):25-28.
- doi: 10.4306/jknpa.2020.59.1.25
Narcolepsy is a chronic neurological sleep disorder caused by hypocretin neuron loss, resulting in excessive daytime sleepiness, disturbed nocturnal sleep, and intrusions of aspects of rapid eye movement sleep in... -
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- Orexin-A inhibits capsaicin-induced changes in cyclooxygenase-2 and brain-derived neurotrophic factor expression in trigeminal nucleus caudalis of rats
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Kooshki R, Abbasnejad M, Esmaeili Mahani S, Raoof M, Moeini Aghtaei MM, Dabiri S
- KMID: 2417955
- Korean J Pain.
- 2018 Jul;31(3):174-182.
- doi: 10.3344/kjp.2018.31.3.174
BACKGROUND: The trigeminal nucleus caudalis (Vc) is a primary central site for trigeminal transmitting. Noxious stimulation of the trigeminal nociceptors alters the central synaptic releases and neural expression of some... -
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- Narcolepsy in Children
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Seo WS
- KMID: 2317500
- Sleep Med Psychophysiol.
- 2011 Jun;18(1):17-22.
Childhood narcolepsy is one of the underdiagnosed diseases even the first symptoms often appear in childhood. Making diagnosis through history taking is not always easy because the symptoms of childhood... -
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- Narcolepsy: Clinical Feature, Diagnosis and Treatment
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Shin HB
- KMID: 2317492
- Sleep Med Psychophysiol.
- 2010 Dec;17(2):63-68.
Narcolepsy is a central neurologic system disease. It begins early in life with disabling symptoms including excessive daytime sleepiness, cataplexy, sleep paralysis, hypnagogic hallucination and nocturnal sleep fragmentation. Patient with... -
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- Late-Onset Narcolepsy with Cataplexy Unresponsive to Intravenous High-Dose Immunoglobulin Treatment
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Cho JW, Jung NY, Bae JW, Kim DJ, Lee JH, Kanbayashi T
- KMID: 2343436
- J Korean Neurol Assoc.
- 2012 Feb;30(1):57-59.
Narcolepsy with cataplexy (NC) is associated with hypocretin deficiency, and is thought to be an autoimmunity condition. The mean age at onset is estimated to be in the early 20s.... -
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- The Effect of Sleep Loss on Energy and Metabolism
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Kang SG
- KMID: 2317512
- Sleep Med Psychophysiol.
- 2012 Jun;19(1):5-10.
The release of hormones and the metabolism of human body are controlled by the circadian rhythm related to sleep-wake cycle. Growth hormone, prolactin, thyroid stimulating hormone, cortisol, glucose, and insulin-secretion... -
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- Involvement of Heme Oxygenase-1 in Orexin-A-induced Angiogenesis in Vascular Endothelial Cells
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Kim MK, Park HJ, Kim SR, Choi YK, Bae SK, Bae MK
- KMID: 2285575
- Korean J Physiol Pharmacol.
- 2015 Jul;19(4):327-334.
- doi: 10.4196/kjpp.2015.19.4.327
The cytoprotective enzyme heme oxygenase-1 (HO-1) influences endothelial cell survival, proliferation, inflammatory response, and angiogenesis in response to various angiogenic stimuli. In this study, we investigate the involvement of HO-1... -
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- How Leptin Controls the Drive to Eat
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Patterson , Myers MG
- KMID: 2271158
- Korean J Obes.
- 2015 Jun;24(2):69-77.
A complex set of brain based systems modulate feeding to maintain constant body weight. The adipose derived-hormone, leptin, plays a crucial role in this control by acting on diverse leptin... -
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- CDH13 and HCRTR2 May Be Associated with Hypersomnia Symptom of Bipolar Depression: A Genome-Wide Functional Enrichment Pathway Analysis
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Cho CH, Lee HJ, Woo HG, Choi JH, Greenwood , Kelsoe JR
- KMID: 2316503
- Psychiatry Investig.
- 2015 Jul;12(3):402-407.
- doi: 10.4306/pi.2015.12.3.402
Although bipolar disorder is highly heritable, the identification of specific genetic variations is limited because of the complex traits underlying the disorder. We performed a genome-wide association study of bipolar... -
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- Abnormal Cerebral Glucose Metabolism in Patients with Narcolepsy
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Joo EY, Tae WS, Kim JH, Han SJ, Cho YW, Kim L, Yun CH, Kim MH, Kim BT, Hong SB
- KMID: 2343082
- J Korean Neurol Assoc.
- 2004 Aug;22(4):340-344.
BACKGROUND: The purpose of this study was to investigate the differences of cerebral glucose metabolism between narcoleptic patients and normal controls. METHODS: We enrolled 24 patients with narcolepsy who underwent... -
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- Comparison of Narcolepsy with Cataplexy and without Cataplexy: Clinical Variables, HLA-DQB1*0602, and Hypocretin
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Jeong JH, Hong SC, Shin YK, Han JH, Lee SP
- KMID: 2341266
- J Korean Neuropsychiatr Assoc.
- 2007 Jan;46(1):50-57.
OBJECTIVES: Narcolepsy is a sleep disorder, characterized by excessive daytime sleepiness, cataplexy, sleep paralysis and hypnagogic hallucination. Among these symptoms, cataplexy is one of the most pathognomonic symptoms in narcolepsy.... -
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- Excessive Daytime Sleepiness Case Confounding with Thyrotoxicosis
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Chung JK, Kim EJ
- KMID: 2317504
- Sleep Med Psychophysiol.
- 2011 Jun;18(1):40-44.
Narcolepsy is a sleep disorder, which is characterized by excessive daytime sleepiness (EDS) that is typically associated with cataplexy, sleep fragmentation and other REM sleep-related phenomenon such as sleep paralysis... -
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