- Comparison of Gene Expression from Supernumerary Dental Pulp and Periodontal Ligament Stem Cells
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Lee S, Kim J, Kim J
- KMID: 2430483
- J Korean Acad Pediatr Dent.
- 2018 May;45(2):242-249.
- doi: 10.5933/JKAPD.2018.45.2.242
The purpose of this study is to compare the properties of dental pulp and periodontal ligament stem cells from extracted supernumerary teeth by quantitative real-time PCR. Impacted supernumerary teeth in the... -
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- Osteocalcin Expression and Mineralization in Developing Tooth of Xenopus laevis
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Park JH, Kwon KT, Park BK, Lee YH
- KMID: 1789363
- Int J Oral Biol.
- 2015 Mar;40(1):1-9.
- doi: 10.11620/IJOB.2015.40.1.001
Osteocalcin (OC) is the most abundant noncollagenous protein of extracellular matrix in the bone. In an OC deficient mouse, bone formation rates are increased in cancellous and cortical bones. OC... -
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- Role of OD314 During Odontoblast Differentiation
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Park JC, Kim IH, Kim HJ, Jeong MJ, Oh HJ, Jeong JO, Son HH
- KMID: 2283208
- Korean J Phys Anthropol.
- 2005 Sep;18(3):187-196.
Odontoblasts are responsible for the formation and maintenance of dentin which is a mineralized part in dentin-pulp complex of tooth. OD314 was obtained by subtractive hybridization between odontoblasts and osteoblast/dental... -
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- Effect of irradiation on the dental pulp tissues in streptozotocin-induced diabetic rats
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Kang HD, Hwang EH, Lee SR
- KMID: 1887558
- Korean J Oral Maxillofac Radiol.
- 2005 Mar;35(1):9-14.
PURPOSE: To observe the histopathological changes in the pulp tissues of mandibular molars in streptozotocininduced diabetic rats after irradiation. MATERIALS AND METHODS: The male Sprague-Dawley rats weighing approximately 250 gm... -
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- Effect of NFI-C on the Expression of Smad and TGF-betaR1
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Yoon SH, Lee DS, Kim HJ, Lee KY, Yang JH, Kim JW, Kim KT, Park JC
- KMID: 2092897
- Korean J Anat.
- 2007 Jun;40(2):127-135.
NFI-C null mice demonstrate aberrant odontoblast differentiation and abnormal dentin formation, and thus develop molars lacking roots. However, other tissues and organs in the body including ameloblasts appear to be... -
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- MMP-2 and MMP-9 are Differentially Involved in Molar Growth
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Kim MS, Kang JH, Kim DH, Yoo HI, Jung NR, Yang SY, Lee EJ, Kim SH
- KMID: 1445161
- Int J Oral Biol.
- 2011 Dec;36(4):195-201.
Matrix metalloproteinases (MMPs) have been implicated in tissue development and re-modeling. Dynamic morphological changes of tooth germs reflect involvement of these enzymes during odontogenesis. The present study was performed to... -
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- Requirement of Smad4-mediated signaling in odontoblast differentiation and dentin matrix formation
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Yun CY, Choi H, You YJ, Yang JY, Baek JA, Cho ES
- KMID: 2353345
- Anat Cell Biol.
- 2016 Sep;49(3):199-205.
- doi: 10.5115/acb.2016.49.3.199
Dentin is the major part of tooth and formed by odontoblasts. Under the influence of the inner enamel epithelium, odontoblasts differentiate from ectomesenchymal cells of the dental papilla and secrete... -
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- A Trial of Screening of Genes Involved in Odontoblasts Differentiation from Human Dental Pulp Stem Cells
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Park YK, Kim HJ
- KMID: 1431130
- Int J Oral Biol.
- 2012 Dec;37(4):167-173.
This study investigated the genes involved in the differentiation of odontoblasts derived from human dental pulp stem cells (hDPSCs). hDPSCs isolated from human tooth pulp were validated by fluorescence activated... -
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- Inactivation of the OD314 Gene by RNA Interference in Preodontoblast Cell Lines
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Kim HJ, Jeong MJ, Son HH, Park JC
- KMID: 2283179
- Korean J Phys Anthropol.
- 2004 Jun;17(2):121-129.
Tooth development depends on reciprocal interactions between oral epithelium and ectomesenchyme. The ectomesenchyme-derived odontoblasts secrete several collagenous and non-collagenous proteins to form a unique extracellular matrix. OD314 was obtained by... -
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- The Effects of Irradiation and Calcium-deficient Diet on the Expression of Bone Morphogenetic Protein-2/4 during Early Tooth Development
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Park DH, Hwang EH, Lee SR
- KMID: 1924087
- Korean J Oral Maxillofac Radiol.
- 2000 Sep;30(3):169-181.
PURPOSE: To investigate the expression of bone morphogenetic protein(BMP)-2/4 during eary tooth development after irradiation and calcium-deficient diet. MATERIALS AND METHODS: The pregnant three-week-old Sprague-Dawley rats were used for the... -
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- Epidermal Growth Factor Receptor and Nerve Growth Factor Receptor in the Rat Mandibular Molar and Incisor after Submandibular Sialadenectomy
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Choi HG, Kim JG, Cho ES
- KMID: 2092703
- Korean J Anat.
- 1999 Oct;32(5):697-707.
Immunohistochemical changes of epidermal growth factor receptor (EGFR) and nerve growth factor receptor (NGFR) were investigated in the rat mandibular molar and incisors after submandibular sialadenectomy. In the sham operated... -
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- Effect of Metformin on Cell Growth and Differentiation in Cultured Odontoblasts
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Oh CY, Kim SG, Go DS, Yu SK, Kim TH, Kim CS, Park JC, Kim DK
- KMID: 2385804
- Int J Oral Biol.
- 2017 Jun;42(2):39-45.
- doi: 10.11620/IJOB.2017.42.2.039
Metformin (1,1-dimethylbiguanide hydrochloride), derived from French lilac (Galega officinalis), is a first-line anti-diabetic drug prescribed for patients with type 2 diabetes. However, the role of metformin in odontoblastic cell differentiation... -
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- Update on dentin hypersensitivity: with the focus on hydrodynamic theory and mechanosensitive ion channels
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Won J, Oh SB
- KMID: 2460801
- Int J Oral Biol.
- 2019 Sep;44(3):71-76.
- doi: 10.11620/IJOB.2019.44.3.71
Dentin hypersensitivity is an abrupt intense pain caused by innocuous stimuli to exposed dentinal tubules. Mechanosensitive ion channels have been assessed in dental primary afferent neurons and odontoblasts to explain... -
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- Effects of Indomethacin on the physiologic root resorption of deciduous teeth in dogs
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Shin KS, Kang YG, Lee KS
- KMID: 2074789
- Korean J Orthod.
- 2005 Apr;35(2):106-115.
This study was aimed to investigate the effects of indomethacin on physiologic root resorption and to examine the dental pulp and tissue changes around the resorbing teeth. 13-14 week old... -
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- Interaction between odontoblast and bio-calcium phosphate cement reinforced with chitosan
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Chun BD, Kim SW, Lee ST, Kim TH, Lee JH, Kim GC, Kim YD, Kim UK
- KMID: 2328616
- J Korean Assoc Oral Maxillofac Surg.
- 2011 Oct;37(5):415-420.
PURPOSE: Calcium phosphate cement (CPC) is one of many useful materials for restoring tooth defects, periodontium and maxillofacial area. Chitosan is a biodegradable material that has been shown to promote... -
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- Expression and functional characterization of odontoblast-derived gene: OD314
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Kim DH, Kim HJ, Jeong MJ, Son HH, Park JC
- KMID: 2175634
- J Korean Acad Conserv Dent.
- 2004 Jul;29(4):399-408.
- doi: 10.5395/JKACD.2004.29.4.399
Odontoblasts are responsible for the formation and maintenance of dentin. They are known to synthesize unique gene products including dentin sialophosphoprotein (DSPP). Another unique genes of the cells remain unclear. OD314... -
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- Effect of Resveratrol on Cell Differentiation and Mineralization in Cultured Odontoblasts
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Shin SH, Kim JS, Kim SG, Go DS, Yu SK, Kim CS, Park JC, Kim DK
- KMID: 2437350
- Int J Oral Biol.
- 2018 Sep;43(3):133-140.
- doi: 10.11620/IJOB.2018.43.3.133
Resveratrol (3,4′,5,-trihydroxystilbene), a phytoalexin present in grapes, exerts a variety of actions to reduce superoxides, prevents diabetes mellitus, and inhibits inflammation. Resveratrol acts as a chemo-preventive agent and induces apoptotic... -
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- The expression of osteonectin and osteocalcin in the experimental tooth movement in rat
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Bae SR, Kim SC
- KMID: 2271800
- Korean J Orthod.
- 1998 Oct;28(5):699-716.
This study was designed to evaluate the expression of non-collagenous protein in periodontal tissue during the experimental movement of rat incisors, by LSAB(labelled streptavidine biotin) mmunohistochemical staining for osteonectin and... -
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- Col1a1-cre mediated activation of beta-catenin leads to aberrant dento-alveolar complex formation
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Kim TH, Bae CH, Jang EH, Yoon CY, Bae Y, Ko SO, Taketo MM, Cho ES
- KMID: 2046747
- Anat Cell Biol.
- 2012 Sep;45(3):193-202.
- doi: 10.5115/acb.2012.45.3.193
Wnt/beta-catenin signaling plays a critical role in bone formation and regeneration. Dentin and cementum share many similarities with bone in their biochemical compositions and biomechanical properties. Whether Wnt/beta-catenin signaling is... -
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- Thioredoxin Peroxidases are Differentially Expressed in Developing Tooth Germs in Rats
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Kim HJ, Kang JH, Jeon SK, Jung SW, Kim MS, Kim WJ, Oh WM, Lee EJ, Jung JY, Bae CS, Kim SH
- KMID: 2092887
- Korean J Anat.
- 2007 Mar;40(1):27-35.
Thioredoxin peroxidase (prdx)is an antioxidant defense enzyme and is involved in cell differentiation.We elucidated the localization and expression of prdx in the rat tooth germ,which undergoes dynamic morphological changes during... -
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